Catalytic asymmetric nitro-Mannich reactions with a Yb/K heterobimetallic catalyst

Molecules

Volumn 15, Issue 3, 2010, Pages 1280-1290

  Nitabaru, Tatsuya ^a   Kumagai, Naoya ^a   Shibasaki, Masakatsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Amidebased ligand; Asymmetric catalysis; Heterobimetallic; Nitro Mannich; Ytterbium

Indexed keywords

METAL; POTASSIUM; YTTERBIUM;

ARTICLE; CATALYSIS; CHEMISTRY; HYDROGEN BOND; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

CATALYSIS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; METALS; POTASSIUM; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM; YTTERBIUM;

EID: 77950353969     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15031280     Document Type: Article

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42. 1H-NMR, anti/syn = 2.6/1), strongly suggested that unidentified achiral basic species promoted the background reaction to decrease the stereoselectivity.
43. The identical reaction in Table 5, entry 3 gave the product 3ca after 20 h in 62% yield anti/syn = 18/1, 85% ee (anti), indicating the absence of retro-reaction and epimerization of the product during the reaction.