The role of photopheresis in the treatment of graft- versus-host disease

Current Oncology

Volumn 17, Issue 2, 2010, Pages 55-58

  Klassen, J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Acute GVHD; Anti inflammatory cytokines; Chronic GVHD; Graftversus host disease; GVHD; Hematopoietic stem cell transplantation; Immunomodulatory therapy; Photopheresis; Photosensitizing agent; Pro inflammatory cytokines; T regulatory cells; Targeted symptom assessment; Total skin score

Indexed keywords

CYTOKINE; PHOTOSENSITIZING AGENT;

ACUTE GRAFT VERSUS HOST DISEASE; APOPTOSIS; ARTICLE; CATHETER INFECTION; CATHETER OCCLUSION; CENTRAL VENOUS CATHETER; CHRONIC GRAFT VERSUS HOST DISEASE; DEEP VEIN THROMBOSIS; DISEASE SEVERITY; EQUIPMENT; EXTRACORPOREAL PHOTOPHERESIS; GRAFT VERSUS HOST REACTION; HUMAN; PATIENT SAFETY; PUVA; REGULATORY T LYMPHOCYTE; STENOSIS; TREATMENT DURATION; TREATMENT FAILURE; VASCULAR ACCESS;

EID: 77950591079     PISSN: None     EISSN: 17187729     Source Type: Journal    
DOI: 10.3747/co.v17i2.565     Document Type: Article

References (26)

1. Soiffer R. Immune modulation and chronic graft-versus-host disease. Bone Marrow Transplant 2008;42(suppl 1):S66-9.
2. Filipovich AH, Weisdorf D, Pavletic S, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005;11:945-56.
3. Li M, Sun K, Welniak LA, Murphy WJ. Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease. Expert Opin Pharmacother 2008;9:2305-16.
4. Martin PJ. Biology of chronic graft-versus-host disease: implications for a future therapeutic approach. Keio J Med 2008;57:177-83.
5. Edelson R, Berger C, Gasparro F, et al. Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results. N Engl J Med 1987;316:297-303.
6. Savill J, Dransfield I, Gregory C, Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002;2:965-75.
7. Lamioni A, Parisi F, Isacchi G, et al. The immunological effects of extracorporeal photopheresis unraveled: induction of tolerogenic dendritic cells in vitro and regulatory T cells in vivo. Transplantation 2005;79:846-50.
8. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving tgf-β, pge2, and paf. J Clin Invest 1998;101:890-8.
9. Maeda A, Schwarz A, Kernebeck K, et al. Intravenous infusion of syngeneic apoptotic cells by photopheresis induces antigen-specific regulatory T cells. J Immunol 2005;174:5968-76.
10. Gerner M, Hölig K, Wehner R, et al. Extracorporeal photopheresis efficiently impairs the proinflammatory capacity of human 6-sulfo LacNAc dendritic cells. Transplantation 2009;87:1134-9.
11. Biagi E, Di Biaso I, Leoni V, et al. Extracorporeal photochemotherapy is accompanied by increasing levels of circulating CD4+CD25+GITR+Foxp3+CD62L+ functional regulatory T-cells in patients with graft-versus-host disease. Transplantation 2007;84:31-9.
12. Gatza E, Rogers CE, Clouthier SG, et al. Extracorporeal photopheresis reverses experimental graft-versus-host disease through regulatory T cells. Blood 2008;112:1515-21.
13. Suchin KR, Cassin M, Washko R, et al. Extracorporeal photochemotherapy does not suppress T- or B-cell responses to novel or recall antigens. J Am Acad Dermatol 1999;41:980-6.
14. Scarisbrick JJ, Taylor P, Holtick U, et al. on behalf of the Photopheresis Expert Group. U.K. consensus statement on the use of extracorporeal photopheresis for treatment of cutaneous T-cell lymphoma and chronic graft-versus-host disease. Br J Dermatol 2008;158:659-78.
15. Kanold J, Merlin E, Halle P, et al. Photopheresis in pediatric graft-versus-host disease after allogeneic marrow transplantation: clinical practice guidelines based on field experience and review of the literature. Transfusion 2007;47:2276-89.
16. Marques MB, Tuncer HH. Photopheresis in solid organ transplant rejection. J Clin Apher 2006;21:72-7.
17. Bisaccia E, Vonderheid EC, Geskin L. Safety of a new, single, integrated, closed photopheresis system in patients with cutaneous T-cell lymphoma. Br J Dermatol 2009;161:167-9.
18. Hymes SR, Turner ML, Champlin RE, Couriel DR. Cutaneous manifestations of chronic graft-versus-host disease. Biol Blood Marrow Transplant 2006;12:1101-13.
19. Pavletic SZ, Martin P, Lee SJ, et al. Measuring therapeutic response in chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group report. Biol Blood Marrow Transplant 2006;12:252-66.
20. Greinix HT, Knobler RM, Worel N, et al. The effect of intensified extracorporeal photochemotherapy on long-term survival in patients with severe acute graft-versus-host disease. Haematologica 2006;91:405-8.
21. Foss FM, DiVenuti GM, Chin K, et al. Prospective study of extracorporeal photopheresis in steroid-refractory or steroidresistant extensive chronic graft-versus-host disease: analysis of response and survival incorporating prognostic factors. Bone Marrow Transplant 2005;35:1187-93.
22. Flowers ME, Apperley JF, van Besien K, et al. A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versushost disease. Blood 2008;112:2667-74. [Erratum in: Blood 2009;113:4478]
23. Griffith LM, Pavletic SZ, Lee SJ, Martin PJ, Schultz KR, Vogelsang GB. Chronic graft-versus-host disease-implementation of the National Institutes of Health Consensus Criteria for Clinical Trials. Biol Blood Marrow Transplant 2008;4:379-84.
24. Schultz KR, Miklos DB, Fowler D, et al. Toward biomarkers for chronic graft-versus-host disease: National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: III. Biomarker Working Group Report. Biol Blood Marrow Transplant 2006;12:126-37.
25. Demirkiran A, Hendrikx TK, Baan CC, van der Laan LJ. Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting? Transplantation 2008;85:783-9.
26. Barton GM. A calculated response: control of inflammation by the innate immune system. J Clin Invest 2008;118:413-20.