20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 298, Issue 4, 2010, Pages

  Bodiga, Sreedhar ^a   Gruenloh, Stephanie K ^a   Gao, Ying ^a   Manthati, Vijay L ^b   Dubasi, Narsimhaswamy ^b   Falck, John R ^b   Medhora, Meetha ^a   Jacobs, Elizabeth R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Endothelial nitric oxide synthase; Hydrogen peroxide; Pulmonary endothelium; Superoxide

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 20 HYDROXYICOSATETRAENOIC ACID; APOCYNIN; CATALASE; DIAMINOFLUORESCEIN; DICHLOROFLUORESCEIN; DIHYDRORHODAMINE 123; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUORESCEIN DERIVATIVE; GLYCOPROTEIN GP 91; HYDROGEN PEROXIDE; MACROGOL; NITRIC OXIDE; PEROXYNITRITE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERINE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATTLE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FLUORESCENCE; HYDROGEN PEROXIDE; HYDROXYEICOSATETRAENOIC ACIDS; INTRACELLULAR SPACE; MODELS, BIOLOGICAL; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PEROXYNITROUS ACID; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ARTERY;

EID: 77950334333     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00298.2009     Document Type: Article

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