Standardized Immune Monitoring for the Prediction of Infections after Cardiopulmonary Bypass Surgery in Risk Patients

Cytometry Part B - Clinical Cytometry

Volumn 53, Issue 1, 2003, Pages 54-62

  Strohmeyer, Jens Christian ^a   Blume, Christian ^a   Meisel, Christian ^a   Doecke, Wolf Dietrich ^a   Hummel, Manfred ^b   Hoeflich, Conny ^a   Thiele, Kathi ^a   Unbehaun, Axel ^b   Hetzer, Roland ^b   Volk, Hans Dieter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DEUTSCHES HERZZENTRUM BERLIN   (Germany)

Author keywords

Cardiopulmonary bypass surgery; CD11b; CD84; Ex vivo elastase secretion; Ex vivo TNF secretion; HLA DR monocytes; IL 10; Immune monitoring; Prediction of infection

Indexed keywords

CD11B ANTIGEN; CD64 ANTIGEN; CD71 ANTIGEN; CD86 ANTIGEN; ELASTASE INHIBITOR; HLA DR ANTIGEN; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER;

ADULT; AREA UNDER THE CURVE; ARTICLE; AUTOANALYSIS; CARDIOPULMONARY BYPASS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; HIGH RISK PATIENT; HUMAN; IMMUNE STATUS; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MONOCYTE; POSTOPERATIVE INFECTION; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; RISK FACTOR; STANDARDIZATION; AGED; CORONARY ARTERY DISEASE; IMMUNOCOMPETENCE; IMMUNOLOGY; INFECTION; MIDDLE AGED; PATHOLOGY; POSTOPERATIVE COMPLICATION; PREDICTION AND FORECASTING;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARDIOPULMONARY BYPASS; CORONARY DISEASE; FEMALE; GRANULOCYTES; HUMANS; IMMUNOCOMPETENCE; INFECTION; MALE; MIDDLE AGED; MONOCYTES; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 10744232373     PISSN: 15524949     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.b.10031     Document Type: Article

References (37)

1. Butler J, Rocker GM, Westaby S. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 1993;55:552-559.
2. Kirklin JK, Westaby S, Blackstone EH, Kirklin JW, Chenoweth DE, Pacifico AD. Complement and the damaging effects of cardiopulmonary bypass. J Thorac Cardiovasc Surg 1983;86:845-857.
3. Sawa Y, Shimazaki Y, Kadoba K, Masai T, Fukuda H, Ohata T, Taniguchi K, Matsuda H. Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations. J Thorac Cardiovasc Surg 1996;111:29-35.
4. Kharazmi A, Andersen LW, Baek L, Valerius NH, Laub M, Rasmussen JP. Endotoxemia and enhanced generation of oxygen radicals by neutrophils from patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg 1989;98:381-385.
5. Landow L, Andersen LW. Splanchnic ischaemia and its role in multiple organ failure. Acta Anaesthesiol Scand 1994;38:626-639.
6. Hall RI, Smith MS, Rocker G. The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations. Anesth Analg 1997;85:766-782.
7. Butler J, Parker D, Pillai R, Westaby S, Shale DJ, Rocker GM. Effect of cardiopulmonary bypass on systemic release of neutrophil elastase and tumor necrosis factor. J Thorac Cardiovasc Surg 1993;105:25-30.
8. Hill GE. Cardiopulmonary bypass-induced inflammation: is it important? J Cardiothorac Vasc Anesth 1998;12(Suppl 1):21-25.
9. Bone RC. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med 1996;24:1125-1128.
10. McBride WT, Armstrong MA, Crockard AD, McMurray TJ, Rea JM. Cytokine balance and immunosuppressive changes at cardiac surgery: contrasting response between patients and isolated CPB circuits. Br J Anaesth 1995;75:724-733.
11. Rinder CS, Mathew JP, Rinder HM, Tracey JB, Davis E, Smith BR. Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender. J Lab Clin Med 1997;129:592-602.
12. Asadullah K, Woiciechowsky C, Docke WD, Liebenthal C, Wauer H, Kox W, Volk HD, Vogel S, Von Baehr R. Immunodepression following neurosurgical procedures. Crit Care Med 1995;23:1976-1983.
13. Woiciechowsky C, Schoning B, Lanksch WR, Volk HD, Docke WD. Mechanisms of brain-mediated systemic anti-inflammatory syndrome causing immunodepression. J Mol Med 1999;77:769-780.
14. Woiciechowsky C, Asadullah K, Nestler D, Eberhardt B, Platzer C, Schoning B, Glockner F, Lanksch WR, Volk HD, Docke WD. Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nat Med 1998;4:808-813.
15. Docke WD, Randow F, Syrbe U, Krausch D, Asadullah K, Reinke P, Volk HD, Kox W. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 1997;3:678-681.
16. van den Berk JM, Oldenburger RH, van den Berg AP, Klompmaker IJ, Mesander G, van Son WJ, van der Bij W, Sloof MJ, The TH. Low HLA-DR expression on monocytes as a prognostic marker for bacterial sepsis after liver transplantation. Transplantation 1997;63:1846-1848.
17. Wakefield CH, Carey PD, Foulds S, Monson JR, Guillou PJ. Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery. Br J Surg 1993;80:205-209.
18. Volk HD, Reinke P, Falck P, Staffa G, Briedigkeit H, v. Baehr R. Diagnostic value of an immune monitoring program for the clinical management of immunosuppressed patients with septic complications. Clin Transplantation 1989;3:246-252.
19. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864-874.
20. Rangel-Frausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel RP. The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 1995;273:117-123.
21. Oberhoffer M, Vogelsang H, Russwurm S, Hartung T, Reinhart K. Outcome prediction by traditional and new markers of inflammation in patients with sepsis. Clin Chem Lab Med 1999;37:363-368.
22. Reith HB, Mittelkotter U, Debus ES, Kussner C, Thiede A. Procalcitonin in early detection of postoperative complications. Dig Surg 1998;15:260-265.
23. Bochicchio GV, Napolitano LM, Joshi M, Knorr K, Tracy JK, Ilahi O, Scalea TM. Persistent systemic inflammatory response syndrome is predictive of nosocomial infection in trauma. J Trauma 2002;53:245-250.
24. Bossink AW, Groeneveld J, Hack CE, Thijs LG. Prediction of mortality in febrile medical patients: how useful are systemic inflammatory response syndrome and sepsis criteria? Chest 1998;113:1533-1541.
25. Gando S, Nanzaki S, Kemmotsu O. Disseminated intravascular coagulation and sustained systemic inflammatory response syndrome predict organ dysfunctions after trauma: application of clinical decision analysis. Ann Surg 1999;229:121-127.
26. Gessner JE, Heiken H, Tamm A, Schmidt RE. The IgG Fc receptor family. Ann Hematol 1998;76:231-248.
27. Davis BH, Bigelow NC, Curnutte JT, Ornvold K. Neutrophil CD64 expression: Potential diagnostic indicator of acute inflammation and therapeutic monitor of interferon-γ therapy. Lab Hem 1995;1:3-12.
28. Wakefield CH, Carey PD, Foulds S, Monson JR, Guillou PJ. Polymorphonuclear leukocyte activation: an early marker of the postsurgical sepsis response. Arch Surg 1993;128:390-395.
29. Takala A, Jousela I, Jansson SE, Olkkola KT, Takkunen O, Orpana A, Karonen SL, Repo H. Markers of systemic inflammation predicting organ failure in community-acquired septic shock. Clin Science 1999;97:529-538.
30. Spittler A, Razenberger M, Kupper H, Kaul M, Hackl W, Boltz-Nitulescu G, Fugger R, Roth E. Relationship between interleukin-6 plasma concentration in patients with sepsis, monocyte phenotype, monocyte phagocytic properties, and cytokine production. Clin Infect Dis 2000;31:1338-1342.
31. Manjuck J, Saha DC, Astiz M, Eales LJ, Rackow EC. Decreased response to recall antigens is associated with depressed costimulatory receptor expression in septic critically in patients. J Lab Clin Med 2000;135:153-160.
32. Randow F, Syrbe U, Meisel C, Krausch D, Zuckermann H, Platzer C, Volk HD. Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta. J Exp Med 1995;181:1887-1892.
33. Ertel W, Kremer JP, Kenney J, Steckholzer U, Jarrar D, Trentz O, Schildberg FW. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 1995;85:1341-1347.
34. Hensel M, Volk T, Docke WD, Kern F, Tschirna D, Egerer K, Konertz W, Kox WJ. Hyperprocalcitonemia in patients with noninfectious SIRS and pulmonary dysfunction associated with cardiopulmonary bypass. Anesthesiology 1998;89:93-104.
35. Smedly LA, Tonnesen MG, Sandhaus RA, Haslett C, Guthrie LA, Johnston Jr RB, Henson PM, Worthen GS. Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase. J Clin Invest 1986;77:1233-1243.
36. Ludemann J, Schulte KL, Hader O, Brehme S, Volk HD, Docke WD. Leukocyte/endothelium activation and interactions during femoral percutaneous transluminal angioplasty. Vasc Surg 2001;35:293-301.
37. Kawamura T, Wakusawa R, Inada K. Interleukin-10 and interleukin-1 receptor antagonists increase during cardiac surgery. Can J Anaesth 1997;44:38-42.