Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 11, 2010, Pages 4884-4889

  Srivastava, Anand ^a   Gangnard, Stéphane ^a   Round, Adam ^b   Dechavanne, Sébastien ^a   Juillerat, Alexandre ^a   Raynal, Bertrand ^a   Faure, Grazyna ^a   Baron, Bruno ^a   Ramboarina, Stéphanie ^a   Singh, Saurabh Kumar ^b   Belrhali, Hassan ^b   England, Patrick ^a   Lewit Bentley, Anita ^a   Scherf, Artur ^a   Bentley, Graham A ^a   Gamaina, Benoît ^a  

^a CNRS   (France)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

Chondroitin; Malaria; Plasmodium; Pregnancy; Structure

Indexed keywords

CHONDROITIN 4 SULFATE; DUFFY BINDING PROTEIN; ERYTHROCYTE MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VAR2CSA PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NONHUMAN; PLASMODIUM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIGENS, PROTOZOAN; CELL LINE; CHONDROITIN SULFATES; CIRCULAR DICHROISM; ERYTHROCYTES; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SPACE; FEMALE; HUMANS; KINETICS; MODELS, MOLECULAR; PARASITES; PLACENTA; PLASMODIUM FALCIPARUM; PREGNANCY; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; RECOMBINANT PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 77950415354     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1000951107     Document Type: Article

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