메뉴 건너뛰기




Volumn 84, Issue 8, 2010, Pages 3962-3973

A novel inhibitor of the NF-κB signaling pathway encoded by the parapoxvirus orf virus

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN P65; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN ORFV024; CHEMOKINE; I KAPPA B; I KAPPA B KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; VIRULENCE FACTOR;

EID: 77950507119     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02291-09     Document Type: Article
Times cited : (56)

References (70)
  • 2
    • 0036328156 scopus 로고    scopus 로고
    • The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence
    • Bartlett, N., J. A. Symons, D. C. Tscharke, and G. L. Smith. 2002. The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence. J. Gen. Virol. 83: 1965-1976.
    • (2002) J. Gen. Virol. , vol.83 , pp. 1965-1976
    • Bartlett, N.1    Symons, J.A.2    Tscharke, D.C.3    Smith, G.L.4
  • 4
    • 11244285329 scopus 로고    scopus 로고
    • Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-alpha, IKKbeta, IKKepsilon, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
    • Buss, H., A. Dorrie, M. L. Schmitz, E. Hoffmann, K. Resch, and M. Kracht. 2004. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-alpha, IKKbeta, IKKepsilon, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. J. Biol. Chem. 279: 55633-55643.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55633-55643
    • Buss, H.1    Dorrie, A.2    Schmitz, M.L.3    Hoffmann, E.4    Resch, K.5    Kracht, M.6
  • 5
    • 0027392838 scopus 로고
    • Principles of paramunization. Option and limits in veterinary medicine
    • Buttner, M. 1993. Principles of paramunization. Option and limits in veterinary medicine. Comp. Immunol. Microbiol. Infect. Dis. 16: 1-10.
    • (1993) Comp. Immunol. Microbiol. Infect. Dis. , vol.16 , pp. 1-10
    • Buttner, M.1
  • 10
    • 33744818439 scopus 로고    scopus 로고
    • Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor
    • Chen, R. A., N. Jacobs, and G. L. Smith. 2006. Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor. J. Gen. Virol. 87: 1451-1458.
    • (2006) J. Gen. Virol. , vol.87 , pp. 1451-1458
    • Chen, R.A.1    Jacobs, N.2    Smith, G.L.3
  • 12
    • 33144469269 scopus 로고    scopus 로고
    • Recognition of vaccinia virusinfected cells by human natural killer cells depends on natural cytotoxicity receptors
    • Chisholm, S. E., and H. T. Reyburn. 2006. Recognition of vaccinia virusinfected cells by human natural killer cells depends on natural cytotoxicity receptors. J. Virol. 80: 2225-2233.
    • (2006) J. Virol. , vol.80 , pp. 2225-2233
    • Chisholm, S.E.1    Reyburn, H.T.2
  • 15
    • 4344600796 scopus 로고    scopus 로고
    • Poxvirus protein N1L targets the I-κB kinase complex, inhibits signaling to NF-κB by the tumor necrosis factor superfamily of receptors, and inhibits NF-κB and IRF3 signaling by Toll-like receptors
    • DiPerna, G., J. Stack, A. G. Bowie, A. Boyd, G. Kotwal, Z. Zhang, S. Arvikar, E. Latz, K. A. Fitzgerald, and W. L. Marshall. 2004. Poxvirus protein N1L targets the I-κB kinase complex, inhibits signaling to NF-κB by the tumor necrosis factor superfamily of receptors, and inhibits NF-κB and IRF3 signaling by Toll-like receptors. J. Biol. Chem. 279: 36570-36578.
    • (2004) J. Biol. Chem. , vol.279 , pp. 36570-36578
    • DiPerna, G.1    Stack, J.2    Bowie, A.G.3    Boyd, A.4    Kotwal, G.5    Zhang, Z.6    Arvikar, S.7    Latz, E.8    Fitzgerald, K.A.9    Marshall, W.L.10
  • 16
    • 0037282839 scopus 로고    scopus 로고
    • Construction of a novel set of transfer vectors to study vaccinia virus replication and foreign gene expression
    • Dvoracek, B., and T. Shors. 2003. Construction of a novel set of transfer vectors to study vaccinia virus replication and foreign gene expression. Plasmid 49: 9-17.
    • (2003) Plasmid , vol.49 , pp. 9-17
    • Dvoracek, B.1    Shors, T.2
  • 17
    • 0016435261 scopus 로고
    • Generalized contagious ecthyma in a sheep rancher: Diagnostic considerations
    • Erickson, G. A., E. A. Carbrey, and G. A. Gustafson. 1975. Generalized contagious ecthyma in a sheep rancher: diagnostic considerations. J. Am. Vet. Med. Assoc. 166: 262-263.
    • (1975) J. Am. Vet. Med. Assoc. , vol.166 , pp. 262-263
    • Erickson, G.A.1    Carbrey, E.A.2    Gustafson, G.A.3
  • 18
    • 0033788433 scopus 로고    scopus 로고
    • Evidence for a parapox ovis virus-associated superantigen
    • Fachinger, V., T. Schlapp, and A. Saalmuller. 2000. Evidence for a parapox ovis virus-associated superantigen. Eur. J. Immunol. 30: 2962-2971.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2962-2971
    • Fachinger, V.1    Schlapp, T.2    Saalmuller, A.3
  • 19
    • 0033887425 scopus 로고    scopus 로고
    • Poxvirus-induced immunostimulating effects on porcine leukocytes
    • Fachinger, V., T. Schlapp, W. Strube, N. Schmeer, and A. Saalmuller. 2000. Poxvirus-induced immunostimulating effects on porcine leukocytes. J. Virol. 74: 7943-7951.
    • (2000) J. Virol. , vol.74 , pp. 7943-7951
    • Fachinger, V.1    Schlapp, T.2    Strube, W.3    Schmeer, N.4    Saalmuller, A.5
  • 20
    • 0033834737 scopus 로고    scopus 로고
    • Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus orf virus
    • Fleming, S. B., D. M. Haig, P. Nettleton, H. W. Reid, C. A. McCaughan, L. M. Wise, and A. Mercer. 2000. Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus orf virus. Virus Genes 21: 85-95.
    • (2000) Virus Genes , vol.21 , pp. 85-95
    • Fleming, S.B.1    Haig, D.M.2    Nettleton, P.3    Reid, H.W.4    McCaughan, C.A.5    Wise, L.M.6    Mercer, A.7
  • 21
    • 49449100978 scopus 로고    scopus 로고
    • Genus parapoxvirus
    • A. A. Mercer, A. Schmidt, and O. Weber ed., Birkhäuser, Basel, Switzerland
    • Fleming, S. B., and A. A. Mercer. 2007. Genus Parapoxvirus, p. 127-165. In A. A. Mercer, A. Schmidt, and O. Weber (ed.), Poxviruses. Birkhäuser, Basel, Switzerland.
    • (2007) Poxviruses , pp. 127-165
    • Fleming, S.B.1    Mercer, A.A.2
  • 22
    • 4143116738 scopus 로고    scopus 로고
    • Immunomodulatory effects of inactivated parapoxvirus ovis (ORF virus) on human peripheral immune cells: Induction of cytokine secretion in monocytes and Th1-like cells
    • Friebe, A., A. Siegling, S. Friederichs, H. D. Volk, and O. Weber. 2004. Immunomodulatory effects of inactivated parapoxvirus ovis (ORF virus) on human peripheral immune cells: induction of cytokine secretion in monocytes and Th1-like cells. J. Virol. 78: 9400-9411.
    • (2004) J. Virol. , vol.78 , pp. 9400-9411
    • Friebe, A.1    Siegling, A.2    Friederichs, S.3    Volk, H.D.4    Weber, O.5
  • 23
    • 1342288026 scopus 로고    scopus 로고
    • Affy-analysis of Affymetrix GeneChip data at the probe level
    • Gautier, L., L. Cope, B. M. Bolstad, and R. A. Irizarry. 2004. Affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20: 307-315.
    • (2004) Bioinformatics , vol.20 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 24
    • 33748661699 scopus 로고    scopus 로고
    • Poxviral regulation of the host NF-κB response: The vaccinia virus M2L protein inhibits induction of NF-κB activation via an ERK2 pathway in virus-infected human embryonic kidney cells
    • Gedey, R., X. L. Jin, O. Hinthong, and J. L. Shisler. 2006. Poxviral regulation of the host NF-κB response: the vaccinia virus M2L protein inhibits induction of NF-κB activation via an ERK2 pathway in virus-infected human embryonic kidney cells. J. Virol. 80: 8676-8685.
    • (2006) J. Virol. , vol.80 , pp. 8676-8685
    • Gedey, R.1    Jin, X.L.2    Hinthong, O.3    Shisler, J.L.4
  • 27
    • 0038356874 scopus 로고    scopus 로고
    • Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis
    • Guo, J., Z. Zhang, J. F. Edwards, R. W. Ermel, C. Taylor, Jr., and A. de la Concha-Bermejillo. 2003. Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis. Virus Res. 93: 169-179.
    • (2003) Virus Res. , vol.93 , pp. 169-179
    • Guo, J.1    Zhang, Z.2    Edwards, J.F.3    Ermel, R.W.4    Taylor Jr., C.5    De La Concha-Bermejillo, A.6
  • 28
    • 0036711438 scopus 로고    scopus 로고
    • Immunity and counter-immunity during infection with the parapoxvirus orf virus
    • Haig, D. M., and C. J. McInnes. 2002. Immunity and counter-immunity during infection with the parapoxvirus orf virus. Virus Res. 88: 3-16.
    • (2002) Virus Res. , vol.88 , pp. 3-16
    • Haig, D.M.1    McInnes, C.J.2
  • 31
    • 33750433585 scopus 로고    scopus 로고
    • Manipulation of the nuclear factor-κB pathway and the innate immune response by viruses
    • Hiscott, J., T. L. Nguyen, M. Arguello, P. Nakhaei, and S. Paz. 2006. Manipulation of the nuclear factor-κB pathway and the innate immune response by viruses. Oncogene 25: 6844-6867.
    • (2006) Oncogene , vol.25 , pp. 6844-6867
    • Hiscott, J.1    Nguyen, T.L.2    Arguello, M.3    Nakhaei, P.4    Paz, S.5
  • 33
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin, M., and Y. Ben-Neriah. 2000. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18: 621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 34
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-κB by Toll-like receptors
    • Kawai, T., and S. Akira. 2007. Signaling to NF-κB by Toll-like receptors. Trends Mol. Med. 13: 460-469.
    • (2007) Trends Mol. Med. , vol.13 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 36
    • 17844386319 scopus 로고    scopus 로고
    • IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
    • Lawrence, T., M. Bebien, G. Y. Liu, V. Nizet, and M. Karin. 2005. IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation. Nature 434: 1138-1143.
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 37
    • 33947114420 scopus 로고    scopus 로고
    • Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13
    • Matta, H., R. M. Surabhi, J. Zhao, V. Punj, Q. Sun, S. Schamus, L. Mazzacurati, and P. M. Chaudhary. 2007. Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13. Oncogene 26: 1656-1660.
    • (2007) Oncogene , vol.26 , pp. 1656-1660
    • Matta, H.1    Surabhi, R.M.2    Zhao, J.3    Punj, V.4    Sun, Q.5    Schamus, S.6    Mazzacurati, L.7    Chaudhary, P.M.8
  • 38
    • 84995171775 scopus 로고
    • Experimental detection of the paraspecific effects of purified and inactivated poxviruses
    • Mayr, A., M. Buttner, G. Wolf, H. Meyer, and C. Czerny. 1989. Experimental detection of the paraspecific effects of purified and inactivated poxviruses. Zentralbl. Veterinarmed. B 36: 81-99.
    • (1989) Zentralbl. Veterinarmed. B , vol.36 , pp. 81-99
    • Mayr, A.1    Buttner, M.2    Wolf, G.3    Meyer, H.4    Czerny, C.5
  • 39
    • 0024969170 scopus 로고
    • Detection of contagious pustular dermatitis virus of goats in a severe outbreak
    • Mazur, C., and R. D. Machado. 1989. Detection of contagious pustular dermatitis virus of goats in a severe outbreak. Vet. Rec. 125: 419-420.
    • (1989) Vet. Rec. , vol.125 , pp. 419-420
    • Mazur, C.1    Machado, R.D.2
  • 41
    • 70349918182 scopus 로고    scopus 로고
    • NFκB inhibitors: Strategies from poxviruses
    • Mohamed, M. R., and G. McFadden. 2009. NFκB inhibitors: strategies from poxviruses. Cell Cycle 8: 3125-3132.
    • (2009) Cell. Cycle , vol.8 , pp. 3125-3132
    • Mohamed, M.R.1    McFadden, G.2
  • 42
    • 69449103056 scopus 로고    scopus 로고
    • Cowpox virus expresses a novel ankyrin repeat NF-κB inhibitor that controls inflammatory cell influx into virus-infected tissues and is critical for virus pathogenesis
    • Mohamed, M. R., M. M. Rahman, A. Rice, R. W. Moyer, S. J. Werden, and G. McFadden. 2009. Cowpox virus expresses a novel ankyrin repeat NF-κB inhibitor that controls inflammatory cell influx into virus-infected tissues and is critical for virus pathogenesis. J. Virol. 83: 9223-9236.
    • (2009) J. Virol. , vol.83 , pp. 9223-9236
    • Mohamed, M.R.1    Rahman, M.M.2    Rice, A.3    Moyer, R.W.4    Werden, S.J.5    McFadden, G.6
  • 43
    • 42449154473 scopus 로고    scopus 로고
    • Poxviruses: The viruses and their replication
    • D. M. Knipe and P. M. Howley ed., Wolters Kluwer Health/Lippincott/The Williams & Wilkins Co., Philadelphia, PA
    • Moss, B. 2007. Poxviruses: the viruses and their replication, p. 2905-2946. In D. M. Knipe and P. M. Howley (ed.), Fields virology, vol. 2. Wolters Kluwer Health/Lippincott/The Williams & Wilkins Co., Philadelphia, PA.
    • (2007) Fields Virology , vol.2 , pp. 2905-2946
    • Moss, B.1
  • 45
    • 24944450688 scopus 로고    scopus 로고
    • The MCV MC159 protein inhibits late, but not early, events of TNF-alpha-induced NF-κB activation
    • Murao, L. E., and J. L. Shisler. 2005. The MCV MC159 protein inhibits late, but not early, events of TNF-alpha-induced NF-κB activation. Virology 340: 255-264.
    • (2005) Virology , vol.340 , pp. 255-264
    • Murao, L.E.1    Shisler, J.L.2
  • 46
    • 67449107496 scopus 로고    scopus 로고
    • Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-κB, and IRF3 pathways
    • Myskiw, C., J. Arsenio, R. van Bruggen, Y. Deschambault, and J. Cao. 2009. Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-κB, and IRF3 pathways. J. Virol. 83: 6757-6768.
    • (2009) J. Virol. , vol.83 , pp. 6757-6768
    • Myskiw, C.1    Arsenio, J.2    Van Bruggen, R.3    Deschambault, Y.4    Cao, J.5
  • 47
    • 33847229036 scopus 로고    scopus 로고
    • Roles of NF-κB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA
    • Nakamichi, K., M. Saiki, H. Kitani, Y. Kuboyama, K. Morimoto, M. Takayama-Ito, and I. Kurane. 2007. Roles of NF-κB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA. Neurosci. Lett. 414: 222-227.
    • (2007) Neurosci. Lett , vol.414 , pp. 222-227
    • Nakamichi, K.1    Saiki, M.2    Kitani, H.3    Kuboyama, Y.4    Morimoto, K.5    Takayama-Ito, M.6    Kurane, I.7
  • 48
  • 49
    • 0030581530 scopus 로고    scopus 로고
    • Natural transmission of orf virus from clinically normal ewes to orf-naive sheep
    • Nettleton, P. F., J. A. Gilray, D. L. Yirrell, G. R. Scott, and H. W. Reid. 1996. Natural transmission of orf virus from clinically normal ewes to orf-naive sheep. Vet. Rec. 139: 364-366.
    • (1996) Vet. Rec. , vol.139 , pp. 364-366
    • Nettleton, P.F.1    Gilray, J.A.2    Yirrell, D.L.3    Scott, G.R.4    Reid, H.W.5
  • 50
    • 63149089887 scopus 로고    scopus 로고
    • Poxvirus MC160 protein utilizes multiple mechanisms to inhibit NF-κB activation mediated via components of the tumor necrosis factor receptor 1 signal transduction pathway
    • Nichols, D. B., and J. L. Shisler. 2009. Poxvirus MC160 protein utilizes multiple mechanisms to inhibit NF-κB activation mediated via components of the tumor necrosis factor receptor 1 signal transduction pathway. J. Virol. 83: 3162-3174.
    • (2009) J. Virol. , vol.83 , pp. 3162-3174
    • Nichols, D.B.1    Shisler, J.L.2
  • 51
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-κB transcription factors
    • Pahl, H. L. 1999. Activators and target genes of Rel/NF-κB transcription factors. Oncogene 18: 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 52
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-κB and IKK function
    • Perkins, N. D. 2007. Integrating cell-signalling pathways with NF-κB and IKK function. Nat. Rev. Mol. Cell. Biol. 8: 49-62.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 53
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor κB pathway
    • Perkins, N. D. 2006. Post-translational modifications regulating the activity and function of the nuclear factor κB pathway. Oncogene 25: 6717-6730.
    • (2006) Oncogene , vol.25 , pp. 6717-6730
    • Perkins, N.D.1
  • 54
    • 0032589462 scopus 로고    scopus 로고
    • IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
    • Sakurai, H., H. Chiba, H. Miyoshi, T. Sugita, and W. Toriumi. 1999. IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 274: 30353-30356.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 55
    • 0021929664 scopus 로고
    • Orf. A case report with histologic, electron microscopic, and immunoperoxidase studies
    • Sanchez, R. L., A. Hebert, H. Lucia, and J. Swedo. 1985. Orf. A case report with histologic, electron microscopic, and immunoperoxidase studies. Arch. Pathol. Lab. Med. 109: 166-170.
    • (1985) Arch. Pathol. Lab. Med. , vol.109 , pp. 166-170
    • Sanchez, R.L.1    Hebert, A.2    Lucia, H.3    Swedo, J.4
  • 56
    • 0038605236 scopus 로고    scopus 로고
    • NF-κB and virus infection: Who controls whom
    • Santoro, M. G., A. Rossi, and C. Amici. 2003. NF-κB and virus infection: who controls whom. EMBO J. 22: 2552-2560.
    • (2003) EMBO J. , vol.22 , pp. 2552-2560
    • Santoro, M.G.1    Rossi, A.2    Amici, C.3
  • 57
    • 33750443289 scopus 로고    scopus 로고
    • IκB kinase complexes: Gateways to NF-κB activation and transcription
    • Scheidereit, C. 2006. IκB kinase complexes: gateways to NF-κB activation and transcription. Oncogene 25: 6685-6705.
    • (2006) Oncogene , vol.25 , pp. 6685-6705
    • Scheidereit, C.1
  • 59
    • 1842614361 scopus 로고    scopus 로고
    • The vaccinia virus K1L gene product inhibits host NF-κB activation by preventing IκBα degradation
    • Shisler, J. L., and X. L. Jin. 2004. The vaccinia virus K1L gene product inhibits host NF-κB activation by preventing IκBα degradation. J. Virol. 78: 3553-3560.
    • (2004) J. Virol. , vol.78 , pp. 3553-3560
    • Shisler, J.L.1    Jin, X.L.2
  • 61
    • 56349171612 scopus 로고    scopus 로고
    • Genus Orthopoxvirus: Vaccinia virus
    • A. A. Mercer, A. Schmidt, and O. Weber ed., Birkhäuser, Basel, Switzerland
    • Smith, G. L. 2007. Genus Orthopoxvirus: vaccinia virus, p. 1-45. In A. A. Mercer, A. Schmidt, and O. Weber (ed.), Poxviruses. Birkhäuser, Basel, Switzerland.
    • (2007) Poxviruses , pp. 1-45
    • Smith, G.L.1
  • 63
    • 37849012459 scopus 로고    scopus 로고
    • The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities
    • Unterholzner, L., and A. G. Bowie. 2008. The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities. Biochem. Pharmacol. 75: 589-602.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 589-602
    • Unterholzner, L.1    Bowie, A.G.2
  • 64
    • 77950623779 scopus 로고    scopus 로고
    • Immunomodulation by inactivated Orf virus (ORFV) : Therapeutic potential
    • A. A. Mercer, A. Schmidt, and O. Weber ed., Birkhäuser, Basel, Switzerland
    • Weber, O., P. Knolle, and H. D. Volk. 2007. Immunomodulation by inactivated Orf virus (ORFV) : therapeutic potential, p. 297-310. In A. A. Mercer, A. Schmidt, and O. Weber (ed.), Poxviruses. Birkhäuser, Basel, Switzerland.
    • (2007) Poxviruses , pp. 297-310
    • Weber, O.1    Knolle, P.2    Volk, H.D.3
  • 65
    • 44749093460 scopus 로고    scopus 로고
    • Ubiquitin-mediated regulation of TNFR1 signaling
    • Wertz, I. E., and V. M. Dixit. 2008. Ubiquitin-mediated regulation of TNFR1 signaling. Cytokine Growth Factor Rev. 19: 313-324.
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 313-324
    • Wertz, I.E.1    Dixit, V.M.2
  • 66
  • 67
    • 24944534978 scopus 로고    scopus 로고
    • Real-time PCR for mRNA quantitation
    • Wong, M. L., and J. F. Medrano. 2005. Real-time PCR for mRNA quantitation. Biotechniques 39: 75-85.
    • (2005) Biotechniques , vol.39 , pp. 75-85
    • Wong, M.L.1    Medrano, J.F.2
  • 68
    • 23844551199 scopus 로고    scopus 로고
    • Stochastic models inspired by hybridization theory for short oligonucleotide arrays
    • Wu, Z., and R. A. Irizarry. 2005. Stochastic models inspired by hybridization theory for short oligonucleotide arrays. J. Comput. Biol. 12: 882-893.
    • (2005) J. Comput. Biol. , vol.12 , pp. 882-893
    • Wu, Z.1    Irizarry, R.A.2
  • 69
  • 70
    • 0031261719 scopus 로고    scopus 로고
    • The use of Baypamun N in crowding associated infectious respiratory disease: Efficacy of Baypamun N (freeze-dried product) in 4-10 month old horses
    • Ziebell, K. L., H. Steinmann, D. Kretzdorn, T. Schlapp, K. Failing, and N. Schmeer. 1997. The use of Baypamun N in crowding associated infectious respiratory disease: efficacy of Baypamun N (freeze-dried product) in 4-10 month old horses. Zentralbl. Veterinarmed. B 44: 529-536.
    • (1997) Zentralbl. Veterinarmed. B , vol.44 , pp. 529-536
    • Ziebell, K.L.1    Steinmann, H.2    Kretzdorn, D.3    Schlapp, T.4    Failing, K.5    Schmeer, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.