-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., and Thun M.J. Cancer statistics, 2008. CA Cancer J. Clin. 58 (2008) 71-96
-
(2008)
CA Cancer J. Clin.
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
2
-
-
0036817842
-
Adjuvant therapy of cancers of the colon and rectum
-
Saltz L.B., and Minsky B. Adjuvant therapy of cancers of the colon and rectum. Surg. Clin. North Am. 82 (2002) 1035-1058
-
(2002)
Surg. Clin. North Am.
, vol.82
, pp. 1035-1058
-
-
Saltz, L.B.1
Minsky, B.2
-
3
-
-
44849106090
-
Induction of genetic instability by gain-of-function p53 cancer mutants
-
Xu Y. Induction of genetic instability by gain-of-function p53 cancer mutants. Oncogene 27 (2008) 3501-3507
-
(2008)
Oncogene
, vol.27
, pp. 3501-3507
-
-
Xu, Y.1
-
6
-
-
32544444894
-
Rosiglitazone inhibits endothelial proliferation and angiogenesis
-
Sheu W.H., Ou H.C., Chou F.P., Lin T.M., and Yang C.H. Rosiglitazone inhibits endothelial proliferation and angiogenesis. Life Sci. 78 (2006) 1520-1528
-
(2006)
Life Sci.
, vol.78
, pp. 1520-1528
-
-
Sheu, W.H.1
Ou, H.C.2
Chou, F.P.3
Lin, T.M.4
Yang, C.H.5
-
7
-
-
41149138254
-
Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3
-
Magenta G., Borenstein X., Rolando R., and Jasnis M.A. Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3. BMC Cancer 8 (2008) 47
-
(2008)
BMC Cancer
, vol.8
, pp. 47
-
-
Magenta, G.1
Borenstein, X.2
Rolando, R.3
Jasnis, M.A.4
-
8
-
-
58149178162
-
Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin
-
Girnun G.D., Chen L., Silvaggi J., Drapkin R., Chirieac L.R., Padera R.F., Upadhyay R., Vafai S.B., Weissleder R., Mahmood U., Naseri E., Buckley S., Li D., Force J., McNamara K., Demetri G., Spiegelman B.M., and Wong K.K. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin. Cancer Res. 14 (2008) 6478-6486
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6478-6486
-
-
Girnun, G.D.1
Chen, L.2
Silvaggi, J.3
Drapkin, R.4
Chirieac, L.R.5
Padera, R.F.6
Upadhyay, R.7
Vafai, S.B.8
Weissleder, R.9
Mahmood, U.10
Naseri, E.11
Buckley, S.12
Li, D.13
Force, J.14
McNamara, K.15
Demetri, G.16
Spiegelman, B.M.17
Wong, K.K.18
-
9
-
-
34247626779
-
Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma
-
Zhang Y.Q., Tang X.Q., Sun L., Dong L., Qin Y., Liu H.Q., Xia H., and Cao J.G. Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma. World J. Gastroenterol. 13 (2007) 1534-1540
-
(2007)
World J. Gastroenterol.
, vol.13
, pp. 1534-1540
-
-
Zhang, Y.Q.1
Tang, X.Q.2
Sun, L.3
Dong, L.4
Qin, Y.5
Liu, H.Q.6
Xia, H.7
Cao, J.G.8
-
10
-
-
39949085436
-
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
-
Kim Y.H., Jung E.M., Lee T.J., Kim S.H., Choi Y.H., Park J.W., Choi K.S., and Kwon T.K. Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic. Biol. Med. 44 (2008) 1055-1068
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 1055-1068
-
-
Kim, Y.H.1
Jung, E.M.2
Lee, T.J.3
Kim, S.H.4
Choi, Y.H.5
Park, J.W.6
Choi, K.S.7
Kwon, T.K.8
-
11
-
-
20044372348
-
Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest
-
Lu M., Kwan T., Yu C., Chen F., Freedman B., Schafer J.M., Lee E.J., Jameson J.L., Jordan V.C., and Cryns V.L. Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. J. Biol. Chem. 280 (2005) 6742-6751
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6742-6751
-
-
Lu, M.1
Kwan, T.2
Yu, C.3
Chen, F.4
Freedman, B.5
Schafer, J.M.6
Lee, E.J.7
Jameson, J.L.8
Jordan, V.C.9
Cryns, V.L.10
-
12
-
-
25844510796
-
Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity
-
Chen W.C., Lin M.S., and Bai X. Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity. Chin. Med. J. (Engl.) 118 (2005) 1477-1481
-
(2005)
Chin. Med. J. (Engl.)
, vol.118
, pp. 1477-1481
-
-
Chen, W.C.1
Lin, M.S.2
Bai, X.3
-
13
-
-
20444410811
-
Peroxisome proliferator-activated receptor gamma ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines
-
Yang F.G., Zhang Z.W., Xin D.Q., Shi C.J., Wu J.P., Guo Y.L., and Guan Y.F. Peroxisome proliferator-activated receptor gamma ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines. Acta Pharmacol. Sin. 26 (2005) 753-761
-
(2005)
Acta Pharmacol. Sin.
, vol.26
, pp. 753-761
-
-
Yang, F.G.1
Zhang, Z.W.2
Xin, D.Q.3
Shi, C.J.4
Wu, J.P.5
Guo, Y.L.6
Guan, Y.F.7
-
14
-
-
45749132986
-
Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition
-
Fuhrman C.B., Kilgore J., LaCoursiere Y.D., Lee C.M., Milash B.A., Soisson A.P., and Zempolich K.A. Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition. Gynecol. Oncol. 110 (2008) 93-98
-
(2008)
Gynecol. Oncol.
, vol.110
, pp. 93-98
-
-
Fuhrman, C.B.1
Kilgore, J.2
LaCoursiere, Y.D.3
Lee, C.M.4
Milash, B.A.5
Soisson, A.P.6
Zempolich, K.A.7
-
15
-
-
39749129748
-
Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity
-
Tanaka T., Munshi A., Brooks C., Liu J., Hobbs M.L., and Meyn R.E. Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity. Clin. Cancer Res. 14 (2008) 1266-1273
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 1266-1273
-
-
Tanaka, T.1
Munshi, A.2
Brooks, C.3
Liu, J.4
Hobbs, M.L.5
Meyn, R.E.6
-
16
-
-
0038519961
-
Enhancement of radiation response by roscovitine in human breast carcinoma in vitro and in vivo
-
Maggiorella L., Deutsch E., Frascogna V., Chavaudra N., Jeanson L., Milliat F., Eschwege F., and Bourhis J. Enhancement of radiation response by roscovitine in human breast carcinoma in vitro and in vivo. Cancer Res. 63 (2003) 2513-2517
-
(2003)
Cancer Res.
, vol.63
, pp. 2513-2517
-
-
Maggiorella, L.1
Deutsch, E.2
Frascogna, V.3
Chavaudra, N.4
Jeanson, L.5
Milliat, F.6
Eschwege, F.7
Bourhis, J.8
-
17
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., and Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273 (1998) 5858-5868
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
18
-
-
44449170822
-
Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells
-
Chiu S.J., Chao J.I., Lee Y.J., and Hsu T.S. Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells. Toxicol. Lett. 179 (2008) 63-70
-
(2008)
Toxicol. Lett.
, vol.179
, pp. 63-70
-
-
Chiu, S.J.1
Chao, J.I.2
Lee, Y.J.3
Hsu, T.S.4
-
19
-
-
33746618049
-
gammaH2AX as a checkpoint maintenance signal
-
Downey M., and Durocher D. gammaH2AX as a checkpoint maintenance signal. Cell Cycle 5 (2006) 1376-1381
-
(2006)
Cell Cycle
, vol.5
, pp. 1376-1381
-
-
Downey, M.1
Durocher, D.2
-
20
-
-
31444445458
-
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery
-
Keogh M.C., Kim J.A., Downey M., Fillingham J., Chowdhury D., Harrison J.C., Onishi M., Datta N., Galicia S., Emili A., Lieberman J., Shen X., Buratowski S., Haber J.E., Durocher D., Greenblatt J.F., and Krogan N.J. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 439 (2006) 497-501
-
(2006)
Nature
, vol.439
, pp. 497-501
-
-
Keogh, M.C.1
Kim, J.A.2
Downey, M.3
Fillingham, J.4
Chowdhury, D.5
Harrison, J.C.6
Onishi, M.7
Datta, N.8
Galicia, S.9
Emili, A.10
Lieberman, J.11
Shen, X.12
Buratowski, S.13
Haber, J.E.14
Durocher, D.15
Greenblatt, J.F.16
Krogan, N.J.17
-
21
-
-
34147190965
-
Radiation-induced cell signaling: inside-out and outside-in
-
Valerie K., Yacoub A., Hagan M.P., Curiel D.T., Fisher P.B., Grant S., and Dent P. Radiation-induced cell signaling: inside-out and outside-in. Mol. Cancer Ther. 6 (2007) 789-801
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 789-801
-
-
Valerie, K.1
Yacoub, A.2
Hagan, M.P.3
Curiel, D.T.4
Fisher, P.B.5
Grant, S.6
Dent, P.7
-
22
-
-
70449515802
-
Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
-
Li H.F., Kim J.S., and Waldman T. Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells. Radiat. Oncol. 4 (2009) 43
-
(2009)
Radiat. Oncol.
, vol.4
, pp. 43
-
-
Li, H.F.1
Kim, J.S.2
Waldman, T.3
-
23
-
-
67849083376
-
The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer
-
Schuurbiers O.C., Kaanders J.H., van der Heijden H.F., Dekhuijzen R.P., Oyen W.J., and Bussink J. The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer. J. Thorac. Oncol. 4 (2009) 761-767
-
(2009)
J. Thorac. Oncol.
, vol.4
, pp. 761-767
-
-
Schuurbiers, O.C.1
Kaanders, J.H.2
van der Heijden, H.F.3
Dekhuijzen, R.P.4
Oyen, W.J.5
Bussink, J.6
-
24
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman J.A., Luo J., and Cantley L.C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7 (2006) 606-619
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
25
-
-
0141757460
-
MAPK pathways in radiation responses
-
Dent P., Yacoub A., Fisher P.B., Hagan M.P., and Grant S. MAPK pathways in radiation responses. Oncogene 22 (2003) 5885-5896
-
(2003)
Oncogene
, vol.22
, pp. 5885-5896
-
-
Dent, P.1
Yacoub, A.2
Fisher, P.B.3
Hagan, M.P.4
Grant, S.5
-
26
-
-
0043032869
-
Dominant-negative cAMP-responsive element-binding protein inhibits proliferating cell nuclear antigen and DNA repair leading to increased cellular radiosensitivity
-
Amorino G.P., Mikkelsen R.B., Valerie K., and Schmidt-Ullrich R.K. Dominant-negative cAMP-responsive element-binding protein inhibits proliferating cell nuclear antigen and DNA repair leading to increased cellular radiosensitivity. J. Biol. Chem. 278 (2003) 29394-29399
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29394-29399
-
-
Amorino, G.P.1
Mikkelsen, R.B.2
Valerie, K.3
Schmidt-Ullrich, R.K.4
-
27
-
-
3042661957
-
Role of cell cycle in mediating sensitivity to radiotherapy
-
Pawlik T.M., and Keyomarsi K. Role of cell cycle in mediating sensitivity to radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 59 (2004) 928-942
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.59
, pp. 928-942
-
-
Pawlik, T.M.1
Keyomarsi, K.2
-
28
-
-
57149136324
-
GammaH2AX and cancer
-
Bonner W.M., Redon C.E., Dickey J.S., Nakamura A.J., Sedelnikova O.A., Solier S., and Pommier Y. GammaH2AX and cancer. Nat. Rev. Cancer 8 (2008) 957-967
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 957-967
-
-
Bonner, W.M.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Sedelnikova, O.A.5
Solier, S.6
Pommier, Y.7
-
29
-
-
34547765906
-
Rosiglitazone sensitizes MDA-MB-231 breast cancer cells to anti-tumour effects of tumour necrosis factor-alpha, CH11 and CYC202
-
Mody M., Dharker N., Bloomston M., Wang P.S., Chou F.S., Glickman T.S., McCaffrey T., Yang Z., Pumfery A., Lee D., Ringel M.D., and Pinzone J.J. Rosiglitazone sensitizes MDA-MB-231 breast cancer cells to anti-tumour effects of tumour necrosis factor-alpha, CH11 and CYC202. Endocr. Relat. Cancer 14 (2007) 305-315
-
(2007)
Endocr. Relat. Cancer
, vol.14
, pp. 305-315
-
-
Mody, M.1
Dharker, N.2
Bloomston, M.3
Wang, P.S.4
Chou, F.S.5
Glickman, T.S.6
McCaffrey, T.7
Yang, Z.8
Pumfery, A.9
Lee, D.10
Ringel, M.D.11
Pinzone, J.J.12
-
30
-
-
65549166721
-
Rosiglitazone and PPAR-gamma overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins
-
Wu J.S., Lin T.N., and Wu K.K. Rosiglitazone and PPAR-gamma overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins. J. Cell. Physiol. 220 (2009) 58-71
-
(2009)
J. Cell. Physiol.
, vol.220
, pp. 58-71
-
-
Wu, J.S.1
Lin, T.N.2
Wu, K.K.3
-
31
-
-
62649096776
-
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation
-
Wu J.S., Cheung W.M., Tsai Y.S., Chen Y.T., Fong W.H., Tsai H.D., Chen Y.C., Liou J.Y., Shyue S.K., Chen J.J., Chen Y.E., Maeda N., Wu K.K., and Lin T.N. Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation. Circulation 119 (2009) 1124-1134
-
(2009)
Circulation
, vol.119
, pp. 1124-1134
-
-
Wu, J.S.1
Cheung, W.M.2
Tsai, Y.S.3
Chen, Y.T.4
Fong, W.H.5
Tsai, H.D.6
Chen, Y.C.7
Liou, J.Y.8
Shyue, S.K.9
Chen, J.J.10
Chen, Y.E.11
Maeda, N.12
Wu, K.K.13
Lin, T.N.14
-
32
-
-
0034644506
-
Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF
-
Ries S., Biederer C., Woods D., Shifman O., Shirasawa S., Sasazuki T., McMahon M., Oren M., and McCormick F. Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF. Cell 103 (2000) 321-330
-
(2000)
Cell
, vol.103
, pp. 321-330
-
-
Ries, S.1
Biederer, C.2
Woods, D.3
Shifman, O.4
Shirasawa, S.5
Sasazuki, T.6
McMahon, M.7
Oren, M.8
McCormick, F.9
-
33
-
-
0036718590
-
MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells
-
Shonai T., Adachi M., Sakata K., Takekawa M., Endo T., Imai K., and Hareyama M. MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells. Cell Death Differ. 9 (2002) 963-971
-
(2002)
Cell Death Differ.
, vol.9
, pp. 963-971
-
-
Shonai, T.1
Adachi, M.2
Sakata, K.3
Takekawa, M.4
Endo, T.5
Imai, K.6
Hareyama, M.7
-
34
-
-
68549116985
-
A critical role for AKT activation in protecting cells from ionizing radiation-induced apoptosis and the regulation of acinus gene expression
-
Park H.S., Yun Y., Kim C.S., Yang K.H., Jeong M., Ahn S.K., Jin Y.W., and Nam S.Y. A critical role for AKT activation in protecting cells from ionizing radiation-induced apoptosis and the regulation of acinus gene expression. Eur. J. Cell. Biol. 88 (2009) 563-575
-
(2009)
Eur. J. Cell. Biol.
, vol.88
, pp. 563-575
-
-
Park, H.S.1
Yun, Y.2
Kim, C.S.3
Yang, K.H.4
Jeong, M.5
Ahn, S.K.6
Jin, Y.W.7
Nam, S.Y.8
-
35
-
-
34249339801
-
Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells
-
Cao L.Q., Chen X.L., Wang Q., Huang X.H., Zhen M.C., Zhang L.J., Li W., and Bi J. Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells. Acta Pharmacol. Sin. 28 (2007) 879-887
-
(2007)
Acta Pharmacol. Sin.
, vol.28
, pp. 879-887
-
-
Cao, L.Q.1
Chen, X.L.2
Wang, Q.3
Huang, X.H.4
Zhen, M.C.5
Zhang, L.J.6
Li, W.7
Bi, J.8
-
36
-
-
0038281227
-
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002
-
Gupta A.K., Cerniglia G.J., Mick R., Ahmed M.S., Bakanauskas V.J., Muschel R.J., and McKenna W.G. Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. Int. J. Radiat. Oncol. Biol. Phys. 56 (2003) 846-853
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.56
, pp. 846-853
-
-
Gupta, A.K.1
Cerniglia, G.J.2
Mick, R.3
Ahmed, M.S.4
Bakanauskas, V.J.5
Muschel, R.J.6
McKenna, W.G.7
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