Silymarin suppress CD4+ T cell activation and proliferation: Effects on NF-κB activity and IL-2 production

Pharmacological Research

Volumn 61, Issue 5, 2010, Pages 405-409

  Gharagozloo, Marjan ^a   Velardi, Enrico ^b   Bruscoli, Stefano ^b   Agostini, Massimiliano ^b   Di Sante, Moises ^b   Donato, Valerio ^b   Amirghofran, Zahra ^c   Riccardi, Carlo ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF PERUGIA   (Italy)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

IL 2; NF B activation; Silymarin; T cell activation; T cell proliferation

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; SILYMARIN; SYNAPTOTAGMIN I;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; IN VITRO STUDY; INHIBITION KINETICS; LYMPHOCYTE PROLIFERATION; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANNEXIN A5; BIOTRANSFORMATION; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL PROLIFERATION; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGIC FACTORS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NF-KAPPA B; PROTEIN TRANSPORT; SILYMARIN; SPLEEN; TRANSCRIPTION FACTOR RELA;

EID: 77950626596     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2009.12.017     Document Type: Article

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