Pharmacological validation of a telemetric model for the measurement of bronchoconstriction in conscious rats

Journal of Pharmacological and Toxicological Methods

Volumn 61, Issue 2, 2010, Pages 219-229

  Ewart, Lorna C ^a   Haley, Michael ^a,b   Bickerton, Sue ^a   Bright, Jonathan ^a   Elliott, Katherine ^a   McCarthy, Alan ^a   Williams, Lisa ^a   Ricketts, Sally Ann ^a   Holland, Tom ^a   Valentin, Jean Pierre ^a  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Bronchoconstriction; Conscious; Head out plethysmography; Intrapleural pressure; Methods; Rat; Respiratory assessment; Telemetry

Indexed keywords

ADENOSINE 5' (N ETHYLCARBOXAMIDE); METHACHOLINE;

AIRWAY RESISTANCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY PLETHYSMOGRAPHY; BRONCHOSPASM; CONCENTRATION (PARAMETERS); CONSCIOUSNESS; CONTROLLED STUDY; LUNG VENTILATION; MALE; NONHUMAN; RAT; TELEMETRY; THORAX PRESSURE; VALIDATION STUDY;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); AIRWAY RESISTANCE; ANESTHESIA; ANIMALS; BRONCHOCONSTRICTOR AGENTS; CATHETERIZATION; CONSCIOUSNESS; MALE; METHACHOLINE CHLORIDE; MUSCARINIC AGONISTS; PLETHYSMOGRAPHY, WHOLE BODY; PLEURA; PRESSURE; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; REPRODUCIBILITY OF RESULTS; TELEMETRY;

ANIMALIA; RATTUS;

EID: 77950533314     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.02.008     Document Type: Article

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