MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway

International Journal of Oncology

Volumn 36, Issue 5, 2010, Pages 1209-1215

  Ortega, Paloma ^a   Moran, Alberto ^a   Fernandez Marcelo, Tamara ^a   De Juan, Carmen ^a   Frias, Cristina ^a   Lopez Asenjo, José Antonio ^b   Sanchez Pernaute, Andrés ^b   Torres, Antonio ^b   Diaz Rubio, Eduardo ^b   Iniesta, Pilar ^a   Benito, Manuel ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Adhesion; Colorectal cancer; Metalloproteinases; MMP 7; Mutator phenotype pathway; SGCE

Indexed keywords

MATRILYSIN;

ARTICLE; CANCER INVASION; COLORECTAL CANCER; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MUTATOR GENE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SGCE GENE;

CELL ADHESION MOLECULES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 7; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MUTATION; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SARCOGLYCANS;

EID: 77950455567     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000604     Document Type: Article

References (30)

1. Fearon ER and Vogelstein B: A genetic model for colorectal tumourigenesis. Cell 61: 759-767, 1990.
2. Cunningham JM, Christensen ER, Tester DJ, Kim CY, Roche PC, Burgart LJ and Thibodeau SN: Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res 58: 3455-3460, 1998.
3. Koopman M, Kortman GA, Mekenkamp L, Ligtenberg MJ, Hoogerbrugge N, Antonini NF, Punt CJ and van Krieken JH: Deficient mismatch repair system in patients with sporadic advanced colorectal cancer. Br J Cancer 100: 266-273, 2009.
4. Jass JR, Walsh MD, Barker M, Simms LA, Young J and Leggett BA: Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability. Eur J Cancer 38: 858-866, 2002.
5. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN and Srivastava S: National Cancer Institute Workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257, 1998.
6. Benatti P, Gafà R, Barana D, Marino M, Scarselli A, Pedroni M, Maestri I, Guerzoni L, Roncucci L, Menigatti M, Roncari B, Maffei S, Rossi G, Ponti G, Santini A, Losi L, Di Gregorio C, Oliani C, Ponz de Leon M and Lanza G: Microsatellite instability and colorectal cancer prognosis. Clin Cancer Res 11: 8332-8340, 2005.
7. Munshi HG and Stack MS: Reciprocal interactions between adhesion receptor signaling and MMP regulation. Cancer Metastasis Rev 25: 45-56, 2006.
8. Gutiérrez-Fernández A, Fueyo A, Folgueras AR, Garabaya C, Pennington CJ, Pilgrim S, Edwards DR, Holliday DL, Jones JL, Span PN, Sweep FC, Puente XS and López-Otín C: Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumour cell adhesion and invasion. Cancer Res 68: 2755-2763, 2008.
9. Nagase H, Visse R and Murphy G: Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69: 562-573, 2006.
10. Lochter A, Galosy S, Muschler J, Freedman N, Werb Z and Bissell MJ: Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to- mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol 139: 1861-1872, 1997.
11. Iyer V, Pumiglia K and DiPersio CM: Alpha3beta1 integrin regulates MMP-9 mRNA stability in immortalized keratino-cytes: a novel mechanism of integrin-mediated MMP gene expression. J Cell Sci 118: 1185-1195, 2005.
12. Baronas-Lowell D, Lauer-Fields JL, Borgia JA, Sferrazza GF, Al-Ghoul M, Minond D and Fields GB: Differential modulation of human melanoma cell metalloproteinase expression by alpha2beta1 integrin and CD44 triple-helical ligands derived from type IV collagen. J Biol Chem 279: 43503-43513, 2004.
13. Ortega P, Morán A, de Juan C, Frías C, Hernández S, López- Asenjo JA, Sánchez-Pernaute A, Torres A, Iniesta P and Benito M: Differential Wnt pathway gene expression and E-cadherin truncation in sporadic colorectal cancers with and without micro-satellite instability. Clin Cancer Res 14: 995-1001, 2008.
14. Morán A, Iniesta P, de Juan C, García-Aranda C, Díaz-López A and Benito M: Impairment of stromelysin-1 transcriptional activity by promoter mutations in high microsatellite instability colorectal tumours. Cancer Res 65: 3811-3814, 2005.
15. Morán A, Iniesta P, de Juan C, González-Quevedo R, Sánchez- Pernaute A, Díaz-Rubio E, Ramón y Cajal S, Torres A, Balibrea JL and Benito M: Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumours. Cancer Res 62: 3855-3860, 2002.
16. Blin N and Stafford DW: A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 3: 2303-2308, 1976.
17. Giles RH, van Es JH and Clevers H: Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 1653: 1-24, 2003.
18. Rubinfeld B, Souza B, Albert I, Munemitsu S and Polakis P: The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin. J Biol Chem 270: 5549-5555, 1995.
19. Orsulic S, Huber O, Aberle H, Arnold S and Kemler R: E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/ LEF-1-mediated transactivation. J Cell Sci 112: 1237-1245, 1999.
20. Gottardi CJ, Wong E and Gumbiner BM: E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner. J Cell Biol 153: 1049-1460, 2001.
21. Brabletz T, Jung A, Dag S, Hlubek F and Kirchner T: Beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol 155: 1033-1038, 1999.
22. Takahashi M, Tsunoda T, Seiki M, Nakamura Y and Furukawa Y: Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Oncogene 21: 5861-5867, 2002.
23. Marchenko ND, Marchenko GN, Weinreb RN, Lindsey JD, Kyshtoobayeva A, Crawford HC and Strongin AY: Beta-catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells. Int J Biochem Cell Biol 36: 942-956, 2004.
24. Wu B, Crampton SP and Hughes CC: Wnt signaling induces matrix metalloproteinase expression and regulates T cell trans-migration. Immunity 26: 227-239, 2007.
25. Fang YJ, Lu ZH, Wang GQ, Pan ZZ, Zhou ZW, Yun JP, Zhang MF and Wan DS: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. Int J Colorectal Dis 24: 875-884, 2009.
26. Luo HZ, Zhou ZG, Yang L, Yu YY, Tian C, Zhou B, Zheng XL, Xia QJ, Li Y and Wang R: Clinicopathologic and prognostic significance of MMP-7 (matrilysin) expression in human rectal cancer. Jpn J Clin Oncol 35: 739-744, 2005.
27. Ougolkov AV, Yamashita K, Mai M and Minamoto T: Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer. Gastroenterology 122: 60-71, 2002.
28. Nardocci N, Zorzi G, Barzaghi C, Zibordi F, Ciano C, Ghezzi D and Garavaglia B: Myoclonus-dystonia syndrome: clinical presentation, disease course, and genetic features in 11 families. Mov Disord 23: 28-34, 2008.
29. Dong H, Ge X, Shen Y, Chen L, Kong Y, Zhang H, Man X, Tang L, Yuan H, Wang H, Zhao G and Jin W: Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE. BMC Med Genomics 2: 5, 2009.
30. Kainz B, Shehata M, Bilban M , Kienle D, Heintel D, Krömer- Holzinger E, Le T, Kröber A, Heller G, Schwarzinger I, Demirtas D, Chott A, Döhner H, Zöchbauer-Müller S, Fonatsch C, Zielinski C, Stilgenbauer S, Gaiger A, Wagner O and Jäger U: Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia. Int J Cancer 121: 1984-1993, 2007.