Nonresponse to clozapine and premorbid functioning in treatment refractory schizophrenia

Comprehensive Psychiatry

Volumn 51, Issue 3, 2010, Pages 298-302

  Kelly, Deanna L ^a   Feldman, Stephanie ^a   Boggs, Douglas L ^a   Gale, Elizabeth ^a   Conley, Robert R ^a  

^a MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE;

ADULT; ARTICLE; BRIEF PSYCHIATRIC RATING SCALE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DOSE TITRATION; EDUCATIONAL STATUS; FEMALE; HOSTILITY; HUMAN; MALE; MARRIAGE; MORBIDITY; RACE; SCHIZOPHRENIA; TREATMENT DURATION; TREATMENT RESPONSE;

ADAPTATION, PSYCHOLOGICAL; ADULT; ANTIPSYCHOTIC AGENTS; BRIEF PSYCHIATRIC RATING SCALE; CLOZAPINE; FEMALE; HUMANS; MALE; MIDDLE AGED; PSYCHOMETRICS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SOCIAL ADJUSTMENT; TREATMENT FAILURE;

EID: 77950626994     PISSN: 0010440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.comppsych.2009.07.003     Document Type: Article

References (27)

1. Schmael C., Georgi A., Krumm B., Buerger C., Deschner M., Nothen M.M., et al. Premorbid adjustment in schizophrenia-an important aspect of phenotype definition. Schizophr Res 92 (2007) 50-62
2. Picchioni M.M., Toulopoulou T., Landau S., Davies N., Ribchester T., and Murray R.M. Neurological abnormalities in schizophrenic twins. Biol Psychiatry 59 4 (2006) 341-348
3. Walshe M., McDonald C., Grech A., Schulze K., Bramon E., and Murray R.M. Premorbid functioning in the unaffected siblings of patients with familial and nonfamilial schizophrenia. Schizophr Res 81 suppl 1 (2006) 272
4. Gornick M.C., Addington A.M., Sporn A., Gogtay N., Greenstein D., Lenane M., et al. Dysbindin (DTNBP1, 6p22.3) is associated with childhood onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS). J Austism Dev Disord 35 (2005) 831-838
5. Addington J., and Addington D. Premorbid functioning, cognitive functioning, symptoms and outcome in schizophrenia. J Psychiatry Neurosci 18 1 (1993) 18-23
6. Strous R.D., Alvir J.M., Robinson D., gal G., Sheitman B., Chakos M., et al. Premorbid functioning in schizophrenia: relation to baseline symptoms, treatment response, and medication side effects. Schizophr Bull 30 2 (2004) 265-278
7. Milev P., Ho B.C., Arndt S., and Andreasen N.C. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am J Psychiatry 162 3 (2005) 495-506
8. Amminger G.P., Resch F., Mutschlechner R., Friedrich M.H., and Ernst E. Premorbid adjustment and remission of positive symptoms in first-episode psychosis. Eur Child Adolesc Psychiatry 6 (1997) 212-218
9. Rabinowitz J., Harvey P.D., Eerdekens M., and Davidson M. Premorbid functioning and treatment in recent-onset schizophrenia. Br J Psychiatry 189 (2006) 31-35
10. Crespo-Facorro B., Pelayo-Teran J.M., Perez-Iglesias R., Ramirez-Bonilla M., Martinez-Garcia O., Pardo-Garcia G., et al. Predictors of acute treatment response in patients with a first episode of non-affective psychosis: sociodemographics, premorbid and clinical variables. J Psychiatr Res 41 (2007) 659-666
11. Tabatabaee M., Sharifi V., Alaghband-rad J., Amini H., Boroumand M., Omid A., et al. Acute treatment response and its predictors in patients with first-episode psychosis in Iran. Australas Psychiatry 16 (2008) 125-129
12. Lieberman J.A., Koreen A.R., Chakos M., Sheitman B., Woerner M., Alvir J.M., et al. Factors influencing treatment response and outcome in first-episode schizophrenia: implications for understanding the pathophysiology of schizophrenia. J Clin Psychiatry 57 suppl 9 (1996) 5-9
13. Conley R.C., and Kelly D.L. Management of treatment-resistant schizophrenia. Biol Psychiatry 50 (2001) 898-911
14. Friedman L., Knutson L., Shurell M., and Meltzer H.Y. Prefrontal sulcal prominence is inversely related to response to clozapine in schizophrenia. Biol Psychiatry 29 9 (1991) 865-877
15. Caspi A., Reichenberg A., Weiser M., Rabinowitz J., Shmushkevich M., Lubin G., et al. Premorbid behavioral and intellectual functioning in schizophrenia patients with poor response to treatment with antipsychotic drugs. Schizophr Res 94 (2007) 45-49
16. Cannon-Spoor H.E., Potkin S.G., and Wyatt R.J. Measurement of premorbid adjustment in chronic schizophrenia. Schizophr Bull 8 3 (1982) 470-484
17. Kirkpatrick B., Buchanan R.W., McKenney P.D., Alphs L.D., and Carpenter Jr. W.T. The Schedule for the Deficit Syndrome: an instrument for research in schizophrenia. Psychiatry Res 30 (1989) 119-123
18. Hawk A.B., Carpenter Jr. W.T., and Strauss J.S. Diagnostic criteria and five-year outcome in schizophrenia. A report from the International Pilot Study of schizophrenia. Arch Gen Psychiatry 32 (1975) 343-347
19. Fuller R., Nopoulos P., Arndt S., O'Leary D., Ho B.C., and Andreasen N.C. Longitudinal assessment of premorbid cognitive functioning in patients with schizophrenia through examination of standardized scholastic test performance. Am J Psychiatry 159 7 (2002) 1183-1189
20. Reichenberg A., Weiser M., Rapp M.A., Rabinowitz J., Caspi A., Schmeidler J., et al. Elaboration on premorbid intellectual performance in schizophrenia: premorbid intellectual decline and risk for schizophrenia. Arch Gen Psychiatry 62 12 (2005) 1297-1304
21. Masi G., Mucci M., and Pari C. Children with schizophrenia: clinical picture and pharmacological treatment. CNS Drugs 20 (2006) 841-866
22. Rosenheck R., Lawson W., Crayton J., Cramer J., Xu W., Thomas J., et al., for the Dept. of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Predictors of differential response to clozapine and haloperidol. Biol Psychiatry 44 (1998) 475-482
23. Meltzer H.Y., Bastani B., Kwon K.Y., Ramirez L.F., Burnett S., and Sharpe J. A prospective study of clozapine in treatment-resistant schizophrenic patients. I. Preliminary report. Psychopharmacology (Berl) 99 Suppl (1989) S68-S72
24. Stern R.G., Kahn R.S., Davidson M., Nora R.M., and Davis K.L. Early response to clozapine in schizophrenia. Am J Psychiatry 151 (1994) 1817-1818
25. Umbricht D.S., Wirshing W.C., Wirshing D.A., McMeniman M., Schooler N.R., Marder S.R., et al. Clinical predictors of response to clozapine treatment in ambulatory patients with schizophrenia. J Clin Psychiatry 63 5 (2002) 420-424
26. Brill N., Reichenberg A., Rabinowitz J., Harary E., Lubin G., Davidson M., et al. Accuracy of self-reported premorbid functioning in schizophrenia. Schizophr Res 97 1-3 (2007) 103-108
27. van Winkel R., Myin-Germeys I., Delespaul P., Peuskens J., De Hert M., and van Os J. Premorbid IQ as a predictor for the course of IQ in first onset patients with schizophrenia: a 10-year follow-up study. Schizophr Res 88 1-3 (2006) 47-54