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Volumn 11, Issue 6, 2010, Pages 796-801

Suppression of water as a nucleophile in Candida antarctica lipase B catalysis

(7) Larsen, Marianne Wittrup a,b Zielinska, Dorota F a Martinelle, Mats a Hidalgo, Aurelio c Jensen, Lars Juhl d Bornscheuer, Uwe T b Hult, Karl a

a ALBANOVA UNIVERSITY CENTER (Sweden)

b UNIVERSITY OF GREIFSWALD (Germany)

c CSIC (Spain)

d University of Copenhagen (Denmark)

Author keywords

Candida antarctica lipase b; Hydrolysis; Library screening; Mutagenesis; Rational design transacylation

Indexed keywords

BUTANOL; BUTYRIC ACID DERIVATIVE; LIPASE B; NUCLEOPHILE; VINYL DERIVATIVE; WATER;

ACYLATION; ARTICLE; CANDIDA ANTARCTICA; CATALYSIS; CONTROLLED STUDY; HYDROLYSIS; HYDROPHILICITY; MUTANT; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

AMINO ACID SUBSTITUTION; BINDING SITES; BIOCATALYSIS; CANDIDA; CATALYTIC DOMAIN; COMPUTER SIMULATION; HYDROLYSIS; LIPASE; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; WATER;

CANDIDA ANTARCTICA;

EID: 77950635205 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.200900743 Document Type: Article

Times cited : (38)

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