Osteopontin provides early proliferative drive and may be dependent upon aberrant c-myc signalling in murine intestinal tumours

Experimental and Molecular Pathology

Volumn 88, Issue 2, 2010, Pages 272-277

  Martinez, Cristina ^a   Churchman, Michael ^b   Freeman, Tom ^c   Ilyas, Mohammad ^d  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

C myc; Intestine; Osteopontin; Pea3; Tumourigenesis; Wnt signalling

Indexed keywords

BETA CATENIN; MYC PROTEIN; OSTEOPONTIN; TRANSCRIPTION FACTOR PEA3; WNT PROTEIN;

ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CARCINOGENESIS; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; INTESTINE TUMOR; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BETA CATENIN; CELL DIVISION; CELL LINE, TUMOR; CLONING, MOLECULAR; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; OSTEOPONTIN; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS P21(RAS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 77950626817     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2009.12.008     Document Type: Article

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