The immunological effects of extracorporeal photopheresis unraveled: Induction of tolerogenic dendritic cells in vitro and regulatory T cells in vivo

Transplantation

Volumn 79, Issue 7, 2005, Pages 846-850

  Lamioni, Andrea ^a   Parisi, Francesco ^a   Isacchi, Giancarlo ^a,b   Giorda, Ezio ^a   Di Cesare, Silvia ^b   Landolfo, Attilio ^a   Cenci, Francesco ^a   Bottazzo, Gian Franco ^a   Carsetti, Rita ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Apoptosis; Photopheresis; Regulatory T cells; Transplant rejection

Indexed keywords

CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADOLESCENT; ADULT; ARTICLE; CARDIAC GRAFT REJECTION; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; LUNG GRAFT REJECTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PUVA; SCHOOL CHILD; T LYMPHOCYTE;

ADOLESCENT; ADULT; APOPTOSIS; CHILD; DENDRITIC CELLS; HEART TRANSPLANTATION; HUMANS; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; LUNG TRANSPLANTATION; PHAGOCYTES; PHENOTYPE; PHOTOPHERESIS; T-LYMPHOCYTES;

EID: 17444430417     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000157278.02848.C7     Document Type: Article

References (18)

1. Russell-Jones R. Shedding light on photopheresis. Lancet 2001; 357: 820.
2. Berger CL, Xu AL, Hanlon D, et al. Induction of human tumor-loaded dendritic cells. Int J Cancer 2001; 91: 438.
3. Legitimo A, Consolini R, Di Stefano R, et al. Evaluation of the immunomodulatory mechanisms of photochemotherapy in transplantation. Transplant Proc 2001; 33: 2266.
4. Maccherini M, Diciolla F, Laghi Pasini F, et al. Photopheresis immunomodulation after heart transplantation. Transplant Proc 2001; 33: 1591.
5. Barr ML, Meiser BM, Eisen HJ, et al. Photopheresis for the prevention of rejection in cardiac transplantation. Photopheresis Transplantation Study Group. N Engl J Med 1998; 339: 1744.
6. Greinix HT, Volc-Platzer B, Rabitsch W, et al. Successful use of extracorporeal photochemotherapy in the treatment of severe acute and chronic graft-versus-host disease. Blood 1998; 92: 3098.
7. Gorgun G, Miller KB, Foss FM. Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease. Blood 2002; 100: 941.
8. Ludvigsson J, Samuelsson U, Ernerudh J, et al. Photopheresis at onset of type 1 diabetes: a randomised, double blind, placebo controlled trial. Arch Dis Child. 2001; 85: 149.
9. Rostami AM, Sater RA, Bird SJ, et al. A double-blind, placebo-controlled trial of extracorporeal photopheresis in chronic progressive multiple sclerosis. Mult Scler 1999; 5: 198.
10. Aubin F, Mousson C. Ultraviolet light-induced regulatory (suppressor) T cells: an approach for promoting induction of operational allograft tolerance? Transplantation 2004; 77: S29.
11. Jonuleit H, Schmitt E, Stassen M, et al. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001; 193: 1285.
12. Jonuleit H, Schmitt E, Kakirman H, et al. Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J Exp Med 2002; 196: 255.
13. Ferguson TA, Stuart PM, Herndon JM, Griffith TS. Apoptosis, tolerance, and regulatory T cells-old wine, new wineskins. Immunol Rev 2003; 193: 111.
14. Dent CL, Canter CE, Hirsch R, Balzer DT. Transplant coronary artery disease in pediatric heart transplant recipients. J Heart Lung Transplant 2000; 19: 240.
15. Boucek MM, Edwards LB, Keck BM, et al. The Registry of the International Society for Heart and Lung Transplantation: Fifth Official Pediatric Report - 2001 to 2002. J Heart Lung Transplant 2002; 21: 827.
16. Fehervari Z, Sakaguchi S. Development and function of CD25+CD4+ regulatory T cells. Curr Opin Immunol 2004; 16: 203.
17. Propato A, Cutrona G, Francavilla V, et al. Apoptotic cells overexpress vinculin and induce vinculin-specific cytotoxic T-cell cross-priming. Nat Med 2001; 7: 807.
18. Suchin KR, Cassin M, Washko R, et al. Extracorporeal photochemotherapy does not suppress T- or B-cell responses to novel or recall antigens. J Am Acad Dermatol 1999; 41: 980.