Volatile metabolic profiles of cell suspension cultures of Lavandula vera, Nicotiana tabacum and Helianthus annuus, cultivated under different regimes

Engineering in Life Sciences

Volumn 10, Issue 2, 2010, Pages 148-157

  Georgiev, Milen ^a   Georgiev, Vasil ^a   Penchev, Plamen ^b   Antonova, Daniela ^c   Pavlov, Atanas ^a   Ilieva, Mladenka ^a   Popov, Simeon ^c  

^a INSTITUTE OF MICROBIOLOGY   (Bulgaria)

^b UNIVERSITY OF PLOVDIV   (Bulgaria)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

Author keywords

Bioreactor; GC MS; Plant cell suspensions; Principal component analysis; Volatiles

Indexed keywords

AMBERLITE XAD-4 RESIN; ASTERACEAE; BIOLOGICAL ACTIVITIES; CELL SUSPENSION CULTURES; CULTURE MEDIUM; FIRST PRINCIPAL COMPONENTS; GC-MS; HELIANTHUS ANNUUS; LAMIACEAE; LAVANDULA VERA; METABOLIC PROFILES; NICOTIANA TABACUM; PLANT CELL SUSPENSION; PLANT CELL SUSPENSIONS; PRINCIPAL COMPONENTS; SECOND PHASE; SHAKE FLASKS; SOLANACEAE; STIRRED TANK REACTORS; TWO PHASE SYSTEMS;

BIOREACTORS; BOTTLES; CELL CULTURE; ESSENTIAL OILS; HYDROCARBONS; METABOLISM; PLANT CELL CULTURE; RESINS; SUSPENSIONS (FLUIDS);

PRINCIPAL COMPONENT ANALYSIS;

HYDROCARBON; POLACRILIN;

BIOREACTOR; CULTIVATION; DICOTYLEDON; HYDROCARBON; METABOLITE; PRINCIPAL COMPONENT ANALYSIS; RESIN; TOBACCO; VOLATILE SUBSTANCE;

ARTICLE; CELL SUSPENSION; CULTURE MEDIUM; HELIANTHUS ANNUUS; LAVENDER; MASS FRAGMENTOGRAPHY; METABOLITE; NONHUMAN; PLANT CELL; PLANT METABOLISM; SPECIES CULTIVATION; STIRRED REACTOR; SUNFLOWER; TOBACCO;

ASTERACEAE; HELIANTHUS ANNUUS; LAMIACEAE; LAVANDULA ANGUSTIFOLIA; NICOTIANA TABACUM; SOLANACEAE;

EID: 77950824585     PISSN: 16180240     EISSN: 16182863     Source Type: Journal    
DOI: 10.1002/elsc.200900090     Document Type: Article

References (26)

1. M. Georgiev, J. Weber, A. Maciuk, Bioprocessing of plant cell cultures for mass production of targeted compounds. Appl. Microbiol. Biotechnol. 2009, 83, 809-823.
2. R. Eibl, S. Werner, D. Eibl, Disposable bioreactors for plant liquid cultures at Litre-scale. Eng. Life Sci. 2009, 9, 156-164.
3. J. J. Zhong, Biochemical engineering of the production of plant-specific secondary metabolites by cell suspension cultures, in: T. Scheper, J. J. Zhong (Eds.), Advances in Biochemical Engineering/Biotechnology. Plant Cells, Springer, Berlin, Heidelberg 2001, 1-26.
4. A. Pavlov, S. Popov, E. Kovacheva, M. Georgiev, M. Ilieva, Volatile and polar compounds in Rosa damascena Mill 1803 cell suspension. J. Biotechnol. 2005, 118, 89-97.
5. J. Ludwig-Mueller, M. Georgiev, Th. Bley, Metabolite and hormonal status of hairy root cultures of Devil's claw (Harpagophytum procumbens) in flasks and in a bubble column bioreactor. Process Biochem. 2008, 43, 15-23.
6. U. Roessner, L. Willmitzer, A. R. Fernie, Metabolic profiling and biochemical phenotyping of plant systems. Plant Cell Rep. 2002, 21, 189-196.
7. N. Dudareva, F. Negre, D. A. Nagegowda, I. Orlova, Plant volatiles: recent advances and future prospects. Crit. Rev. Plant Sci. 2006, 25, 417-440.
8. Q-H. Zhang, G-T. Liu, F. Schlyter, G. Birgersson et al., Olfactory responses of lps duplicatus from Inner Mongolia, China to nonhost leaf and bark volatiles. J. Chem. Ecol. 2001, 27, 995-1009.
9. M. P. Ilieva, Production of biologically active substances by plant cell suspension cultures, DSc Thesis. Sofia, 2000, in Bulgarian.
10. E. M. Linsmayer, F. Skoog, Organic growth factor requirements of tobacco tissue cultures. Physiol. Plant. 1965, 181, 100-127.
11. H. Hendriks, H. J. Greets, Th. M. Malingere, The occurrence of valeranone and crypto-fauronol in the essential oil of Valeriana officinalis L.s.l. collected in the northern part of The Netherlands. Pharmaceutisch Weekblad Sci. Ed. 1981, 116, 1316-1320.
12. T. J. Smith, Squalene: potential chemopreventive agent. Exp. Opin. Investig. Drugs 2000, 9, 1841-1848.
13. E. Ryan, K. Galvin, T. P. O'Connor, A. R. Maguire, N. M. O'Brien, Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. Plant Food. Hum. Nutr. 2007, 62, 85-91.
14. L. M. Korulkina, G. E. Zhusupova, E. E. Shults, K. B. Erzhanov, Fatty-acid composition of two Limonium plant species. Chem. Nat. Compd. 2004, 40, 417-419.
15. Ch. Asche, M. Demeunynck, Antitumor carbazoles. Anti-Cancer Agents Med. Chem. 2007, 7, 247-267.
16. W. Nuttley, S. Harbinder, D. van der Kool, Regulation of distinct attractive and aversive mechanisms mediating benzaldehyde chemotaxis in Chenorhabisditis elegans. Learn. Mem. 2001, 8, 170-181.
17. J. Y. Deng, H. Y. Wei, Y. P. Huang, J. W. Du, Enhancement of attraction to sex pheromones of Spodoptera exigua by volatile compounds produced by host plants. J. Chem. Ecol. 2004, 30, 2037-2045.
18. G. Papanov, P. Bozov, P. Malakov, Triterpenoids from Lavandula spica. Phytochemistry 1992, 31, 1424-1426.
19. J. B. Harborne, C. A. Williams, Phytochemistry of the genus Lavandula, in: M. Lis-Balchin (Ed.), Lavender: the Genus Lavandula, Taylor and Francis, London and New York 2002, 86-99.
20. G. Hills, Industrial use of lipases to produce fatty acid esters. Eur. J. Lipid Sci. Technol. 2003, 105, 601-607.
21. M. K. Ratajczak, Y. T. Chris Ko, Y. Lange, T. L. Steck, K. Y. C. Lee, Cholesterol displacement from membrane phospholipids by hexadecanol. Biophys. J. 2007, 93, 2038-2047. (Pubitemid 47437586)
22. U. N. Das, Essential fatty acids - a review. Curr. Pharm. Biotechnol. 2006, 7, 467-482.
23. D. A. Vasselin, A. D. Westwell, C. S. Matthews, T. D. Bradshaw, M. F. G. Stevens, Structural studies on bioactive compounds. 40.1 synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzothiazoles. J. Med. Chem. 2006, 49, 3973-3981.
24. Y. H. Choi, H. Y. Kim, A. Hazekamp, C. Erkelens et al., Metabolomic differentiation of Cannabis sativa cultivars using 1H NMR spectroscopy and principal component analysis. J. Nat. Prod. 2004, 67, 953-957.
25. P. S. Belton, I. J. Colquhoun, E. K. Kemsley, I. Delgadillo, P. Roma, M. J. Dennis, M. Sharman, E. Holmes, J. K. Nicholson, M. Spraul, Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties. Food Chem. 1998, 61, 207-213.
26. A. Pavlov, M. Georgiev, I. Panchev, M. Ilieva, Optimization of rosmarinic acid production by Lavandula vera MM plant cell suspension in a laboratory bioreactor, Biotechnol. Prog. 2005, 21, 394-396.