Selective regulation of aromatase expression for drug discovery

Journal of Steroid Biochemistry and Molecular Biology

Volumn 118, Issue 4-5, 2010, Pages 207-210

  Brueggemeier, Robert W ^a,b   Su, Bin ^a,b   Darby, Michael V ^a,b   Sugimoto, Yasuro ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Aromatase; COX 2 inhibitors; SiRNA; Sulfonanilides

Indexed keywords

AROMATASE; AROMATASE INHIBITOR; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; SULFONANILIDE; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; SMALL INTERFERING RNA; SULFONAMIDE;

APOPTOSIS; BREAST CANCER; CANCER CELL; COMBINATORIAL CHEMISTRY; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; ESTROGEN SYNTHESIS; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; PHARMACOPHORE; REAL TIME POLYMERASE CHAIN REACTION; STRUCTURE ACTIVITY RELATION; ARTICLE; BREAST TUMOR; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TUMOR CELL LINE;

ANILINE COMPOUNDS; AROMATASE; AROMATASE INHIBITORS; BREAST NEOPLASMS; CELL LINE, TUMOR; CYCLOOXYGENASE 2 INHIBITORS; DRUG DISCOVERY; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR STRUCTURE; RNA, SMALL INTERFERING; SULFONAMIDES;

EID: 77950350192     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2009.11.009     Document Type: Conference Paper

References (16)

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