Reduction of the ring size of radiolabeled lactam bridge-cyclized α-MSH peptide, resulting in enhanced melanoma uptake

Journal of Nuclear Medicine

Volumn 51, Issue 3, 2010, Pages 418-426

  Guo, Haixun ^a   Yang, Jianquan ^a   Gallazzi, Fabio ^b   Miao, Yubin ^a,c,d  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

melanocyte stimulating hormone; Melanoma imaging; Radiolabeled cyclic peptide; Small animal imaging

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID NLE C[ASPARTYLHISTIDYLPHENYLALANYLARGINYLTRYPTOPHYLLYSINE]CONH2 INDIUM IN 111; ALPHA INTERMEDIN; UNCLASSIFIED DRUG; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 1,4,7,10-TETRAAZACYCLODODECANE- 1,4,7,10-TETRAACETIC ACID; CHELATING AGENT; DIAGNOSTIC AGENT; INDIUM; LACTAM; MELANOCORTIN 1 RECEPTOR; SINGLE HETEROCYCLIC RINGS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FEMALE; INTERNALIZATION; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RECEPTOR BINDING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; URINARY TRACT; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; COMPUTER ASSISTED TOMOGRAPHY; CYCLIZATION; METABOLISM; RADIOGRAPHY; SCINTISCANNING; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CHELATING AGENTS; CYCLIZATION; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; INDIUM RADIOISOTOPES; LACTAMS; MELANOMA; MICE; RECEPTOR, MELANOCORTIN, TYPE 1; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77950362823     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.071787     Document Type: Article

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