Shorter telomeres may indicate dementia status in older individuals with Down syndrome

Neurobiology of Aging

Volumn 31, Issue 5, 2010, Pages 765-771

  Jenkins, Edmund C ^a   Ye, Lingling ^a   Gu, Hong ^a   Ni, Samantha A ^a   Velinov, Milen ^a   Pang, Deborah ^a,b   Krinsky McHale, Sharon J ^a   Zigman, Warren B ^a   Schupf, Nicole ^a,b   Silverman, Wayne P ^a,c  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dementia; Down syndrome; FISH; Individual chromosomes 21, 1, 2, 16; Interphase; Metaphase; Mild cognitive impairment; PNA; Telomere shortening

Indexed keywords

APOLIPOPROTEIN E;

ADULT; AGED; ARTICLE; CHROMOSOME 1; CHROMOSOME 16; CHROMOSOME 2; CHROMOSOME 21; CHROMOSOME ANALYSIS; DEMENTIA; DISEASE ASSOCIATION; DISEASE SEVERITY; DOWN SYNDROME; FEMALE; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; METAPHASE; MILD COGNITIVE IMPAIRMENT; PRIORITY JOURNAL; T LYMPHOCYTE; TELOMERE;

AGED; APOLIPOPROTEINS E; CHROMOSOMES, HUMAN, PAIR 21; DEMENTIA; DOWN SYNDROME; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; T-LYMPHOCYTES; TELOMERE;

EID: 77950535729     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2008.06.001     Document Type: Article

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