Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation

Critical Care

Volumn 14, Issue 2, 2010, Pages

  Kim, Oh Y ^a   Monsel, Antoine ^b   Bertrand, Michèle ^b   Coriat, Pierre ^b   Cavaillon, Jean Marc ^a   Adib Conquy, Minou ^a  

^a INSTITUT PASTEUR   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; HLA DR11 ANTIGEN; HYDROCORTISONE; INTERLEUKIN 10; MEMBRANE ASSOCIATED RING CH 1 PROTEIN; UNCLASSIFIED DRUG; HLA DR ANTIGEN;

AGED; ANTIGEN EXPRESSION; ARTICLE; CAROTID ARTERY SURGERY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESCENDING AORTA SURGERY; DISEASE ASSOCIATION; DISEASE MARKER; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMMUNE RESPONSE; IN VITRO STUDY; MALE; MONOCYTE; PRIORITY JOURNAL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; UPREGULATION; ABDOMINAL AORTA; BIOSYNTHESIS; CAROTID ARTERY; CASE CONTROL STUDY; CYTOLOGY; GENE EXPRESSION; IMMUNOLOGY; METABOLISM; METHODOLOGY; MIDDLE AGED; POLYMERASE CHAIN REACTION;

AGED; ANTIGENS, CD14; AORTA, ABDOMINAL; CAROTID ARTERIES; CASE-CONTROL STUDIES; DOWN-REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HLA-DR ANTIGENS; HUMANS; MALE; MIDDLE AGED; MONOCYTES; POLYMERASE CHAIN REACTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 77950682477     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc8959     Document Type: Article

References (53)

1. Bone RC, Grodzin CJ, Balk RA. Sepsis: A new hypothesis for pathogenesis of the disease process. Chest 1997, 112:235-243. 10.1378/chest.112.1.235, 9228382.
2. Adib-Conquy M, Cavaillon JM. Compensatory anti-inflammatory response syndrome. Thromb Haemost 2009, 101:36-47.
3. Venet F, Chung CS, Kherouf H, Geeraert A, Malcus C, Poitevin F, Bohe J, Lepape A, Ayala A, Monneret G. Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients. Intensive Care Med 2009, 35:678-686. 10.1007/s00134-008-1337-8, 2789433, 18946659.
4. Muñoz C, Carlet J, Fitting C, Misset B, Bleriot JP, Cavaillon JM. Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest 1991, 88:1747-1754. 10.1172/JCI115493, 295719, 1939659.
5. McCall CE, Grosso-Wilmoth LM, LaRue K, Guzman RN, Cousart SL. Tolerance to endotoxin-induced expression of the interleukin-1β gene in blood neutrophils of humans with the sepsis syndrome. J Clin Invest 1993, 91:853-861. 10.1172/JCI116306, 288037, 7680670.
6. Maturana P, Puente J, Miranda D, Sepulveda C, Wolf ME, Mosnaim AD. Natural killer cell activity in patients with septic shock. J Crit Care 1991, 6:42-45.
7. Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 2006, 6:813-822. 10.1038/nri1943, 17039247.
8. Hershman MJ, Cheadle WG, Wellhausen SR, Davidon P, Polk HC. Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patients. Br J Surg 1990, 77:204-207. 10.1002/bjs.1800770225, 2317682.
9. Monneret G, Lepape A, Voirin N, Bohe J, Venet F, Debard AL, Thizy H, Bienvenu J, Gueyffier F, Vanhems P. Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock. Intensive Care Med 2006, 32:1175-1183. 10.1007/s00134-006-0204-8, 16741700.
10. Lekkou A, Karakantza M, Mouzaki A, Kalfarentzos F, Gogos CA. Cytokine production and monocyte HLA-DR expression as predictors of outcome for patients with community-acquired severe infections. Clin Diagn Lab Immunol 2004, 11:161-167. 321326, 14715564.
11. Richter A, Nebe T, Wendl K, Schuster K, Klaebisch G, Quintel M, Lorenz D, Post S, Trede M. HLA-DR expression in acute pancreatitis. Eur J Surg 1999, 165:947-951. 10.1080/110241599750008053, 10574102.
12. Haveman JW, Berg AP, Verhoeven EL, Nijsten MW, Dungen JJ, The HT, Zwaveling JH. HLA-DR expression on monocytes and systemic inflammation in patients with ruptured abdominal aortic aneurysms. Crit Care 2006, 10:R119. 10.1186/cc5017, 1751002, 16899122.
13. Franke A, Lante W, Zoeller LG, Kurig E, Weinhold C, Markewitz A. Delayed recovery of human leukocyte antigen-DR expression after cardiac surgery with early non-lethal postoperative complications: only an epiphenomenon?. Interact Cardiovasc Thorac Surg 2008, 7:207-211. 10.1510/icvts.2007.158899, 18055481.
14. Cheadle WG, Hershman MJ, Wellhausen SR, Polk HC. HLA-DR antigen expression on peripheral blood monocytes correlates with surgical infection. Am J Surg 1991, 161:639-645. 10.1016/0002-9610(91)91247-G, 1862821.
15. Berk JMM, Oldenburger RHJ, Berg AP, Klompmaker IJ, Mesander G, van Son WJ, Bij W, Slooff MJH, The TH. Low HLA DR expression on monocytes as a prognostic marker for bacterial sespsis after liver transplantation. Transplantation 1997, 63:1846-1848. 10.1097/00007890-199706270-00026, 9210517.
16. Muehlstedt SG, Lyte M, Rodriguez JL. Increased IL-10 production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia. Shock 2002, 17:443-450. 10.1097/00024382-200206000-00001, 12069178.
17. Satoh A, Miura T, Satoh K, Masamune A, Yamagiwa T, Sakai Y, Shibuya K, Takeda K, Kaku M, Shimosegawa T. Human leukocyte antigen-DR expression on peripheral monocytes as a predictive marker of sepsis during acute pancreatitis. Pancreas 2002, 25:245-250. 10.1097/00006676-200210000-00006, 12370535.
18. Venet F, Tissot S, Debard AL, Faudot C, Crampe C, Pachot A, Ayala A, Monneret G. Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: Correlation with severity and secondary septic shock. Crit Care Med 2007, 35:1910-1917. 10.1097/01.CCM.0000275271.77350.B6, 17568330.
19. Strohmeyer JC, Blume C, Meisel C, Doecke WD, Hummel M, Hoeflich C, Thiele K, Unbehaun A, Hetzer R, Volk HD. Standardized immune monitoring for the prediction of infections after cardiopulmonary bypass surgery in risk patients. Cytometry B Clin Cytom 2003, 53:54-62. 10.1002/cyto.b.10031, 12717692.
20. Fumeaux T, Pugin J. Is the measurement of monocytes HLA-DR expression useful in patients with sepsis?. Intensive Care Med 2006, 32:1106-1108. 10.1007/s00134-006-0205-7, 16741699.
21. Le Tulzo Y, Pangault C, Amiot L, Guilloux V, Tribut O, Arvieux C, Camus C, Fauchet R, Thomas R, Drenou B. Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock. Am J Respir Crit Care Med 2004, 169:1144-1151. 10.1164/rccm.200309-1329OC, 15028560.
22. Fumeaux T, Pugin J. Role of interleukin-10 in the intracellular sequestration of human leukocyte antigen-DR in monocytes during septic shock. Am J Respir Crit Care Med 2002, 166:1475-1482. 10.1164/rccm.200203-217OC, 12406851.
23. Thibodeau J, Bourgeois-Daigneault MC, Huppe G, Tremblay J, Aumont A, Houde M, Bartee E, Brunet A, Gauvreau ME, de Gassart A, Gatti E, Baril M, Cloutier M, Bontron S, Fruh K, Lamarre D, Steimle V. Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. Eur J Immunol 2008, 38:1225-1230. 10.1002/eji.200737902, 2759377, 18389477.
24. Matsuki Y, Ohmura-Hoshino M, Goto E, Aoki M, Mito-Yoshida M, Uematsu M, Hasegawa T, Koseki H, Ohara O, Nakayama M, Toyooka K, Matsuoka K, Hotta H, Yamamoto A, Ishido S. Novel regulation of MHC class II function in B cells. Embo J 2007, 26:846-854. 10.1038/sj.emboj.7601556, 1794403, 17255932.
25. De Gassart A, Camosseto V, Thibodeau J, Ceppi M, Catalan N, Pierre P, Gatti E. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. Proc Natl Acad Sci USA 2008, 105:3491-3496. 10.1073/pnas.0708874105, 2265198, 18305173.
26. Passlick B, Flieger D, Ziegler-Heitbrock HW. Identification and characterization of a novel monocyte subpopulation in human peripheral blood. Blood 1989, 74:2527-2534.
27. Ziegler-Heitbrock HW, Fingerle G, Strobel M, Schraut W, Stelter F, Schutt C, Passlick B, Pforte A. The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages. Eur J Immunol 1993, 23:2053-2058. 10.1002/eji.1830230902, 7690321.
28. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003, 19:71-82. 10.1016/S1074-7613(03)00174-2, 12871640.
29. Fingerle G, Pforte A, Passlick B, Blumenstein M, Strobel M, Ziegler-Heitbrock HWL. The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patients. Blood 1993, 82:3170-3176.
30. Skrzeczynska-Moncznik J, Bzowska M, Loseke S, Grage-Griebenow E, Zembala M, Pryjma J. Peripheral blood CD14high CD16+ monocytes are main producers of IL-10. Scand J Immunol 2008, 67:152-159. 10.1111/j.1365-3083.2007.02051.x, 18201370.
31. Petit-Bertron AF, Pédron T, Groß U, Coppée J-Y, Sansonetti PJ, Cavaillon J-M, Adib-Conquy M. Adherence modifies the regulation of gene expression induced by interleukin-10. Cytokine 2005, 29:1-12.
32. Adib-Conquy M, Adrie C, Fitting C, Gattoliat O, Beyaert R, Cavaillon JM. Up-regulation of MyD88s and SIGIRR, molecules inhibiting Toll-like receptor signaling, in monocytes from septic patients. Crit Care Med 2006, 34:2377-2385. 10.1097/01.CCM.0000233875.93866.88, 16850005.
33. Cabié A, Farkas J-C, Fitting C, Laurian C, Cormier J-M, Carlet J, Cavaillon J-M. High levels of portal TNFa during abdominal aortic surgery in man. Cytokine 1993, 5:448-453. 10.1016/1043-4666(93)90034-3, 8142599.
34. Kim OY, Monsel A, Bertrand M, Cavaillon JM, Coriat P, Adib-Conquy M. Translocation of bacterial NOD2 agonist and its link with inflammation. Crit Care 2009, 13:R124. 10.1186/cc7980, 2750177, 19638210.
35. Ziegler-Heitbrock H. Molecular mechanism in tolerance to lipopolysaccharide. J Inflamm. 1995, 45:13-26.
36. Volk T, Dopfmer UR, Schmutzler M, Rimpau S, Schnitzler H, Konertz W, Hoeflich C, Docke WD, Spies CD, Volk HD, Kox WJ. Stress induced IL-10 does not seem to be essential for early monocyte deactivation following cardiac surgery. Cytokine 2003, 24:237-243. 10.1016/S1043-4666(03)00090-5, 14609565.
37. Ates E, Yilmaz S, Erkasap S, Ihtiyar E, Kaya Y, Pehlivan T, Ustuner Z, Yasar B, Kiper H. Perioperative immunonutrition ameliorates the postoperative immune depression in patients with gastrointestinal system cancer (prospective clinical study in 42 patients). Acta Gastroenterol Belg 2004, 67:250-254.
38. Cavaillon JM, Munoz C, Fitting C, Misset B, Carlet J. Circulating cytokines: the tip of the iceberg?. Circ Shock 1992, 38:145-152.
39. Ziegler-Heitbrock L. The CD14+ CD16+ blood monocytes: their role in infection and inflammation. J Leukoc Biol 2007, 81:584-592. 10.1189/jlb.0806510, 17135573.
40. Belge KU, Dayyani F, Horelt A, Siedlar M, Frankenberger M, Frankenberger B, Espevik T, Ziegler-Heitbrock L. The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. J Immunol 2002, 168:3536-3542.
41. Frankenberger M, Pechumer H, Ziegler-Heitbrock HW. Interleukin-10 is upregulated in LPS tolerance. Journal of Inflammation 1995, 45:56-63.
42. Gessler P, Pretre R, Burki C, Rousson V, Frey B, Nadal D. Monocyte function-associated antigen expression during and after pediatric cardiac surgery. J Thorac Cardiovasc Surg 2005, 130:54-60. 10.1016/j.jtcvs.2005.01.008, 15999041.
43. Handy JM, Scott AJ, Cross AM, Sinha P, O'Dea KP, Takata M. HLA-DR expression and differential trafficking of monocyte subsets following low to intermediate risk surgery. Anaesthesia 2010, 65:27-35. 10.1111/j.1365-2044.2009.06161.x, 19889110.
44. Fumeaux T, Dufour J, Stern S, Pugin J. Immune monitoring of patients with septic shock by measurement of intraleukocyte cytokines. Intensive Care Medicine 2004, 30:2028-2037. 10.1007/s00134-004-2429-8, 15368036.
45. Asadullah K, Woiciechowsky C, Docke WD, Egerer K, Kox WJ, Vogel S, Sterry W, Volk HD. Very low monocytic HLA-DR expression indicates high risk of infection--immunomonitoring for patients after neurosurgery and patients during high dose steroid therapy. Eur J Emerg Med 1995, 2:184-190. 10.1097/00063110-199512000-00003, 9422205.
46. Volk T, Schmutzler M, Engelhardt L, Docke WD, Volk HD, Konertz W, Kox WJ. Influence of aminosteroid and glucocorticoid treatment on inflammation and immune function during cardiopulmonary bypass. Crit Care Med 2001, 29:2137-2142. 10.1097/00003246-200111000-00015, 11700410.
47. Elenkov IJ, Hasko G, Kovacs KJ, Vizi ES. Modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by selective alpha- and beta-adrenergic drugs in mice. J Neuroimmunol 1995, 61:123-131. 10.1016/0165-5728(95)00080-L, 7593548.
48. Zhu GF, Chancellor-Freeland C, Berman AS, Kage R, Leeman SE, Beller DI, Black PH. Endogenous substance P mediates cold water stress-induced increase in interleukin-6 secretion from peritoneal macrophages. J Neurosci 1996, 16:3745-3752.
49. Delgado M, Pozo D, Martinez C, Leceta J, Calvo JR, Ganea D, Gomariz RP. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit endotoxin-induced TNF-alpha production by macrophages: in vitro and in vivo studies. J Immunol 1999, 162:2358-2367.
50. Asehnoune K, Fitting C, Edouard AR, Minville V, Benhamou D, Cavaillon JM, Moine P. beta2-Adrenoceptor blockade partially restores ex vivo TNF production following hemorrhagic shock. Cytokine 2006, 34:212-218. 10.1016/j.cyto.2006.05.003, 16790355.
51. Tracey KJ. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 2007, 117:289-296. 10.1172/JCI30555, 1783813, 17273548.
52. Weijer S, Lauw FN, Branger J, Blink B, Poll T. Diminished interferon-g production and responsiveness after endotoxin administration to healhy humans. J Infect Dis 2002, 186:1748-1753. 10.1086/345675, 12447760.
53. Pachot A, Monneret G, Brion A, Venet F, Bohe J, Bienvenu J, Mougin B, Lepape A. Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients. Crit Care Med 2005, 33:31-38. 10.1097/01.CCM.0000150958.20209.A3, 15644645.