A role for novel cell-cycle proteins in podocyte biology

Kidney International

Volumn 77, Issue 8, 2010, Pages 660-661

  Price, Peter M ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE 5; MESSENGER RNA; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL REGENERATION; CELL SURVIVAL; CELL TYPE; CHRONIC KIDNEY DISEASE; EMBRYO DEVELOPMENT; KIDNEY; KIDNEY TUBULE; MOUSE; NONHUMAN; NOTE; PODOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRESS; ULTRAVIOLET IRRADIATION;

EID: 77950505811     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2009.562     Document Type: Note

References (13)

1. Price PM, Safirstein RL, Megyesi J. The cell cycle and acute kidney injury. Kidney Int 2009; 76: 604-613.
2. Griffin SV, Hiromura K, Pippin J et al. Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology. Am J Pathol 2004; 165: 1175-1185.
3. Brinkkoetter PT, Wu JS, Ohse T et al. p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo. Kidney Int 2010; 77: 690-699.
4. Griffin SV, Olivier JP, Pippin JW et al. Cyclin I protects podocytes from apoptosis. J Biol Chem 2006; 281: 28048-28057.
5. Dhavan R, Tsai L-H. A decade of Cdk5. Nat Rev Mol Cell Biol 2001; 2: 749-759.
6. Ohshima T, Ward JM, Huh CG et al. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci USA 1996; 93: 11173-11178.
7. Ko J, Humbert S, Bronson RT et al. p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci 2001; 21: 6758-6771.
8. Li B-S, Zhang L, Takahashi S et al. Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3. EMBO J 2002; 21: 324-333.
9. Patrick GN, Zukerberg L, Nikolic M et al. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 1999; 402: 615-622.
10. Brinkkoetter PT, Olivier P, Wu JS et al. Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells. J Clin Invest 2009; 119: 3089-3101.
11. Meuer K, Suppanz IE, Lingor P et al. Cyclindependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis. Cell Death Differ 2007; 14: 651-661. 12.
12. Satyanarayana A, Kaldis P. Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 28: 2925-2939.
13. Geng Y, Lee Y-M, Welcker M et al. Kinase-independent function of cyclin E. Mol Cell 2007; 25: 127-139.