메뉴 건너뛰기




Volumn 138, Issue 4 II, 1999, Pages

Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN DERIVATIVE; LAMIFIBAN; N ACETYLCYSTEINYLASPARAGINYLPROLYLARGINYLGLYCYLASPARTYL(O METHYLTYROSYL)ARGINYLCYSTEINAMIDE CYCLIC 1,9 DISULFIDE; TIROFIBAN;

EID: 0032886556     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1053/hj.1999.v138.a100459     Document Type: Conference Paper
Times cited : (71)

References (67)
  • 1
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • EPIC Investigators
    • EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med 1994;330:956-61.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 2
    • 8044222756 scopus 로고    scopus 로고
    • Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization
    • Lincoff AM, Tcheng JE, Califf RM, et al. Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization. Am J Cardiol 1997;79:286-91.
    • (1997) Am J Cardiol , vol.79 , pp. 286-291
    • Lincoff, A.M.1    Tcheng, J.E.2    Califf, R.M.3
  • 3
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
    • EPILOG Investigators
    • EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 1997;336:1689-96.
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
  • 4
    • 0032508297 scopus 로고    scopus 로고
    • Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade
    • EPISTENT Investigators
    • EPISTENT Investigators. Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade. Lancet 1998;352:87-92.
    • (1998) Lancet , vol.352 , pp. 87-92
  • 5
    • 0024396878 scopus 로고
    • Bleeding time: A guide to its diagnostic and clinical utility
    • Burns ER, Lawrence C. Bleeding time: a guide to its diagnostic and clinical utility. Arch Pathol Lab Med 1989;113:1219-24.
    • (1989) Arch Pathol Lab Med , vol.113 , pp. 1219-1224
    • Burns, E.R.1    Lawrence, C.2
  • 6
    • 0027737994 scopus 로고
    • Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7E3 glycoprotein IIb/IIIa platelet antibody
    • Bernardi MM, Califf RM, Kleiman N, et al. Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7E3 glycoprotein IIb/IIIa platelet antibody. Am J Cardiol 1993;72:1121-5.
    • (1993) Am J Cardiol , vol.72 , pp. 1121-1125
    • Bernardi, M.M.1    Califf, R.M.2    Kleiman, N.3
  • 7
    • 78651139188 scopus 로고
    • The aggregation of blood platelets
    • Lond
    • Born GVR, Cross MJ. The aggregation of blood platelets. J Physiol (Lond) 1963;168:178-95.
    • (1963) J Physiol , vol.168 , pp. 178-195
    • Born, G.V.R.1    Cross, M.J.2
  • 8
    • 0025231774 scopus 로고
    • Extracellular-free Ca++ accounts for the sex difference in the aggregation of human platelets in citrated platelet-rich plasma
    • Bell DN, Spain S, Goldsmith HL. Extracellular-free Ca++ accounts for the sex difference in the aggregation of human platelets in citrated platelet-rich plasma. Thromb Res 1990;58:47-60.
    • (1990) Thromb Res , vol.58 , pp. 47-60
    • Bell, D.N.1    Spain, S.2    Goldsmith, H.L.3
  • 9
    • 0021028111 scopus 로고
    • Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes
    • Fujimura K, Phillips DR. Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes. J Biol Chem 1983;258:10247-52.
    • (1983) J Biol Chem , vol.258 , pp. 10247-10252
    • Fujimura, K.1    Phillips, D.R.2
  • 10
    • 0023915420 scopus 로고
    • The platelet membrane glycoprotein IIb-IIIa complex
    • Phillips DR, Charo IF, Parise LV, et al. The platelet membrane glycoprotein IIb-IIIa complex. Blood 1988;71:831-43.
    • (1988) Blood , vol.71 , pp. 831-843
    • Phillips, D.R.1    Charo, I.F.2    Parise, L.V.3
  • 11
    • 0018866938 scopus 로고
    • Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation
    • Marguerie GA, Edgington TS, Plow EF. Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation. J Biol Chem 1980;255:154-61.
    • (1980) J Biol Chem , vol.255 , pp. 154-161
    • Marguerie, G.A.1    Edgington, T.S.2    Plow, E.F.3
  • 12
    • 0029664968 scopus 로고    scopus 로고
    • 3-integrins that regulates the dissociation rate for RGD ligands
    • 3-integrins that regulates the dissociation rate for RGD ligands. J Biol Chem 1996;271:21745-51.
    • (1996) J Biol Chem , vol.271 , pp. 21745-21751
    • Hu, D.D.1    Barbas, C.F.2    Smith, J.W.3
  • 14
    • 0028077510 scopus 로고
    • 3 subunit: Cation displacement is involved in ligand binding
    • 3 subunit: cation displacement is involved in ligand binding. Cell 1994;79:659-67.
    • (1994) Cell , vol.79 , pp. 659-667
    • D'Souza, S.E.1    Haas, T.A.2    Piotrowicz, R.S.3
  • 15
    • 0027972667 scopus 로고
    • Antithrombotic effects and bleeding time prolongation with synthetic platelet GP IIb/IIIa inhibitors in animal models of platelet-mediated thrombosis
    • Collen D, Lu HR, Stassen JM, et al. Antithrombotic effects and bleeding time prolongation with synthetic platelet GP IIb/IIIa inhibitors in animal models of platelet-mediated thrombosis. Thromb Haemost 1994;71:95-102.
    • (1994) Thromb Haemost , vol.71 , pp. 95-102
    • Collen, D.1    Lu, H.R.2    Stassen, J.M.3
  • 16
    • 0030610564 scopus 로고    scopus 로고
    • Effect of Ca2+ on GP IIb-IIIa interactions with integrilin: Enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate
    • Phillips DR, Teng W, Arfsten A, et al. Effect of Ca2+ on GP IIb-IIIa interactions with integrilin: enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate. Circulation 1997;96:1488-94.
    • (1997) Circulation , vol.96 , pp. 1488-1494
    • Phillips, D.R.1    Teng, W.2    Arfsten, A.3
  • 17
    • 0031744905 scopus 로고    scopus 로고
    • In vivo efficacy of SM-20302, a GP IIb/IIIa receptor antagonist, correlates with ex vivo platelet inhibition in heparinized blood but not in citrated blood
    • Rebello SS, Huang JB, Saito K, et al. In vivo efficacy of SM-20302, a GP IIb/IIIa receptor antagonist, correlates with ex vivo platelet inhibition in heparinized blood but not in citrated blood. Arterioscler Thromb Vasc Biol 1998;18:954-60.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 954-960
    • Rebello, S.S.1    Huang, J.B.2    Saito, K.3
  • 18
    • 0032552978 scopus 로고    scopus 로고
    • Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency: Implications for assay methodology and comparison of different antagonists
    • Storey RF, Wilcox RG, Heptinstall S. Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency: implications for assay methodology and comparison of different antagonists. Circulation 1998;98:1616-21.
    • (1998) Circulation , vol.98 , pp. 1616-1621
    • Storey, R.F.1    Wilcox, R.G.2    Heptinstall, S.3
  • 19
    • 0029782279 scopus 로고    scopus 로고
    • Pharmacodynamics of ticlopidine: Relation between dose and time of administration to platelet inhibition
    • Kuzniar J, Splawinska B, Malinga K, et al. Pharmacodynamics of ticlopidine: relation between dose and time of administration to platelet inhibition. Int J Clin Pharmacol Ther 1996;34:357-61.
    • (1996) Int J Clin Pharmacol Ther , vol.34 , pp. 357-361
    • Kuzniar, J.1    Splawinska, B.2    Malinga, K.3
  • 20
    • 0022002270 scopus 로고
    • Functionally thrombasthenic state in normal platelets following the administration of ticlopidine
    • DiMinno G, Cerbone AM, Mattioli PL, et al. Functionally thrombasthenic state in normal platelets following the administration of ticlopidine. J Clin Invest 1985;75:328-38.
    • (1985) J Clin Invest , vol.75 , pp. 328-338
    • DiMinno, G.1    Cerbone, A.M.2    Mattioli, P.L.3
  • 21
    • 9044234402 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty
    • Kereiakes DJ, Kleiman NS, Ambrose J, et al. Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty. J Am Coll Cardiol 1996;27:536-42.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 536-542
    • Kereiakes, D.J.1    Kleiman, N.S.2    Ambrose, J.3
  • 22
    • 0345553953 scopus 로고    scopus 로고
    • Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina: The Canadian lamifiban study
    • Theroux P, Kouz S, Roy L, et al. Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina: the Canadian lamifiban study. Circulation 1996;94:899-905.
    • (1996) Circulation , vol.94 , pp. 899-905
    • Theroux, P.1    Kouz, S.2    Roy, L.3
  • 23
    • 0028117857 scopus 로고
    • Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty
    • Tcheng JE, Ellis SG, George BS, et al. Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty. Circulation 1994;90:1757-64.
    • (1994) Circulation , vol.90 , pp. 1757-1764
    • Tcheng, J.E.1    Ellis, S.G.2    George, B.S.3
  • 24
    • 0028811436 scopus 로고
    • Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention
    • Harrington RA, Kleiman NS, Kottke-Marchant K, et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention. Am J Cardiol 1995;76:1222-7.
    • (1995) Am J Cardiol , vol.76 , pp. 1222-1227
    • Harrington, R.A.1    Kleiman, N.S.2    Kottke-Marchant, K.3
  • 25
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T-K, Hung DT, Wheaton VI, et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991;64:1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.-K.1    Hung, D.T.2    Wheaton, V.I.3
  • 26
    • 0027960284 scopus 로고
    • Molecular mechanisms of thrombin signaling
    • Coughlin SR. Molecular mechanisms of thrombin signaling. Semin Hematol 1994;31:270-7.
    • (1994) Semin Hematol , vol.31 , pp. 270-277
    • Coughlin, S.R.1
  • 27
    • 0027155450 scopus 로고
    • The thrombin receptor extra-cellular domain contains sites crucial for peptide ligand-induced activation
    • Bahou WF, Coller BS, Potter CL, et al. The thrombin receptor extra-cellular domain contains sites crucial for peptide ligand-induced activation. J Clin Invest 1993;91:1405-13.
    • (1993) J Clin Invest , vol.91 , pp. 1405-1413
    • Bahou, W.F.1    Coller, B.S.2    Potter, C.L.3
  • 28
    • 0028807209 scopus 로고
    • Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus chimeric 7E3 Fab: Implications for inhibition of the internal pool of GP IIb/IIIa receptors
    • Kleiman NS, Raizner AE, Jordan R, et al. Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus chimeric 7E3 Fab: implications for inhibition of the internal pool of GP IIb/IIIa receptors. J Am Coll Cardiol 1995;26:1665-71.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1665-1671
    • Kleiman, N.S.1    Raizner, A.E.2    Jordan, R.3
  • 29
    • 0022377803 scopus 로고
    • Inhibition of dog platelet function by in vivo infusion of F(ab′)2 fragments of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor
    • Coller BS, Scudder LE. Inhibition of dog platelet function by in vivo infusion of F(ab′)2 fragments of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor. Blood 1985;66:1456-9.
    • (1985) Blood , vol.66 , pp. 1456-1459
    • Coller, B.S.1    Scudder, L.E.2
  • 30
    • 0023838863 scopus 로고
    • Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GP IIb/IIIa antibody in a canine preparation
    • Gold HK, Coller BS, Yasuda T, et al. Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GP IIb/IIIa antibody in a canine preparation. Circulation 1988;77:670-7.
    • (1988) Circulation , vol.77 , pp. 670-677
    • Gold, H.K.1    Coller, B.S.2    Yasuda, T.3
  • 31
    • 0030716817 scopus 로고    scopus 로고
    • Rapid assessment of platelet function with a modified whole-blood aggregometer in percutaneous transluminal coronary angioplasty patients receiving anti-GP IIb/IIIa therapy
    • Mascelli MA, Worley S, Veriabo NJ, et al. Rapid assessment of platelet function with a modified whole-blood aggregometer in percutaneous transluminal coronary angioplasty patients receiving anti-GP IIb/IIIa therapy. Circulation 1997;96:3860-6.
    • (1997) Circulation , vol.96 , pp. 3860-3866
    • Mascelli, M.A.1    Worley, S.2    Veriabo, N.J.3
  • 32
    • 0028926822 scopus 로고
    • Anti-GP IIb/IIIa antibodies: Powerful tools to investigate function and regulation of an integrin
    • Bachelot C, Rendu F, Gulino D. Anti-GP IIb/IIIa antibodies: powerful tools to investigate function and regulation of an integrin. Semin Thromb Hemost 1995;21:23-36.
    • (1995) Semin Thromb Hemost , vol.21 , pp. 23-36
    • Bachelot, C.1    Rendu, F.2    Gulino, D.3
  • 33
    • 0029826510 scopus 로고    scopus 로고
    • Selective induction of a glycoprotein IIIa ligand-induced binding site by fibrinogen and von Willebrand factor
    • Mondoro TH, Wall CD, White MM, et al. Selective induction of a glycoprotein IIIa ligand-induced binding site by fibrinogen and von Willebrand factor. Blood 1996;88:3824-30.
    • (1996) Blood , vol.88 , pp. 3824-3830
    • Mondoro, T.H.1    Wall, C.D.2    White, M.M.3
  • 34
    • 0001960590 scopus 로고    scopus 로고
    • Monitoring platelet GP IIb/IIIa antagonist therapy
    • Coller BS. Monitoring platelet GP IIb/IIIa antagonist therapy. Circulation 1998;97:5-9.
    • (1998) Circulation , vol.97 , pp. 5-9
    • Coller, B.S.1
  • 35
    • 0021815571 scopus 로고
    • Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation
    • Kang YG, Martin DJ, Marquez J, et al. Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation. Anesth Analg 1985;64:888-96.
    • (1985) Anesth Analg , vol.64 , pp. 888-896
    • Kang, Y.G.1    Martin, D.J.2    Marquez, J.3
  • 36
    • 0031016637 scopus 로고    scopus 로고
    • A modified thromboelastographic method for monitoring c7E3 Fab in heparinized patients
    • Greilich PE, Alving BM, O'Neill KL, et al. A modified thromboelastographic method for monitoring c7E3 Fab in heparinized patients. Anesth Analg 1997;84:31-8.
    • (1997) Anesth Analg , vol.84 , pp. 31-38
    • Greilich, P.E.1    Alving, B.M.2    O'Neill, K.L.3
  • 37
    • 0027394454 scopus 로고
    • Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets
    • Alevriadou BR, Moake JL, Turner NA, et al. Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets. Blood 1993;81:1263-76.
    • (1993) Blood , vol.81 , pp. 1263-1276
    • Alevriadou, B.R.1    Moake, J.L.2    Turner, N.A.3
  • 38
    • 0028910738 scopus 로고
    • Platelet adhesion and aggregation on human type VI collagen surfaces under physiological flow conditions
    • Ross JM, McIntire LV, Moake JL, et al. Platelet adhesion and aggregation on human type VI collagen surfaces under physiological flow conditions. Blood 1995;85:1826-35.
    • (1995) Blood , vol.85 , pp. 1826-1835
    • Ross, J.M.1    McIntire, L.V.2    Moake, J.L.3
  • 39
    • 0025270361 scopus 로고
    • Aurintricarboxylic acid in a canine model of coronary artery thrombosis
    • Strony J, Phillips M, Brands D, et al. Aurintricarboxylic acid in a canine model of coronary artery thrombosis. Circulation 1990;81:1106-14.
    • (1990) Circulation , vol.81 , pp. 1106-1114
    • Strony, J.1    Phillips, M.2    Brands, D.3
  • 40
    • 0028910756 scopus 로고
    • Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty
    • Konstantopoulos K, Kamat SG, Schafer AI, et al. Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty. Circulation 1995;91:1427-31.
    • (1995) Circulation , vol.91 , pp. 1427-1431
    • Konstantopoulos, K.1    Kamat, S.G.2    Schafer, A.I.3
  • 41
    • 0028100628 scopus 로고
    • Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis: Relative contribution of fibrin(ogen) and platelets
    • Mailhac A, Badimon JJ, Fallon JT, et al. Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis: relative contribution of fibrin(ogen) and platelets. Circulation 1994;90:988-96.
    • (1994) Circulation , vol.90 , pp. 988-996
    • Mailhac, A.1    Badimon, J.J.2    Fallon, J.T.3
  • 42
    • 0028923012 scopus 로고
    • Comparative real-time effects on platelet adhesion and aggregation under flowing conditions of in vivo aspirin, heparin, and monoclonal antibody fragment against glycoprotein IIb-IIIa
    • Turner NA, Moake JL, Kamat SG, et al. Comparative real-time effects on platelet adhesion and aggregation under flowing conditions of in vivo aspirin, heparin, and monoclonal antibody fragment against glycoprotein IIb-IIIa. Circulation 1995;91:1354-62.
    • (1995) Circulation , vol.91 , pp. 1354-1362
    • Turner, N.A.1    Moake, J.L.2    Kamat, S.G.3
  • 43
    • 0018855854 scopus 로고
    • The electronic aggregometer: A novel device for assessing platelet behavior in blood
    • Cardinal DC, Flower RJ. The electronic aggregometer: a novel device for assessing platelet behavior in blood. J Pharmacol Methods 1980;3:135-58.
    • (1980) J Pharmacol Methods , vol.3 , pp. 135-158
    • Cardinal, D.C.1    Flower, R.J.2
  • 44
    • 0022650427 scopus 로고
    • Critical evaluation of platelet aggregation in whole human blood
    • Riess H, Braun G, Brehm G, et al. Critical evaluation of platelet aggregation in whole human blood. Am J Clin Pathol 1986;85:50-6.
    • (1986) Am J Clin Pathol , vol.85 , pp. 50-56
    • Riess, H.1    Braun, G.2    Brehm, G.3
  • 45
    • 0024440662 scopus 로고
    • Whole blood aggregometry: Influence of sample collection and delay in study performance on test results
    • Sweeney JD, Hoernig LA, Michnik A, et al. Whole blood aggregometry: influence of sample collection and delay in study performance on test results. Am J Clin Pathol 1989;92:676-9.
    • (1989) Am J Clin Pathol , vol.92 , pp. 676-679
    • Sweeney, J.D.1    Hoernig, L.A.2    Michnik, A.3
  • 46
    • 0024578359 scopus 로고
    • Ability of whole blood aggregometer to detect platelet hyperaggregability
    • Abbate R, Boddi M, Prisco D, et al. Ability of whole blood aggregometer to detect platelet hyperaggregability. Am J Clin Pathol 1989;91:159-64.
    • (1989) Am J Clin Pathol , vol.91 , pp. 159-164
    • Abbate, R.1    Boddi, M.2    Prisco, D.3
  • 47
    • 0026070916 scopus 로고
    • Platelet aggregation in platelet-rich plasma and whole blood in 120 patients with myeloproliferative disorders
    • Balduini CL, Bertolino G, Noris P, et al. Platelet aggregation in platelet-rich plasma and whole blood in 120 patients with myeloproliferative disorders. Am J Clin Pathol 1991;95:82-6.
    • (1991) Am J Clin Pathol , vol.95 , pp. 82-86
    • Balduini, C.L.1    Bertolino, G.2    Noris, P.3
  • 48
    • 0001356033 scopus 로고    scopus 로고
    • Preclinical development of c7E3 Fab: A mouse/human chimeric monoclonal antibody fragment that inhibits platelet function by blockade of GP IIb/IIIa receptors with observations on the immunogenicity of c7E3 Fab in humans
    • Horton MA, editor. Boca Raton, Fla: CRC Press
    • Jordan RE, Wagner CL, Mascelli MA, et al. Preclinical development of c7E3 Fab: a mouse/human chimeric monoclonal antibody fragment that inhibits platelet function by blockade of GP IIb/IIIa receptors with observations on the immunogenicity of c7E3 Fab in humans. In: Horton MA, editor. Adhesion receptors as therapeutic targets. Boca Raton, Fla: CRC Press; 1996. p. 281-305.
    • (1996) Adhesion Receptors As Therapeutic Targets , pp. 281-305
    • Jordan, R.E.1    Wagner, C.L.2    Mascelli, M.A.3
  • 49
    • 0028609229 scopus 로고
    • Abciximab (c7E3 Fab): A review of its pharmacology and therapeutic potential in ischaemic heart disease
    • Faulds D, Sorkin EM. Abciximab (c7E3 Fab): a review of its pharmacology and therapeutic potential in ischaemic heart disease. Drugs 1994;48:583-98.
    • (1994) Drugs , vol.48 , pp. 583-598
    • Faulds, D.1    Sorkin, E.M.2
  • 50
    • 0032485876 scopus 로고    scopus 로고
    • Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade
    • Mascelli MA, Lance ET, Damaraju L, et al. Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade. Circulation 1998;97:1680-8.
    • (1998) Circulation , vol.97 , pp. 1680-1688
    • Mascelli, M.A.1    Lance, E.T.2    Damaraju, L.3
  • 51
    • 23444458293 scopus 로고
    • Randomized trial of a GP IIb/IIIa platelet receptor blocker in refractory unstable angina
    • Simoons ML, de Boer MJ, van den Brand MJ, et al. Randomized trial of a GP IIb/IIIa platelet receptor blocker in refractory unstable angina. Circulation 1994;89:596-603.
    • (1994) Circulation , vol.89 , pp. 596-603
    • Simoons, M.L.1    De Boer, M.J.2    Van Den Brand, M.J.3
  • 52
    • 0030918995 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study
    • CAPTURE Investigators
    • CAPTURE Investigators. Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE study. Lancet 1997;349:1429-35.
    • (1997) Lancet , vol.349 , pp. 1429-1435
  • 53
    • 4243461993 scopus 로고    scopus 로고
    • Synergy of abciximab and ticlopidine in patients undergoing intracoronary stenting
    • abstract
    • Kleiman NS, Graziadei N, Lance E, et al. Synergy of abciximab and ticlopidine in patients undergoing intracoronary stenting [abstract]. J Am Coll Cardiol 1998;31(suppl A):238A.
    • (1998) J Am Coll Cardiol , vol.31 , Issue.SUPPL. A
    • Kleiman, N.S.1    Graziadei, N.2    Lance, E.3
  • 54
    • 0027449969 scopus 로고
    • Shear-induced platelet aggregation is potentiated by desmopressin and inhibited by ticlopidine
    • Cattaneo M, Lombardi R, Bettega D, et al. Shear-induced platelet aggregation is potentiated by desmopressin and inhibited by ticlopidine. Arterioscler Thromb 1993;13:393-7.
    • (1993) Arterioscler Thromb , vol.13 , pp. 393-397
    • Cattaneo, M.1    Lombardi, R.2    Bettega, D.3
  • 55
    • 0032055447 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with ticlopidine: A review of 60 cases
    • Bennett CL, Weinberg PD, Rozenberg-Ben-Dror K, et al. Thrombotic thrombocytopenic purpura associated with ticlopidine: a review of 60 cases. Ann Intern Med 1998;128:541-4.
    • (1998) Ann Intern Med , vol.128 , pp. 541-544
    • Bennett, C.L.1    Weinberg, P.D.2    Rozenberg-Ben-Dror, K.3
  • 56
    • 0032005728 scopus 로고    scopus 로고
    • Abciximab and excessive bleeding in patients undergoing emergency cardiac operations
    • Gammie JS, Zenati M, Kormos RL, et al. Abciximab and excessive bleeding in patients undergoing emergency cardiac operations. Ann Thorac Surg 1998;65:465-9.
    • (1998) Ann Thorac Surg , vol.65 , pp. 465-469
    • Gammie, J.S.1    Zenati, M.2    Kormos, R.L.3
  • 57
    • 0031195044 scopus 로고    scopus 로고
    • Routine platelet transfusion in patients undergoing emergency coronary bypass surgery after receiving abciximab
    • Juergens CP, Yeung AC, Oesterle SN. Routine platelet transfusion in patients undergoing emergency coronary bypass surgery after receiving abciximab. Am J Cardiol 1997;80:74-5.
    • (1997) Am J Cardiol , vol.80 , pp. 74-75
    • Juergens, C.P.1    Yeung, A.C.2    Oesterle, S.N.3
  • 58
    • 0025887032 scopus 로고
    • Barbourin: A GP IIb-IIIa-specific integrin antagonist from the venom of Sistrurus m barbouri
    • Scarborough RM, Rose JW, Hsu MA, et al. Barbourin: a GP IIb-IIIa-specific integrin antagonist from the venom of Sistrurus m barbouri. J Biol Chem 1991;266:9359-62.
    • (1991) J Biol Chem , vol.266 , pp. 9359-9362
    • Scarborough, R.M.1    Rose, J.W.2    Hsu, M.A.3
  • 59
    • 0027508996 scopus 로고
    • Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms
    • Scarborough RM, Rose JW, Naughton MA, et al. Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms. J Biol Chem 1993;268:1058-65.
    • (1993) J Biol Chem , vol.268 , pp. 1058-1065
    • Scarborough, R.M.1    Rose, J.W.2    Naughton, M.A.3
  • 61
    • 0030919511 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
    • IMPACT-II Investigators
    • IMPACT-II Investigators. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet 1997;349:1422-8.
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 62
    • 0000808672 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade with high-dose Integrilin in coronary intervention: Results of the PRIDE study
    • abstract
    • Tcheng JE, Thel MC, Jennings L, et al. Platelet glycoprotein IIb/IIIa receptor blockade with high-dose Integrilin in coronary intervention: results of the PRIDE study [abstract]. Eur Heart J 1997;18:624.
    • (1997) Eur Heart J , vol.18 , pp. 624
    • Tcheng, J.E.1    Thel, M.C.2    Jennings, L.3
  • 63
    • 0008926519 scopus 로고    scopus 로고
    • Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes
    • PURSUIT Trial Investigators
    • PURSUIT Trial Investigators. Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med 1998;339:436-43.
    • (1998) N Engl J Med , vol.339 , pp. 436-443
  • 64
    • 0001429650 scopus 로고    scopus 로고
    • Tirofiban, a nonpeptide inhibitor of the platelet glycoprotein IIb/IIIA receptor
    • Sasahara AA, Loscalzo J, editors. New York, NY: Marcel Dekker
    • Deckelbaum LI, Sax FL, Grossman W. Tirofiban, a nonpeptide inhibitor of the platelet glycoprotein IIb/IIIA receptor. In: Sasahara AA, Loscalzo J, editors. New therapeutic agents in thrombosis and thrombolysis. New York, NY: Marcel Dekker; 1997. p. 355-65.
    • (1997) New Therapeutic Agents in Thrombosis and Thrombolysis , pp. 355-365
    • Deckelbaum, L.I.1    Sax, F.L.2    Grossman, W.3
  • 65
    • 0027961072 scopus 로고
    • Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men
    • Barrett JS, Murphy G, Peerlinck K, et al. Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men. Clin Pharmacol Ther 1994;56:377-88.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 377-388
    • Barrett, J.S.1    Murphy, G.2    Peerlinck, K.3
  • 66
    • 0007953158 scopus 로고
    • A heparin-controlled study of MK-383 in unstable angina
    • abstract
    • Theroux P, White H, David D, et al. A heparin-controlled study of MK-383 in unstable angina [abstract]. Circulation 1994;90:I-231.
    • (1994) Circulation , vol.90
    • Theroux, P.1    White, H.2    David, D.3
  • 67
    • 0032560628 scopus 로고    scopus 로고
    • International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina
    • PARAGON Investigators
    • PARAGON Investigators. International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina. Circulation 1998;97:2386-95.
    • (1998) Circulation , vol.97 , pp. 2386-2395


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.