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Volumn 12, Issue 2, 2010, Pages

Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; STROMELYSIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; IMATINIB; MATRIX METALLOPROTEINASE; MESSENGER RNA; PIPERAZINE DERIVATIVE; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

EID: 77950652973     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2981     Document Type: Article
Times cited : (76)

References (45)
  • 1
    • 0024353803 scopus 로고
    • Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. Studies on secretion by synovial fibroblast-like cells and immunohistologic localization
    • Lafyatis R, Thompson NL, Remmers EF, Flanders KC, Roche NS, Kim SJ, Case JP, Sporn MB, Roberts AB, Wilder RL. Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. Studies on secretion by synovial fibroblast-like cells and immunohistologic localization. J Immunol 1989, 143:1142-1148.
    • (1989) J Immunol , vol.143 , pp. 1142-1148
    • Lafyatis, R.1    Thompson, N.L.2    Remmers, E.F.3    Flanders, K.C.4    Roche, N.S.5    Kim, S.J.6    Case, J.P.7    Sporn, M.B.8    Roberts, A.B.9    Wilder, R.L.10
  • 2
    • 0026099688 scopus 로고
    • Production of platelet derived growth factor B chain (PDGF-B/c-sis) mrna and immunoreactive PDGF B-like polypeptide by rheumatoid synovium: coexpression with heparin binding acidic fibroblast growth factor-1
    • Remmers EF, Sano H, Lafyatis R, Case JP, Kumkumian GK, Hla T, Maciag T, Wilder RL. Production of platelet derived growth factor B chain (PDGF-B/c-sis) mrna and immunoreactive PDGF B-like polypeptide by rheumatoid synovium: coexpression with heparin binding acidic fibroblast growth factor-1. J Rheumatol 1991, 18:7-13.
    • (1991) J Rheumatol , vol.18 , pp. 7-13
    • Remmers, E.F.1    Sano, H.2    Lafyatis, R.3    Case, J.P.4    Kumkumian, G.K.5    Hla, T.6    Maciag, T.7    Wilder, R.L.8
  • 3
    • 0025936026 scopus 로고
    • Identification of the major fibroblast growth factors released spontaneously in inflammatory arthritis as platelet derived growth factor and tumour necrosis factor-alpha
    • 1554160, 1914237
    • Thornton SC, Por SB, Penny R, Richter M, Shelley L, Breit SN. Identification of the major fibroblast growth factors released spontaneously in inflammatory arthritis as platelet derived growth factor and tumour necrosis factor-alpha. Clin Exp Immunol 1991, 86:79-86. 1554160, 1914237.
    • (1991) Clin Exp Immunol , vol.86 , pp. 79-86
    • Thornton, S.C.1    Por, S.B.2    Penny, R.3    Richter, M.4    Shelley, L.5    Breit, S.N.6
  • 4
    • 0025838313 scopus 로고
    • Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction
    • 1554206, 1747946
    • Chu CQ, Field M, Abney E, Zheng RQ, Allard S, Feldmann M, Maini RN. Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol 1991, 86:380-386. 1554206, 1747946.
    • (1991) Clin Exp Immunol , vol.86 , pp. 380-386
    • Chu, C.Q.1    Field, M.2    Abney, E.3    Zheng, R.Q.4    Allard, S.5    Feldmann, M.6    Maini, R.N.7
  • 5
    • 0026341684 scopus 로고
    • Platelet-derived growth factors and heparin-binding (fibroblast) growth factors in the synovial tissue pathology of rheumatoid arthritis
    • Remmers EF, Sano H, Wilder RL. Platelet-derived growth factors and heparin-binding (fibroblast) growth factors in the synovial tissue pathology of rheumatoid arthritis. Semin Arthritis Rheum 1991, 21:191-199.
    • (1991) Semin Arthritis Rheum , vol.21 , pp. 191-199
    • Remmers, E.F.1    Sano, H.2    Wilder, R.L.3
  • 7
    • 0025130557 scopus 로고
    • Antagonistic and agonistic effects of transforming growth factor-beta and IL-1 in rheumatoid synovium
    • Wahl SM, Allen JB, Wong HL, Dougherty SF, Ellingsworth LR. Antagonistic and agonistic effects of transforming growth factor-beta and IL-1 in rheumatoid synovium. J Immunol 1990, 145:2514-2519.
    • (1990) J Immunol , vol.145 , pp. 2514-2519
    • Wahl, S.M.1    Allen, J.B.2    Wong, H.L.3    Dougherty, S.F.4    Ellingsworth, L.R.5
  • 9
    • 0026656850 scopus 로고
    • Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice
    • 49712, 1502148
    • Thorbecke GJ, Shah R, Leu CH, Kuruvilla AP, Hardison AM, Palladino MA. Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice. Proc Natl Acad Sci USA 1992, 89:7375-7379. 49712, 1502148.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4    Hardison, A.M.5    Palladino, M.A.6
  • 10
    • 0025017687 scopus 로고
    • Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta
    • 2187661, 2295877
    • Allen JB, Manthey CL, Hand AR, Ohura K, Ellingsworth L, Wahl SM. Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med 1990, 171:231-247. 2187661, 2295877.
    • (1990) J Exp Med , vol.171 , pp. 231-247
    • Allen, J.B.1    Manthey, C.L.2    Hand, A.R.3    Ohura, K.4    Ellingsworth, L.5    Wahl, S.M.6
  • 11
    • 0024357303 scopus 로고
    • Platelet-derived growth factor and IL-1 interactions in rheumatoid arthritis. Regulation of synoviocyte proliferation, prostaglandin production, and collagenase transcription
    • Kumkumian GK, Lafyatis R, Remmers EF, Case JP, Kim SJ, Wilder RL. Platelet-derived growth factor and IL-1 interactions in rheumatoid arthritis. Regulation of synoviocyte proliferation, prostaglandin production, and collagenase transcription. J Immunol 1989, 143:833-837.
    • (1989) J Immunol , vol.143 , pp. 833-837
    • Kumkumian, G.K.1    Lafyatis, R.2    Remmers, E.F.3    Case, J.P.4    Kim, S.J.5    Wilder, R.L.6
  • 12
    • 8444237393 scopus 로고    scopus 로고
    • Platelet-derived growth factor-AA increases IL-1beta and IL-8 expression and activates NF-kappab in rheumatoid fibroblast-like synoviocytes
    • Cheon H, Sun YK, Yu SJ, Lee YH, Ji JD, Song GG, Lee JH, Kim MK, Sohn J. Platelet-derived growth factor-AA increases IL-1beta and IL-8 expression and activates NF-kappab in rheumatoid fibroblast-like synoviocytes. Scand J Immunol 2004, 60:455-462.
    • (2004) Scand J Immunol , vol.60 , pp. 455-462
    • Cheon, H.1    Sun, Y.K.2    Yu, S.J.3    Lee, Y.H.4    Ji, J.D.5    Song, G.G.6    Lee, J.H.7    Kim, M.K.8    Sohn, J.9
  • 13
    • 33744792284 scopus 로고    scopus 로고
    • Transforming growth factor beta 1(TGF-beta1) down-regulates tnfalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappab-mediated transcriptional repression
    • Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY. Transforming growth factor beta 1(TGF-beta1) down-regulates tnfalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappab-mediated transcriptional repression. Immunol Lett 2006, 105:159-166.
    • (2006) Immunol Lett , vol.105 , pp. 159-166
    • Cho, M.L.1    Min, S.Y.2    Chang, S.H.3    Kim, K.W.4    Heo, S.B.5    Lee, S.H.6    Park, S.H.7    Cho, C.S.8    Kim, H.Y.9
  • 14
    • 38449112810 scopus 로고    scopus 로고
    • Acquisition, culture, and phenotyping of synovial fibroblasts
    • Rosengren S, Boyle DL, Firestein GS. Acquisition, culture, and phenotyping of synovial fibroblasts. Methods Mol Med 2007, 135:365-375.
    • (2007) Methods Mol Med , vol.135 , pp. 365-375
    • Rosengren, S.1    Boyle, D.L.2    Firestein, G.S.3
  • 16
    • 54349089048 scopus 로고    scopus 로고
    • Utility of animal models for identification of potential therapeutics for rheumatoid arthritis
    • Hegen M, Keith JC, Collins M, Nickerson-Nutter CL. Utility of animal models for identification of potential therapeutics for rheumatoid arthritis. Ann Rheum Dis 2008, 67:1505-1515.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1505-1515
    • Hegen, M.1    Keith, J.C.2    Collins, M.3    Nickerson-Nutter, C.L.4
  • 17
    • 0028290831 scopus 로고
    • Cytokine interactions promoting DNA synthesis in human synovial fibroblasts
    • Hamilton JA, Butler DM, Stanton H. Cytokine interactions promoting DNA synthesis in human synovial fibroblasts. J Rheumatol 1994, 21:797-803.
    • (1994) J Rheumatol , vol.21 , pp. 797-803
    • Hamilton, J.A.1    Butler, D.M.2    Stanton, H.3
  • 19
    • 0033816156 scopus 로고    scopus 로고
    • Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
    • Buchdunger E, Cioffi CL, Law N, Stover D, Ohno-Jones S, Druker BJ, Lydon NB. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther 2000, 295:139-145.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 139-145
    • Buchdunger, E.1    Cioffi, C.L.2    Law, N.3    Stover, D.4    Ohno-Jones, S.5    Druker, B.J.6    Lydon, N.B.7
  • 21
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • Carroll M, Ohno-Jones S, Tamura S, Buchdunger E, Zimmermann J, Lydon NB, Gilliland DG, Druker BJ. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 1997, 90:4947-4952.
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3    Buchdunger, E.4    Zimmermann, J.5    Lydon, N.B.6    Gilliland, D.G.7    Druker, B.J.8
  • 22
    • 33645875870 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits proliferation of rheumatoid synovial fibroblast-like cells and phosphorylation of Gab adapter proteins activated by platelet-derived growth factor
    • 1809657, 16634808
    • Kameda H, Ishigami H, Suzuki M, Abe T, Takeuchi T. Imatinib mesylate inhibits proliferation of rheumatoid synovial fibroblast-like cells and phosphorylation of Gab adapter proteins activated by platelet-derived growth factor. Clin Exp Immunol 2006, 144:335-341. 1809657, 16634808.
    • (2006) Clin Exp Immunol , vol.144 , pp. 335-341
    • Kameda, H.1    Ishigami, H.2    Suzuki, M.3    Abe, T.4    Takeuchi, T.5
  • 26
    • 15244339164 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis
    • 524221, 15520863
    • Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J Clin Invest 2004, 114:1308-1316. 524221, 15520863.
    • (2004) J Clin Invest , vol.114 , pp. 1308-1316
    • Daniels, C.E.1    Wilkes, M.C.2    Edens, M.3    Kottom, T.J.4    Murphy, S.J.5    Limper, A.H.6    Leof, E.B.7
  • 27
    • 11244292291 scopus 로고    scopus 로고
    • Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
    • Wang S, Wilkes MC, Leof EB, Hirschberg R. Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. Faseb J 2005, 19:1-11.
    • (2005) Faseb J , vol.19 , pp. 1-11
    • Wang, S.1    Wilkes, M.C.2    Leof, E.B.3    Hirschberg, R.4
  • 28
    • 0026742317 scopus 로고
    • Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells
    • 364590, 1321334
    • Kavanaugh WM, Klippel A, Escobedo JA, Williams LT. Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells. Mol Cell Biol 1992, 12:3415-3424. 364590, 1321334.
    • (1992) Mol Cell Biol , vol.12 , pp. 3415-3424
    • Kavanaugh, W.M.1    Klippel, A.2    Escobedo, J.A.3    Williams, L.T.4
  • 29
    • 0036271952 scopus 로고    scopus 로고
    • Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts
    • Kim G, Jun JB, Elkon KB. Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 2002, 46:1504-1511.
    • (2002) Arthritis Rheum , vol.46 , pp. 1504-1511
    • Kim, G.1    Jun, J.B.2    Elkon, K.B.3
  • 30
    • 0029893734 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression
    • Mucsi I, Skorecki KL, Goldberg HJ. Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression. J Biol Chem 1996, 271:16567-16572.
    • (1996) J Biol Chem , vol.271 , pp. 16567-16572
    • Mucsi, I.1    Skorecki, K.L.2    Goldberg, H.J.3
  • 31
    • 0032547385 scopus 로고    scopus 로고
    • Signal transduction via platelet-derived growth factor receptors
    • Heldin CH, Ostman A, Ronnstrand L. Signal transduction via platelet-derived growth factor receptors. Biochim Biophys Acta 1998, 1378:F79-113.
    • (1998) Biochim Biophys Acta , vol.1378
    • Heldin, C.H.1    Ostman, A.2    Ronnstrand, L.3
  • 32
    • 34447324890 scopus 로고    scopus 로고
    • Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappab and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes
    • Xu H, He Y, Yang X, Liang L, Zhan Z, Ye Y, Yang X, Lian F, Sun L. Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappab and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. Rheumatology (Oxford) 2007, 46:920-926.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 920-926
    • Xu, H.1    He, Y.2    Yang, X.3    Liang, L.4    Zhan, Z.5    Ye, Y.6    Yang, X.7    Lian, F.8    Sun, L.9
  • 33
    • 5644289875 scopus 로고    scopus 로고
    • IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappab- and PI3-kinase/Akt-dependent pathways
    • 400429, 15059275
    • Hwang SY, Kim JY, Kim KW, Park MK, Moon Y, Kim WU, Kim HY. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappab- and PI3-kinase/Akt-dependent pathways. Arthritis Res Ther 2004, 6:R120-128. 400429, 15059275.
    • (2004) Arthritis Res Ther , vol.6
    • Hwang, S.Y.1    Kim, J.Y.2    Kim, K.W.3    Park, M.K.4    Moon, Y.5    Kim, W.U.6    Kim, H.Y.7
  • 37
    • 33750470841 scopus 로고    scopus 로고
    • Imatinib combined chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: major challenges in current practice
    • Yanada M, Naoe T. Imatinib combined chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: major challenges in current practice. Leuk Lymphoma 2006, 47:1747-1753.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1747-1753
    • Yanada, M.1    Naoe, T.2
  • 38
    • 60549100690 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumor: a clinical overview
    • viii
    • Quek R, George S. Gastrointestinal stromal tumor: a clinical overview. Hematol Oncol Clin North Am 2009, 23:69-78. viii.
    • (2009) Hematol Oncol Clin North Am , vol.23 , pp. 69-78
    • Quek, R.1    George, S.2
  • 39
    • 0042388478 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with imatinib mesylate: clinical improvement in three refractory cases
    • Eklund KK, Joensuu H. Treatment of rheumatoid arthritis with imatinib mesylate: clinical improvement in three refractory cases. Ann Med 2003, 35:362-367.
    • (2003) Ann Med , vol.35 , pp. 362-367
    • Eklund, K.K.1    Joensuu, H.2
  • 40
    • 0345328726 scopus 로고    scopus 로고
    • Efficacy of imatinib mesylate (STI571) treatment for a patient with rheumatoid arthritis developing chronic myelogenous leukemia
    • Miyachi K, Ihara A, Hankins RW, Murai R, Maehiro S, Miyashita H. Efficacy of imatinib mesylate (STI571) treatment for a patient with rheumatoid arthritis developing chronic myelogenous leukemia. Clin Rheumatol 2003, 22:329-332.
    • (2003) Clin Rheumatol , vol.22 , pp. 329-332
    • Miyachi, K.1    Ihara, A.2    Hankins, R.W.3    Murai, R.4    Maehiro, S.5    Miyashita, H.6
  • 43
    • 34447639395 scopus 로고    scopus 로고
    • Modulation of T-effector function by imatinib at the level of cytokine secretion
    • Leder C, Ortler S, Seggewiss R, Einsele H, Wiendl H. Modulation of T-effector function by imatinib at the level of cytokine secretion. Exp Hematol 2007, 35:1266-1271.
    • (2007) Exp Hematol , vol.35 , pp. 1266-1271
    • Leder, C.1    Ortler, S.2    Seggewiss, R.3    Einsele, H.4    Wiendl, H.5
  • 44
    • 30044449181 scopus 로고    scopus 로고
    • FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance
    • Taylor JR, Brownlow N, Domin J, Dibb NJ. FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance. Oncogene 2006, 25:147-151.
    • (2006) Oncogene , vol.25 , pp. 147-151
    • Taylor, J.R.1    Brownlow, N.2    Domin, J.3    Dibb, N.J.4
  • 45
    • 23444462473 scopus 로고    scopus 로고
    • Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis
    • 1755598, 16014680
    • Juurikivi A, Sandler C, Lindstedt KA, Kovanen PT, Juutilainen T, Leskinen MJ, Maki T, Eklund KK. Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis. Ann Rheum Dis 2005, 64:1126-1131. 1755598, 16014680.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1126-1131
    • Juurikivi, A.1    Sandler, C.2    Lindstedt, K.A.3    Kovanen, P.T.4    Juutilainen, T.5    Leskinen, M.J.6    Maki, T.7    Eklund, K.K.8


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