Predictors of the recurrence of hepatic encephalopathy in lactulose-treated patients

Alimentary Pharmacology and Therapeutics

Volumn 31, Issue 9, 2010, Pages 1012-1017

  Bajaj, J S ^a   Sanyal, A J ^a   Bell, D ^a   Gilles, H ^a   Heuman, D M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTULOSE; GASTROINTESTINAL AGENT;

ABDOMINAL PAIN; ADULT; ARTICLE; BLOATING; CONTROLLED STUDY; DEHYDRATION; DIARRHEA; DISEASE ASSOCIATION; DISEASE COURSE; DRUG DOSE TITRATION; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEPATIC ENCEPHALOPATHY; HUMAN; HYPONATREMIA; LIVER CIRRHOSIS; LIVER GRAFT; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; RECURRENT DISEASE; SEPSIS; SODIUM BLOOD LEVEL; TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT; ADOLESCENT; AGED; COMPARATIVE STUDY; COMPLICATION; MIDDLE AGED; RETROSPECTIVE STUDY; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; GASTROINTESTINAL AGENTS; HEPATIC ENCEPHALOPATHY; HUMANS; LACTULOSE; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; RECURRENCE; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 77950586321     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04257.x     Document Type: Article

References (22)

1. Poordad FF. Review article: the burden of hepatic encephalopathy. Aliment Pharmacol Ther 2007 25 (Suppl 1 3 9.
2. Bustamante J, Rimola A, Ventura PJ, et al. Prognostic significance of hepatic encephalopathy in patients with cirrhosis. J Hepatol 1999 30 : 890 895. (Pubitemid 29248991)
3. Sanyal AJ, Banas C, Sargeant C, et al. Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C. Hepatology 2006 43 : 682 689.
4. D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006 44 : 217 231. (Pubitemid 41772537)
5. Shawcross D, Jalan R. Dispelling myths in the treatment of hepatic encephalopathy. Lancet 2005 365 : 431 433. (Pubitemid 40179231)
6. Als-Nielsen B, Gluud LL, Gluud C. Non-absorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials. BMJ 2004 328 : 1046. (Pubitemid 38580827)
7. Stewart CA, Malinchoc M, Kim WR, Kamath PS. Hepatic encephalopathy as a predictor of survival in patients with end-stage liver disease. Liver Transpl 2007 13 : 1366 1371. (Pubitemid 47629568)
8. Garcia-Tsao G, Lim JK. Management and treatment of patients with cirrhosis and portal hypertension: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program. Am J Gastroenterol 2009 104 : 1802 1829.
9. Blanc P, Daures JP, Liautard J, et al. [Lactulose-neomycin combination versus placebo in the treatment of acute hepatic encephalopathy. Results of a randomized controlled trial]. Gastroenterol Clin Biol 1994 18 : 1063 1068.
10. Mullen KD, Amodio P, Morgan MY. Therapeutic studies in hepatic encephalopathy. Metab Brain Dis 2007 4 : 407 423. (Pubitemid 47624313)
11. Blei AT, Cordoba J. Hepatic Encephalopathy. Am J Gastroenterol 2001 96 : 1968 1976. (Pubitemid 32660887)
12. Leevy CB, Phillips JA. Hospitalizations during the use of rifaximin versus lactulose for the treatment of hepatic encephalopathy. Dig Dis Sci 2007 52 : 737 741. (Pubitemid 46303056)
13. Lanthier PL, Morgan MY. Lactitol in the treatment of chronic hepatic encephalopathy: an open comparison with lactulose. Gut 1985 26 : 415 420.
14. Kalaitzakis E, Bjornsson E. Lactulose treatment for hepatic encephalopathy, gastrointestinal symptoms, and health-related quality of life. Hepatology 2007 46 : 949 950 author reply 951. (Pubitemid 47436144)
15. Kalaitzakis E, Simren M, Olsson R, et al. Gastrointestinal symptoms in patients with liver cirrhosis: associations with nutritional status and health-related quality of life. Scand J Gastroenterol 2006 41 : 1464 1472. (Pubitemid 44764408)
16. Neff GW, Kemmer N, Zacharias VC, et al. Analysis of hospitalizations comparing rifaximin versus lactulose in the management of hepatic encephalopathy. Transplant Proc 2006 38 : 3552 3555. (Pubitemid 44908490)
17. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974 2 : 81 4.
18. Gines P, Schrier RW. Renal failure in cirrhosis. N Engl J Med 2009 361 : 1279 1290.
19. Guevara M, Baccaro ME, Torre A, et al. Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis. Am J Gastroenterol 2009 104 : 1382 1389.
20. Weissenborn K. Clinical Features of Hepatic Encephalopathy. Fourth ed.
21. Sharma BC, Sharma P, Agrawal A, Sarin SK. Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo. Gastroenterology 2009 137 : 885 891, 891 e1.
22. Hassanein T, Blei AT, Perry W, et al. Performance of the hepatic encephalopathy scoring algorithm in a clinical trial of patients with cirrhosis and severe hepatic encephalopathy. Am J Gastroenterol 2009 104 : 1392 1400.