Emergency contraception: Update and review

Seminars in Reproductive Medicine

Volumn 28, Issue 2, 2010, Pages 95-102

  Langston, Aileen ^a  

^a Department of Medicine   (United States)

Author keywords

Contraception; Levonorgestrel; Plan B; Postcoital

Indexed keywords

ESTROGEN; GESTAGEN; LEVONORGESTREL; MIFEPRISTONE;

EMERGENCY CONTRACEPTION; HUMAN; INTRAUTERINE CONTRACEPTIVE DEVICE; REVIEW; SEXUAL CRIME; SEXUAL INTERCOURSE;

CONTRACEPTION, POSTCOITAL; CONTRACEPTIVE AGENTS, FEMALE; CONTRACEPTIVES, ORAL, COMBINED; ETHINYL ESTRADIOL; FEMALE; HUMANS; INTRAUTERINE DEVICES, COPPER; LEVONORGESTREL; NORPREGNADIENES; PATIENT EDUCATION AS TOPIC; PREGNANCY; UNITED STATES;

EID: 77950538510     PISSN: 15268004     EISSN: 15264564     Source Type: Journal    
DOI: 10.1055/s-0030-1248133     Document Type: Review

References (88)

1. Finer L B., Henshaw S K. Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspect Sex Reprod Health 2006 38 (2) 90-96
2. Henshaw S K. Unintended pregnancy in the United States. Fam Plann Perspect 1998 30 (1) 24-29, 46
3. Practice Bulletin ACOG American College of Obstetricians and Gynecologists. ACOG Practice Bulletin. Clinical Management Guidelines for Obstetrician-Gynecologists, No. 69, December 2005 (replaces Practice Bulletin No. 25, March 2001). Emergency contraception. Obstet Gynecol 2005 106 (6) 1443-1452
4. AMA National Advisory Council on Violence and Abuse. Policy Compendium, Access to Emergency Contraception, 2008. Available at: www.ama.org Accessed September 15, 2009
5. Policy Statements ACEP. Management of the patient with the complaint of sexual assault. ACEP Policy Statements [Web site]. 2002; Policies of the national organization of emergency medicine practitioners in the United States. Available at: www.acep.org Accessed August 25, 2009
6. Harper C C., Ellertson C E. The emergency contraceptive pill: a survey of knowledge and attitudes among students at Princeton University. Am J Obstet Gynecol 1995 173 (5) 1438-1445
7. Cheng L, G?lmezoglu A M., Piaggio G, Ezcurra E, Van Look P F. Interventions for emergency contraception. Cochrane Database Syst Rev 2008 (2) CD001324
8. Ragland D, West D. Pharmacy students' knowledge, attitudes, and behaviors regarding emergency contraception. Am J Pharm Educ 2009 73 (2) 26
9. Trussell J, Stewart F, Guest F, Hatcher R A. Emergency contraceptive pills: a simple proposal to reduce unintended pregnancies. Fam Plann Perspect 1992 24 (6) 269-273
10. Van Look P F., von Hertzen H. Clinical uses of antiprogestogens. Hum Reprod Update 1995 1 (1) 19-34
11. Haddad L B., Nour N M. Unsafe abortion: unnecessary maternal mortality. Rev Obstet Gynecol 2009 2 (2) 122-126
12. Singh S. Hospital admissions resulting from unsafe abortion: estimates from 13 developing countries. Lancet 2006 368 (9550) 1887-1892
13. Governments worldwide put emergency contraception into women's hands; 2004. Available at: www.reproductiverights.org Accessed September 15, 2009
14. Glasier A. Emergency postcoital contraception. N Engl J Med 1997 337 (15) 1058-1064
15. Stewart F, Trussell J, Van Look P FA. Emergency contraception. In: Contraceptive Technology. 19th ed. New York, NY Ardent Media 2008 87-109
16. Ellertson C, Trussell J, Stewart F, Koenig J, Raymond E G., Shochet T. Emergency contraception. Semin Reprod Med 2001 19 (4) 323-330
17. Morris J M., Van Wagenen G. Compounds interfering with ovum implantation and development. 3. The role of estrogens. Am J Obstet Gynecol 1966 96 (6) 804-815
18. Yuzpe A A., Thurlow H J., Ramzy I, Leyshon J I. Post coital contraceptiona pilot study. J Reprod Med 1974 13 (2) 53-58
19. FDA approves generic prescription-only version of Plan B emergency contraceptive for women ages 17 and under; 2009. Available at: www.fda.gov/newsevents Accessed August 27, 2009
20. Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Task Force on Postovulatory Methods of Fertility Regulation. Lancet 1998 352 (9126) 428-433
21. Reports OPRR. Protection of Human Subjects. Code of Federal Regulations 45 CFR 46. National Institutes of Health 1983
22. Hughes E C., Committee on Terminology of the American College of Obstetricians and Gynecologists. Obstetric-Gynecologic Terminology. Philadelphia, PA F.A. Davis 1972
23. Durand M, del Carmen Cravioto M, Raymond E G. et al. On the mechanisms of action of short-term levonorgestrel administration in emergency contraception. Contraception 2001 64 (4) 227-234
24. Hapangama D, Glasier A F., Baird D T. The effects of peri-ovulatory administration of levonorgestrel on the menstrual cycle. Contraception 2001 63 (3) 123-129
25. Marions L, Hultenby K, Lindell I, Sun X, St?bi B, Gemzell Danielsson K. Emergency contraception with mifepristone and levonorgestrel: mechanism of action. Obstet Gynecol 2002 100 (1) 65-71
26. Marions L, Cekan S Z., Bygdeman M, Gemzell-Danielsson K. Effect of emergency contraception with levonorgestrel or mifepristone on ovarian function. Contraception 2004 69 (5) 373-377 (Pubitemid 38510327)
27. Trussell J, Ellertson C, von Hertzen H et al. Estimating the effectiveness of emergency contraceptive pills. Contraception 2003 67 (4) 259-265
28. Wilcox A J., Weinberg C R., Baird D D. Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby. N Engl J Med 1995 333 (23) 1517-1521
29. Trussell J, Raymond E G. Statistical evidence about the mechanism of action of the Yuzpe regimen of emergency contraception. Obstet Gynecol 1999 93 (5 Pt 2) 872-876 (Pubitemid 29197935)
30. Raymond E G., Lovely L P., Chen-Mok M, Sepp?l? M, Kurman R J., Lessey B A. Effect of the Yuzpe regimen of emergency contraception on markers of endometrial receptivity. Hum Reprod 2000 15 (11) 2351-2355
31. Taskin O, Brown R W., Young D C., Poindexter A N., Wiehle R D. High doses of oral contraceptives do not alter endometrial alpha 1 and alpha v beta 3 integrins in the late implantation window. Fertil Steril 1994 61 (5) 850-855
32. Hansen L B., Saseen J J., Teal S B. Levonorgestrel-only dosing strategies for emergency contraception. Pharmacotherapy 2007 27 (2) 278-284
33. Kunz G, Beil D, Deininger H, Wildt L, Leyendecker G. The dynamics of rapid sperm transport through the female genital tract: evidence from vaginal sonography of uterine peristalsis and hysterosalpingoscintigraphy. Hum Reprod 1996 11 (3) 627-632
34. Kesser? E, Garmendia F, Westphal N, Parada J. The hormonal and peripheral effects of d-norgestrel in postcoital contraception. Contraception 1974 10 (4) 411-424
35. Hamoda H, Ashok P W., Stalder C, Flett G M., Kennedy E, Templeton A. A randomized trial of mifepristone (10 mg) and levonorgestrel for emergency contraception. Obstet Gynecol 2004 104 (6) 1307-1313 (Pubitemid 40458728)
36. von Hertzen H, Piaggio G, Ding J et al, WHO Research Group on Post-ovulatory Methods of Fertility Regulation. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet 2002 360 (9348) 1803-1810
37. Ngai S W., Fan S, Li S et al. A randomized trial to compare 24 h versus 12 h double dose regimen of levonorgestrel for emergency contraception. Hum Reprod 2005 20 (1) 307-311
38. Fincham J E., Harris C E., Fassett W E., Richards W. Over-the-counter availability of Plan B emergency contraception: further discussion and commentary. Ann Pharmacother 2005 39 (2) 346-351
39. State Policies in Brief. Emergency contraception. State policies in brief. Description of state laws and policies regarding emergency contraception in the United States. Available at: www.guttmacher.org Accessed August 25, 2009
40. Plan B. OneStep Prescribing Information; 2009. Available at: www.accessdata.fda.gov/drugsatfda-docs/label/2009/021998lbl.pdf Accessed October 16, 2009
41. ACOG statement on Single-Dose EC Reformulation. 2009. Available at: www.acog.org/from-home/publications/press-releases/nr07-15-09.cfm Accessed October 15, 2009
42. Ho P C., Kwan M S. A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception. Hum Reprod 1993 8 (3) 389-392
43. Arowojolu A O., Okewole I A., Adekunle A O. Comparative evaluation of the effectiveness and safety of two regimens of levonorgestrel for emergency contraception in Nigerians. Contraception 2002 66 (4) 269-273
44. Devoto L, Fuentes A, Palomino A et al. Pharmacokinetics and endometrial tissue levels of levonorgestrel after administration of a single 1.5-mg dose by the oral and vaginal route. Fertil Steril 2005 84 (1) 46-51
45. Yuzpe A A., Lancee W J. Ethinylestradiol and dl-norgestrel as a postcoital contraceptive. Fertil Steril 1977 28 (9) 932-936
46. Van Santen M R., Haspels A A. Interception II: postcoital low-dose estrogens and norgestrel combination in 633 women. Contraception 1985 31 (3) 275-293
47. Percival-Smith R K., Abercrombie B. Postcoital contraception with dl-norgestrel/ethinyl estradiol combination: six years experience in a student medical clinic. Contraception 1987 36 (3) 287-293
48. Rodrigues I, Grou F, Joly J. Effectiveness of emergency contraceptive pills between 72 and 120 hours after unprotected sexual intercourse. Am J Obstet Gynecol 2001 184 (4) 531-537
49. First emergency contraceptive product hits U.S. market shelves. Contracept Technol Update 1998 19 (11) 141-143
50. And then there was one: Barr withdraws Preven. Contraceptive Technology Update, Executive Summary; 2004. Available at: www.accessmylibrary.com/article/ print/1G1-120976676 Accessed September 9, 2009
51. Trussell J, Rodr?guez G, Ellertson C. New estimates of the effectiveness of the Yuzpe regimen of emergency contraception. Contraception 1998 57 (6) 363-369
52. Trussell J, Rodr?guez G, Ellertson C. Updated estimates of the effectiveness of the Yuzpe regimen of emergency contraception. Contraception 1999 59 (3) 147-151 (Pubitemid 29277543)
53. Ragan R E., Rock R W., Buck H W. Metoclopramide pretreatment attenuates emergency contraceptive-associated nausea. Am J Obstet Gynecol 2003 188 (2) 330-333
54. Emergency Contraception. 2005. www.who.int/mediacentre/factsheets/fs244/ en/print.html Accessed September 15, 2009
55. Prescription drug products: certain combined oral contraceptives for use as postcoital emergency contraception. Fed Regist 1997 62 8609
56. Webb A, Taberner D. Clotting factors after emergency contraception. Adv Contracept 1993 9 (1) 75-82
57. Balter M. Profile. For father of abortion drug, vindication at last. Science 2000 290 (5489) 39
58. Gemzell-Danielsson K, Marions L. Mechanisms of action of mifepristone and levonorgestrel when used for emergency contraception. Hum Reprod Update 2004 10 (4) 341-348 (Pubitemid 38997071)
59. Rowlands S. New technologies in contraception. BJOG 2009 116 (2) 230-239
60. Comparison of three single doses of mifepristone as emergency contraception: a randomised trial. Task Force on Postovulatory Methods of Fertility Regulation. Lancet 1999 353 (9154) 697-702
61. Lippes J, Malik T, Tatum H J. The postcoital copper-T. Adv Plan Parent 1976 11 (1) 24-29
62. Faculty of Family Planning and Reproductive Health Care Clinical Effectiveness Unit. FFPRHC Guidance: Emergency contraception (April 2003). J Fam Plann Reprod Health Care 2003 29 (2) 9-16
63. Grimes D A., Schulz K F. Antibiotic prophylaxis for intrauterine contraceptive device insertion. Cochrane Database Syst Rev 2001 (2) CD001327
64. Penney G, Brechin S, de Souza A et al, Faculty of Family Planning and Reproductive Health Care Clinical Effectiveness Unit. FFPRHC Guidance (January 2004). The copper intrauterine device as long-term contraception. J Fam Plann Reprod Health Care 2004 30 (1) 29-41, quiz 42
65. Segal S J., Alvarez-Sanchez F, Adejuwon C A., Brache de Mejia V, Leon P, Faundes A. Absence of chorionic gonadotropin in sera of women who use intrauterine devices. Fertil Steril 1985 44 (2) 214-218
66. Stanford J B., Mikolajczyk R T. Mechanisms of action of intrauterine devices: update and estimation of postfertilization effects. Am J Obstet Gynecol 2002 187 (6) 1699-1708
67. Askalani A H., Al-Senity A M., Al-Agizy H M., Salam H I., Al-Masry G I., El-Sadek S M. Evaluation of copper T-200 as a post-coital contraceptive. Egyptian J Obstet Gynecol 1987 13 63-66
68. Trussell J. Contraceptive efficacy. Arch Dermatol 1995 131 (9) 1064-1068
69. Grimes D A., Lopez L M., Manion C, Schulz K F. Cochrane systematic reviews of IUD trials: lessons learned. Contraception 2007 75 (6, suppl) S55-S59
70. Criminal Victimization in the United StatesStatistical Tables. Data from National Crime Victimization Survey presented in tables. Available at: www.ojp.usdoj.gov/bjs/abstract/cvusst.htm Accessed September 17, 2009
71. Kaplan D W., Feinstein R A., Fisher M M. et al, Committee on Adolescence. Care of the adolescent sexual assault victim. Pediatrics 2001 107 (6) 1476-1479
72. Kavanaugh M L., Saladino R A., Gold M A. Emergency contraception services for adolescents: a National Survey of Children's Hospital Emergency Department Directors. J Pediatr Adolesc Gynecol 2009 22 (2) 111-119
73. Patel A, Panchal H, Piotrowski Z H., Patel D. Comprehensive medical care for victims of sexual assault: a survey of Illinois hospital emergency departments. Contraception 2008 77 (6) 426-430
74. Espey E, Ogburn T, Leeman L, Buchen E, Angeli E, Qualls C. Compliance with mandated emergency contraception in New Mexico emergency departments. J Womens Health (Larchmt) 2009 18 (5) 619-623
75. Rosenberg K D., Demunter J K., Liu J. Emergency contraception in emergency departments in Oregon, 2003. Am J Public Health 2005 95 (8) 1453-1457
76. Woodell A T., Bowling J M., Moracco K E., Reed M L. Emergency contraception for sexual assault victims in North Carolina emergency departments. N C Med J 2007 68 (6) 399-403
77. Emergency contraception for rape survivors; 2007. Available at: http://reproductiverights.org/en/document/emergency-contraception-for-rape- survivors Accessed September 17, 2009
78. Committee for medicinal products for human use summary of positive opinion for Ellaone Doc.Ref.EMEA/CHMP/167750/2009. Available at: www.emea.europa.eu Accessed September 16, 2009
79. International Consortium for Emergency Contraception. 2009. Available at: www.cecinfo.org/inidex.php Accessed September 16, 2009
80. Creinin M D., Schlaff W, Archer D F. et al. Progesterone receptor modulator for emergency contraception: a randomized controlled trial. Obstet Gynecol 2006 108 (5) 1089-1097
81. Polis C B., Schaffer K, Blanchard K, Glasier A, Harper C C., Grimes D A. Advance provision of emergency contraception for pregnancy prevention (full review). Cochrane Database Syst Rev 2007 (2) CD005497
82. National Survey of Women About Their Sexual Health: Take charge of your sexual health. 2003. Available at: http://www.kff.org/womenshealth/3341-index. cfm Accessed September 15, 2009
83. Kavanaugh M L., Schwarz E B. Counseling about and use of emergency contraception in the United States. Perspect Sex Reprod Health 2008 40 (2) 81-86
84. Rocca C H., Schwarz E B., Stewart F H., Darney P D., Raine T R., Harper C C. Beyond access: acceptability, use and nonuse of emergency contraception among young women. Am J Obstet Gynecol 2007 196 (1) 21-26
85. Raymond E G., Trussell J, Polis C B. Population effect of increased access to emergency contraceptive pills: a systematic review. Obstet Gynecol 2007 109 (1) 181-188
86. Brown S S., Eisenberg L, Institute of Medicine. (U.S.) Committee on Unintended Pregnancy. The Best Intentions: Unintended Pregnancy and the Well-Being of Children and Families. Washington, DC National Academy Press 1995
87. Turok D K., Simonsen S E., Marshall N. Trends in levonorgestrel emergency contraception use, births, and abortions: the Utah experience. Medscape J Med 2009 11 (1) 30
88. Paraguard Product Information. Pharmaceutical product commercial Web site. Available at: www.paraguard.com Accessed September 16, 2009