Dynamics of extracellular release of Aspergillus fumigatus DNA and galactomannan during growth in blood and serum

Journal of Medical Microbiology

Volumn 59, Issue 4, 2010, Pages 408-413

  Morton, C O ^a   Loeffler, J ^b   De Luca, A ^c   Frost, S ^a   Kenny, C ^a   Duval, S ^a   Romani, L ^c   Rogers, T R ^a  

^a ST JAMES S HOSPITAL   (Ireland)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; GALACTOMANNAN; MANNAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; BLOOD; BLOOD SAMPLING; CONIDIUM; CONTROLLED STUDY; DISEASE MODEL; DNA DETERMINATION; FUNGAL BIOMASS; FUNGUS GROWTH; HUMAN; IN VITRO STUDY; INOCULATION; MOLECULAR DYNAMICS; NONHUMAN; PLASMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ANIMAL; C57BL MOUSE; CULTURE MEDIUM; GENETICS; GROWTH, DEVELOPMENT AND AGING; MOUSE; SECRETION;

ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CULTURE MEDIA; DNA, FUNGAL; HUMANS; MANNANS; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION;

EID: 77950487354     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.017418-0     Document Type: Article

References (23)

1. Alexander, B. D. (2002). Diagnosis of fungal infection: new technologies for the mycology laboratory. Transpl Infect Dis 4 (Suppl. 3), 32-37.
2. Botterel, F., Farrugia, C., Ichai, P., Costa, J.M., Saliba, F. & Bretagne, S. (2008). Real-time PCR on the first galactomannan-positive serum sample for diagnosing invasive aspergillosis in liver transplant recipients. Transpl Infect Dis 10, 333-338.
3. Bowman, J. C., Abruzzo, G. K., Anderson, J. W., Flattery, A. M., Gill, C. J., Pikounis, V. B., Schmatz, D. M., Liberator, P. A. & Douglas, C. M. (2001). Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate. Antimicrob Agents Chemother 45, 3474-3481.
4. Cuenca-Estrella, M., Meije, Y., Diaz-Pedroche, C., Gomez-Lopez, A., Buitrago, M. J., Bernal-Martinez, L., Grande, C., Juan, R. S., Lizasoain, M. & other authors (2009). Value of serial quantification of fungal DNA by a real-time PCR-based technique for early diagnosis of invasive aspergillosis in patients with febrile neutropenia. J Clin Microbiol 47, 379-384.
5. de Pauw, B., Walsh, T. J., Donnelly, J. P., Stevens, D. A., Edwards, J. E., Calandra, T., Pappas, P. G., Maertens, J., Lortholary, O. & other authors (2008). Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 46, 1813-1821.
6. Gifford, A. H., Klippenstein, J. R. & Moore, M. M. (2002). Serum stimulates growth of and proteinase secretion by Aspergillus fumigatus. Infect Immun 70, 19-26.
7. Izano, E. A., Amarante, M. A., Kher, W. B. & Kaplan, J. B. (2008). Differential roles of poly-N-acetylglucosamine surface polysaccharide and extracellular DNA in Staphylococcus aureus and Staphylococcus epidermidis biofilms. Appl Environ Microbiol 74, 470-476.
8. Kasai, M., Francesconi, A., Petraitiene, R., Petraitis, V., Kelaher, A. M., Kim, H. S., Meletiadis, J., Sein, T., Bacher, J. & Walsh, T. J. (2006). Use of quantitative real-time PCR to study the kinetics of extracellular DNA released from Candida albicans, with implications for diagnosis of invasive candidiasis. J Clin Microbiol 44, 143-150. (Pubitemid 43100593)
9. Lin, J. S., Yang, C. W., Wang, D. W. & Wu-Hsieh, B. A. (2005). Dendritic cells cross-present exogenous fungal antigens to stimulate a protective CD8 T cell response in infection by Histoplasma capsulatum. J Immunol 174, 6282-6291.
10. Mengoli, C., Cruciani, M., Barnes, R. A., Loeffler, J. & Donnelly, J. P. (2009). Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis. Lancet Infect Dis 9, 89-96.
11. Mennink-Kersten, M. A., Ruegebrink, D., Wasei, N., Melchers, W. J. & Verweij, P. E. (2006). In vitro release by Aspergillus fumigatus of galactofuranose antigens, 1,3-beta-D-glucan, and DNA, surrogate markers used for diagnosis of invasive aspergillosis. J Clin Microbiol 44, 1711-1718.
12. Miyazato, A., Nakamura, K., Yamamoto, N., Mora-Montes, H. M., Tanaka, M., Abe, Y., Tanno, D., Inden, K., Gang, X. & other authors (2009). Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans. Infect Immun 77, 3056-3064.
13. Mousavi, S. A. & Robson, G. D. (2003). Entry into the stationary phase is associated with a rapid loss of viability and an apoptotic-like phenotype in the opportunistic pathogen Aspergillus fumigatus. Fungal Genet Biol 39, 221-229.
14. Mowat, E., Williams, C., Jones, B., McChlery, S. & Ramage, G. (2009). The characteristics of Aspergillus fumigatus mycetoma development: is this a biofilm? Med Mycol 47 (Suppl. 1), S120-S126.
15. Neofytos, D., Horn, D., Anaissie, E., Steinbach, W., Olyaei, A., Fishman, J., Pfaller, M., Chang, C., Webster, K. & Marr, K. (2009). Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry. Clin Infect Dis 48, 265-273.
16. Perlin, D. S. & Zhao, Y. (2009). Molecular diagnostic platforms for detecting Aspergillus. Med Mycol 47 (Suppl. 1), S223-S232.
17. Romani, L., Fallarino, F., De Luca, A., Montagnoli, C., D'Angelo, C., Zelante, T., Vacca, C., Bistoni, F., Fioretti, M. C. & other authors (2008). Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature 451, 211-215.
18. Schmidt, B., Weickmann, S., Witt, C. & Fleischhacker, M. (2005). Improved method for isolating cell-free DNA. Clin Chem 51, 1561-1563. (Pubitemid 41060908)
19. Stephens-Romero, S. D., Mednick, A. J. & Feldmesser, M. (2005). The pathogenesis of fatal outcome in murine pulmonary aspergillosis depends on the neutrophil depletion strategy. Infect Immun 73, 114-125.
20. Suarez, F., Lortholary, O., Buland, S., Rubio, M. T., Ghez, D., Mahé, V., Quesne, G., Poirée, S., Buzyn, A. & other authors (2008). Detection of circulating Aspergillus fumigatus DNA by real-time PCR assay of large serum volumes improves early diagnosis of invasive aspergillosis in high-risk adult patients under hematologic surveillance. J Clin Microbiol 46, 3772-3777.
21. White, P. L. & Barnes, R. A. (2009). Aspergillus PCR. In Aspergillus fumigatus and Aspergillosis, pp. 373-388. Edited by J. Latge & W. Steinbach. Washington, DC: American Society for Microbiology.
22. White, P. L., Perry, M. D. & Barnes, R. A. (2009). An update on the molecular diagnosis of invasive fungal disease. FEMS Microbiol Lett 296, 1-10.
23. Zarember, K. A., Sugui, J. A., Chang, Y. C., Kwon-Chung, K. J. & Gallin, J. I. (2007). Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion. J Immunol 178, 6367-6373.