Prolonged infusion of eptifibatide as bridge therapy between bare-metal stent insertion and cardiovascular surgery: Case report and review of the literature

Pharmacotherapy

Volumn 30, Issue 4, 2010, Pages

  Pickett, Andrea M ^a   Taylor, Dylan A ^a,b   Ackman, Margaret L ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

Coronary artery bypass grafting; Eptifibatide; Hemorrhage; Stent

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; ENOXAPARIN; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST;

ADULT; ANGIOPLASTY; ARTICLE; BARE METAL STENT; BLEEDING; CARDIOVASCULAR SURGERY; CASE REPORT; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY STENT; DRUG EFFICACY; DRUG INFUSION; DRUG SAFETY; DRUG WITHDRAWAL; ELECTROCARDIOGRAM; EMERGENCY WARD; HEART INFARCTION; HUMAN; LOADING DRUG DOSE; MALE; MONOTHERAPY; RISK ASSESSMENT; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STENT THROMBOSIS; THORAX PAIN; THROMBOSIS;

ANGIOPLASTY; ANTICOAGULANTS; ASPIRIN; CARDIOVASCULAR SURGICAL PROCEDURES; CORONARY ARTERY BYPASS; HEMORRHAGE; HUMANS; MALE; METALS; MIDDLE AGED; PEPTIDES; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; STENTS; THROMBOSIS; TICLOPIDINE;

EID: 77950392809     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.30.4.420     Document Type: Article

References (34)

1. King SB, Smith SC, Hirshfield JW, et al. 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention. J Am Coll Cardiol 2008;51:172-209.
2. Grines CL, Bonow RO, Casey DE, et al. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents. J Am Coll Cardiol 2007;49:734-739
3. Hall P, Nakamura S, Maiello L, et al. A randomized comparison of combined ticlopidine and aspirin therapy versus aspirin therapy alone after successful intravascular ultrasound-guided stent implantation. Circulation 1996;93:215-222
4. Antman EM, Hand M, Armstrong PA, et al. 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction. J Am Coll Cardiol 2008;51:210-247
5. Douketis JD, Berger PB, Dunn AS, et al. The perioperative management of antithrombotic therapy: American College of Chest Physicians evidence-based clinical practice guidelines, 8th ed. Chest 2008;133:299S-339.
6. Dyke CM, Jennings LK, Maier G, et al. Preoperative platelet inhibition with eptifibatide during coronary artery bypass grafting with cardiopulmonary bypass. J Cardiovasc Pharmacol Ther 2007;12:54-60.
7. Sharis PJ, Cannon CP, Loscalzo J. The antiplatelet effects of ticlopidine and clopidogrel. Ann Int Med 1998;129:394-405.
8. Quinn MJ, Fitzgerald DJ. Ticlopidine and clopidogrel. Circulation 1999;100:1667-1672
9. Purkayastha P, Athanasiou T, Malinovski V, et al. Does clopidogrel affect outcome after coronary artery bypass grafting? A meta-analysis. Heart 2006;92:531-532
10. Pickard AS, Becker RC, Schumock GT, Frye CB. Clopidogrel-associated bleeding and related complications in patients undergoing coronary artery bypass grafting. Pharmacotherapy 2008;28:376-392
11. The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502.
12. Fox KAA, Mehta SR, Peters R, et al. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non ST-elevation acute coronary syndrome: the clopidogrel in unstable angina to prevent recurrent ischemic events (CURE) trial. Circulation 2004;110:1202-1208
13. Schomig A, Nuemann FJ, Kastrati A, et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996;334:1084-1089
14. Urban P, Macaya C Rupprecht HJ, et al. Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS). Circulation 1998;98:2126-2132
15. Bertrand ME, Legrand V, Boland J, et al. Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting: the full anticoagulation versus aspirin and ticlopidine (FANTASTIC) study. Circulation 1998;98:1597-1603
16. Leon MB, Baim DS, Popma JJ, et al for the Stent Anticoagulation Restenosis Study Investigators. A clinical trial comparing three antithrombotic drug regimens after coronaryartery stenting. N Engl J Med 1998;339:1665-1671
17. Patrono C, Baigent C, Hirsh J, et al. Antiplatelet drugs. American College of Chest Physicians evidence-based clinical practice guidelines, 8th ed. Chest 2008;133:199S-233.
18. Cornelius MD. Safety of glycoprotein IIb-IIIa inhibitors: a heart surgeon's perspective. Am Heart J 1999;138:307-316
19. Kleiman NS. Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors. Am Heart J 1999;138:S263-75.
20. EPIC Investigators. Use of monoclonal antibody directed against the platelet glycoprotein IIb/IIa receptor in high-risk coronary angioplasty. N Engl J Med 1994;330:956-961
21. Boehrer JD, Kereiakes DJ, Vavetta FI, et al, for the EPIC Investigators. Effects of profound platelet inhibition with c7E3 before coronary angioplasty on complications of coronary bypass surgery. Am J Cardiol 1994;74:1166-1170
22. Gammie JS, Zenati M, Kormos RL, et al. Abciximab and excessive bleeding in patients undergoing emergency cardiac operations Ann Thorac Surg 1998;65:465-469
23. Bizzarri F, Scolletta S, Tucci E, et al. Perioperative use of tirofiban hydrochloride (Aggrastat) does not increase surgical bleeding after emergency or urgent coronary artery bypass grafting. J Thorac Cardiovasc Surg 2001;122:1181-1185
24. Marso SP, Bhatt DL, Roe MT, et al. Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting. Circulation 2000;102:2952-2958
25. Dyke CM, Bhatia D, Lorenz TJ, et al. Immediate coronary artery bypass surgery after platelet inhibition with eptifibatide: results from PURSUIT. Ann Thorac Surg 2000;70:866-872
26. The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. N Engl J Med 1998;338:1488-1497
27. Cheng CKF, Jackevicius CA, Seidelin P, Feindel C, Rouleau JL. Safety of glycoprotein IIb/IIIa inhibitors in urgent or emergency coronary artery bypass graft surgery. Can J Cardiol 2004;20:223-228
28. Genoni M, Zeller D, Bertel O, Maloigne M, Turina M. Tirofiban therapy does not increase the risk of hemorrhage after emergency coronary surgery. J Thorac Cardiovasc Surg 2001;122:630-632
29. Curran MP, Keating GM. Eptifibatide. Drugs 2005;65:2009-2035
30. Goa KL, Noble S. Eptifibatide. Drugs 1999;57:439-462
31. The IMPACT-II Investigators. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT II. Lancet 1997;349:1422-1428
32. The PURSUIT Trial Investigators. Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med 1998;13:436-443
33. O'Shea JC, Hafley GE, Greenburg S, et al for the ESPRIT Investigators. Platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention: the ESPRIT trial - a randomized controlled trial. JAMA 2001;285:2468-2473
34. Jaffe R, Halon DA, Carmeli J, Lewis BS. Prolonged intravenous infusion for prevention of coronary stent thrombosis. Int J Cardiol 2007;114:409-411