Major differences in gene expression in human coronary smooth muscle cells after nebivolol or metoprolol treatment

International Journal of Cardiology

Volumn 125, Issue 1, 2008, Pages 4-10

  Wolf, Sabine C ^a   Sauter, Gabriele ^a   Jobst, Jürgen ^a   Kempf, Volkard A ^a   Risler, Teut ^a   Brehm, Bernhard R ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Atherosclerosis; Beta blocker; Coronary smooth muscle cells; Metoprolol; Nebivolol

Indexed keywords

COLONY STIMULATING FACTOR 1; CYCLOOXYGENASE 2; GRANULOCYTE COLONY STIMULATING FACTOR; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; MESSENGER RNA; METOPROLOL; MONOCYTE CHEMOTACTIC PROTEIN 1; NEBIVOLOL; PLATELET DERIVED GROWTH FACTOR A; PROTEIN SELADIN 1; REGULATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 6; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; DOWN REGULATION; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; ONCOGENE; OXIDATIVE STRESS; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

EID: 39749203492     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.02.045     Document Type: Article

References (45)

1. J. Cockcroft Nebivolol: a review Expert Opin Pharmacother 5 2004 893 899
2. M.D. Flather M.C. Shibata A.J. Coats Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS) Eur Heart J 26 2005 215 225
3. B.R. Brehm S.C. Wolf D. Bertsch Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells Cardiovasc Res 49 2001 430 439
4. L.J. Ignarro M. Sisodia K. Trinh Nebivolol inhibits vascular smooth muscle cell proliferation by mechanisms involving nitric oxide but not cyclic GMP Nitric Oxide 7 2002 83 90
5. E. Schreiber P. Matthias M.M. Muller W. Schaffner Rapid detection of octamer binding proteins with ‘mini-extracts’, prepared from a small number of cells Nucleic Acids Res 17 1989 6419
6. R. Ross J.A. Glomset Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis Science 180 1973 1332 1339
7. V.J. Dzau R.C. Braun-Dullaeus D.G. Sedding Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies Nat Med 8 2002 1249 1256
8. S.M. Schwartz D. deBlois E.R. O'Brien The intima. Soil for atherosclerosis and restenosis Circ Res 77 1995 445 465
9. W.A. Boisvert Modulation of atherogenesis by chemokines Trends Cardiovasc Med 14 2004 161 165
10. H. Hagiwara M. Mitsumata T. Yamane X. Jin Y. Yoshida Laminar shear stress-induced GRO mRNA and protein expression in endothelial cells Circulation 98 1998 2584 2590
11. Y. Huo C. Weber S.B. Forlow The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium J Clin Invest 108 2001 1307 1314
12. U. Zeiffer A. Schober M. Lietz Neointimal smooth muscle cells display a proinflammatory phenotype resulting in increased leukocyte recruitment mediated by P-selectin and chemokines Circ Res 94 2004 776 784
13. P. Libby J.M. Ordovas L.K. Birinyi K.R. Auger C.A. Dinarello Inducible interleukin-1 gene expression in human vascular smooth muscle cells J Clin Invest 78 1986 1432 1438
14. S.K. Durum J.A. Schmidt J.J. Oppenheim Interleukin 1: an immunological perspective Annu Rev Immunol 3 1985 263 287
15. M.P. Bevilacqua J.S. Pober M.E. Wheeler R.S. Cotran M.A. Gimbrone Jr. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines J Clin Invest 76 1985 2003 2011
16. K. Isoda M. Shiigai N. Ishigami Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury Circulation 108 2003 516 518
17. M.A. Hernandez-Presa J.L. Martin-Ventura M. Ortego Atorvastatin reduces the expression of cyclooxygenase-2 in a rabbit model of atherosclerosis and in cultured vascular smooth muscle cells Atherosclerosis 160 2002 49 58
18. B. Beutler A. Cerami The biology of cachectin/TNF-a primary mediator of the host response Annu Rev Immunol 7 1989 625 655
19. T. Couffinhal C. Duplaa L. Labat Tumor necrosis factor-alpha stimulates ICAM-1 expression in human vascular smooth muscle cells Arterioscler Thromb 13 1993 407 414
20. R. Voisard M. Osswald R. Baur Expression of intercellular adhesion molecule-1 in human coronary endothelial and smooth muscle cells after stimulation with tumor necrosis factor-alpha Coron Artery Dis 9 1998 737 745
21. T.H. Lee G.W. Lee E.B. Ziff J. Vilcek Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts Mol Cell Biol 10 1990 1982 1988
22. L. Ye R. Mora N. Akhayani C.C. Haudenschild G. Liau Growth factor and cytokine-regulated hyaluronan-binding protein TSG-6 is localized to the injury-induced rat neointima and confers enhanced growth in vascular smooth muscle cells Circ Res 81 1997 289 296
23. P. Feng G. Liau Identification of a novel serum and growth factor-inducible gene in vascular smooth muscle cells J Biol Chem 268 1993 9387 9392
24. D. Di Stasi V. Vallacchi V. Campi DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis Int J Cancer 115 2005 224 230
25. C. Wu I. Miloslavskaya S. Demontis R. Maestro K. Galaktionov Regulation of cellular response to oncogenic and oxidative stress by Seladin-1 Nature 432 2004 640 645
26. I. Greeve I. Hermans-Borgmeyer C. Brellinger The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress J Neurosci 20 2000 7345 7352
27. R.J. Henning D.R. Sawmiller Vasoactive intestinal peptide: cardiovascular effects Cardiovasc Res 49 2001 27 37
28. D.R. Sawmiller R.J. Henning J. Cuevas W.I. Dehaven D.L. Vesely Coronary vascular effects of vasoactive intestinal peptide in the isolated perfused rat heart Neuropeptides 38 2004 289 297
29. L. Feliciano R.J. Henning Vagal nerve stimulation releases vasoactive intestinal peptide which significantly increases coronary artery blood flow Cardiovasc Res 40 1998 45 55
30. D.J. Lamb T.Y. Avades G.A. Ferns Endogenous neutralizing antibodies against platelet-derived growth factor-AA inhibit atherogenesis in the cholesterol-fed rabbit Arterioscler Thromb Vasc Biol 21 2001 997 1003
31. L. Boring J. Gosling M. Cleary I.F. Charo Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis Nature 394 1998 894 897
32. T.C. Dawson W.A. Kuziel T.A. Osahar N. Maeda Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice Atherosclerosis 143 1999 205 211
33. L. Gu Y. Okada S.K. Clinton Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice Mol Cell 2 1998 275 281
34. S.C. Wolf G. Sauter V. Kempf T. Risler B. Brehm Influence of nebivolol and metoprolol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in carotid arteries of rats treated with nebivolol Cell Physiol Biochem 19 2007 129 136
35. R. De Martin M. Hoeth R. Hofer-Warbinek J.A. Schmid The transcription factor NF-kappa B and the regulation of vascular cell function Arterioscler Thromb Vasc Biol 20 2000 E83 E88
36. F. Chen D.C. Kuhn S.C. Sun L.J. Gaydos L.M. Demers Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages Biochem Biophys Res Commun 214 1995 839 846
37. J.R. Matthews C.H. Botting M. Panico H.R. Morris R.T. Hay Inhibition of NF-kappaB DNA binding by nitric oxide Nucleic Acids Res 24 1996 2236 2242
38. N. Tzemos P.O. Lim T.M. MacDonald Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study Circulation 104 2001 511 514
39. H. Mollnau E. Schulz A. Daiber Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells Arterioscler Thromb Vasc Biol 23 2003 615 621
40. L. Cominacini P.A. Fratta U. Garbin Nebivolol and its 4-keto derivative increase nitric oxide in endothelial cells by reducing its oxidative inactivation J Am Coll Cardiol 42 2003 1838 1844
41. A.A. de Groot M.J. Mathy P.A. van Zwieten S.L. Peters Antioxidant activity of nebivolol in the rat aorta J Cardiovasc Pharmacol 43 2004 148 153
42. M. Oelze A. Daiber R. Brandes Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats Hypertension 48 2006 677 684
43. R.P. Mason L. Kalinowski R.F. Jacob A.M. Jacoby T. Malinski Nebivolol reduces nitroxidative stress and restores nitric oxide bioavailability in endothelium of black Americans Circulation 112 2005 3795 3801
44. A. Fratta Pasini U. Garbin M.C. Nava Nebivolol decreases oxidative stress in essential hypertensive patients and increases nitric oxide by reducing its oxidative inactivation J Hypertens 23 2005 589 596
45. S. Ghio G. Magrini A. Serio Effects of nebivolol in elderly heart failure patients with or without systolic left ventricular dysfunction: results of the SENIORS echocardiographic substudy Eur Heart J 27 2006 562 568