CITED2 mechanoregulation of matrix metalloproteinases

Annals of the New York Academy of Sciences

Volumn 1192, Issue , 2010, Pages 429-436

  Sun, Hui B ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

CITED2; Ets 1; Matrix metalloproteinases; Mechanical loading; Mechanoregulation; P300

Indexed keywords

CITED2 PROTEIN; MATRIX METALLOPROTEINASE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

CARTILAGE DEGENERATION; CONFERENCE PAPER; DOWN REGULATION; ENZYME REGULATION; HUMAN; MECHANOTRANSDUCTION; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; TRANSCRIPTION REGULATION;

EID: 77950658717     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05305.x     Document Type: Conference Paper

References (40)

1. Barr, A.E. et al. 2003. Repetitive, negligible force reaching in rats induces pathological overloading of upper extremity bones. J. Bone Miner. Res. 18: 2023-2032.
2. Burr, D.B., A.G. Robling & C.H. Turner. 2002. Effects of biomechanical stress on bones in animals. Bone 30: 781-786.
3. Honda, K. et al. 2000. The effects of high magnitude cyclic tensile load on cartilage matrixmetabolism in cultured chondrocytes. Eur. J. Cell Biol. 79: 601-609.
4. Jurvelin, J. et al. 1986. Softening of canine articular cartilage after immobilization of the knee joint. Clin. Orthop. Relat. Res. 207: 246-252.
5. Sun, H.B. &H. Yokota. 2001. AlteredmRNA level of matrix metalloproteinase-13 in MH7A synovial cells under mechanical loading and unloading. Bone 28: 399-403.
6. Kiviranta, I., et al. 1988.Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young beagle dogs. J. Orthop. Res. 6: 188-195.
7. Salter, R.B. 1989. The biologic concept of continuous passive motion of synovial joints. The first 18 years of basic research and its clinical application. Clin. Orthop. Relat. Res. 242: 12-25.
8. Blain, E.J. 2007. Mechanical regulation of matrix metalloproteinases. Front. Biosci. 12: 507-527.
9. Burrage, P.S., K.S.Mix&C.E. Brinckerhoff. 2006.Matrix metalloproteinases: role in arthritis. Front. Biosci. 11: 529-543.
10. Chakraborti, S. et al. 2003. Regulation of matrix metalloproteinases: an overview. Mol. Cell Biochem. 253: 269-285.
11. Pap, G. et al. 1998. Development of osteoarthritis in the knee joints of Wistar rats after strenuous running exercise in a running wheel by intracranial self-stimulation. Pathol. Res. Pract. 194: 41-47.
12. Kamekura, S. et al. 2005. Osteoarthritis development in novel experimentalmouse models induced by knee joint instability. Osteoarthritis Cartilage 13: 632-641.
13. Sun, H.B.&H.Yokota. 2001.Messenger-RNAexpression of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and transcription factors in rheumatic synovial cells under mechanical stimuli. Bone 28: 303-309.
14. Trindade, M.C. et al. 2004. Intermittent hydrostatic pressure inhibits matrix metalloproteinase and pro-inflammatory mediator release from human osteoarthritic chondrocytes in vitro. Osteoarthritis Cartilage 12: 729-735.
15. Sun, H.B. & H. Yokota. 2002. Reduction of cytokineinduced expression and activity of MMP-1 and MMP- 13 by mechanical strain in MH7A rheumatoid synovial cells. Matrix Biol. 21: 263-270.
16. Agarwal, S. et al. 2003. A central role for the nuclear factor-kappaB pathway in anti-inflammatory and proinflammatory actions of mechanical strain. FASEB J. 17: 899-901.
17. Bhattacharya, S. et al. 1999. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev. 13: 64-75.
18. Sun, H.B. et al. 1998. MRG1, the product of a melanocyte-specific gene related gene, is a cytokineinducible transcription factor with transformation activity. Proc. Natl. Acad. Sci. USA 95: 13555-13560.
19. Yokota, H., M.B. Goldring & H.B. Sun. 2003. CITED2- mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear. J. Biol. Chem. 278: 47275-47280.
20. Barbera, J.P. et al. 2002. Folic acid prevents exencephaly in Cited2 deficient mice. Hum.Mol. Genet. 11: 283-293.
21. Kranc, K.R. et al. 2003. Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF. Mol. Cell Biol. 23: 7658-7666.
22. Bamforth, S.D. et al. 2001. Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat. Genet. 29: 469-474.
23. Bai, L. & J.L. Merchant. 2007. A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. FEBS Lett. 581: 5904-5910.
24. Freedman, S.J. et al. 2003. Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2. Nat. Struct. Biol. 10: 504-512.
25. Braganca, J. et al. 2003. Physical and functional interactions among AP-2 transcription factors, p300/CREBbinding protein, and CITED2. J. Biol. Chem. 278: 16021-16029.
26. Dial, R., Z.Y. Sun & S.J. Freedman. 2003. Three conformational states of the p300 CH1 domain define its functional properties. Biochemistry 42: 9937-9945.
27. Horvai, A.E. et al. 1997.Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc. Natl. Acad. Sci. USA 94: 1074-1079.
28. Chou, Y.T. & Y.C. Yang. 2006. Post-transcriptional control of Cited2 by transforming growth factor beta. Regulation via Smads and Cited2 coding region. J. Biol. Chem. 281: 18451-18462.
29. Leung, M.K. et al. 1999.Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1. Genomics 61: 307-313.
30. Lin, M.C. et al. 1997. Shear stress induction of the tissue factor gene. J. Clin. Invest. 99: 737-744.
31. Han, B. et al. 2001. MRG1 expression in fibroblasts is regulated by Sp1/Sp3 and an Ets transcription factor. J. Biol. Chem. 276: 7937-7942.
32. Dittmer, J. 2003. The biology of theEts1 proto-oncogene. Mol. Cancer 2: 29.
33. Goldring,M.B. et al. 1994. Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes. J. Clin. Invest. 94: 2307-2316.
34. Lee, J.Y. et al. 2009. Identification of CITED2 as a negative regulator of fracture healing. Biochem. Biophys. Res. Commun. 387: 641-645.
35. Nye, J.A. et al. 1992. Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif. Genes. Dev. 6: 975-990.
36. Millward-Sadler, S.J. et al. 2000. Mechanotransduction via integrins and interleukin-4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes. Arthritis Rheum. 43: 2091-2099.
37. Ferretti,M. et al. 2005.Anti-inflammatory effects of continuous passive motion on meniscal fibrocartilage. J. Orthop. Res. 23: 1165-1171.
38. Tanaka, S.M. et al. 2005. Osteoblast responses one hour after load-induced fluid flow in a three-dimensional porous matrix. Calcif. Tissue Int. 76: 261-271.
39. Sun, H.B. et al. 2008. Coordinate regulation of IL-1beta andMMP-13 in rat tendons following subrupture fatigue damage. Clin. Orthop. Relat. Res.. 466: 1555-1561.
40. Asanuma, K. et al. 2003. Uniaxial strain upregulates matrix-degrading enzymes produced by human vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 284: H1778-H1784.