The first catalytic asymmetric nitro-Mannich-type reaction promoted by a new heterobimetallic complex

Angewandte Chemie - International Edition

Volumn 38, Issue 23, 1999, Pages 3504-3506

  Yamada, Ken Ichi ^a   Harwood, Simon J ^a   Gröger, Harald ^a   Shibasaki, Masakatsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Asymmetric catalysis; Asymmetric synthesis; Diamines; Imines; Nitroalkanes

Indexed keywords

DIAMINE; IMINE; METAL COMPLEX; NITROALKANE;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL REACTION; STOICHIOMETRY; SYNTHESIS;

EID: 0033521210     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991203)38:23<3504::AID-ANIE3504>3.0.CO;2-E     Document Type: Article

References (38)

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26. 2, (1.0M, 0.55 mL) was added dropwise to the cooled mixture (over ca. 5 min). After the removal of the ice-water bath, the mixture was stirred for 2 h at room temperature, and then diluted with toluene (ca. 20 mL). The mixture was transferred into a 200-mL flask, and was diluted with further toluene (ca. 75 mL). The suspension was then filtered through celite, and the celite was washed with toluene. Evaporation of the solvent gave a brown oil containing mainly the imine 1a and benzaldehyde. The excess benzaldehyde was removed under high vacuum, and recrystallization of the resulting solid provided the imine 1a (0.26 g, 85%).
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