Cardiac dysfunction in HgCl2-induced nephrotic syndrome

Experimental Biology and Medicine

Volumn 235, Issue 3, 2010, Pages 392-400

  Moreira Rodrigues, Mónica ^a   Henriques Coelho, Tiago ^b   Moura, Cláudia ^b   Vasques Nóvoa, Francisco ^b   Sampaio Maia, Benedita ^a,c   Pestana, Manuel ^a,d   Leite Moreira, Adelino F ^b  

^a Cardiovascular Research and Development Unit   (Portugal)

^b Institute of Histology and Embryology   (Portugal)

^c U Porto   (Portugal)

^d HOSPITAL DE SÃO JOÃO   (Portugal)

Author keywords

Cardiac atrophy; Heart function; HgCl2; Nephrotic syndrome; Noradrenaline; Proteinuria; Sodium retention; Systemic autoimmune disease

Indexed keywords

ALBUMIN; CREATININE; MERCURIC CHLORIDE; NORADRENALIN; SODIUM;

ALBUMINURIA; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASCITES; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DISEASE MODEL; ECHOCARDIOGRAPHY; GASTROCNEMIUS MUSCLE; HEART BEAT; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE FIBROSIS; HYPERLIPIDEMIA; MALE; MORPHOMETRICS; MUSCLE MASS; NEPHROTIC SYNDROME; NONHUMAN; PROTEINURIA; RAT; SODIUM RETENTION; TIBIA SHAFT; URINARY EXCRETION; ANIMAL; ATROPHY; AUTOIMMUNE DISEASE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; FIBROSIS; HEART; HEART DISEASE; HEART MUSCLE; HEMODYNAMICS; PATHOLOGY; PATHOPHYSIOLOGY; TIME;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; APOPTOSIS; ATROPHY; AUTOIMMUNE DISEASES; FIBROSIS; HEART; HEART DISEASES; HEMODYNAMICS; MALE; MERCURIC CHLORIDE; MYOCARDIUM; NEPHROTIC SYNDROME; NOREPINEPHRINE; RATS; SODIUM; TIME FACTORS;

EID: 77950229810     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2009.009147     Document Type: Article

References (40)

1. Bigazzi PE. Metals and kidney autoimmunity. Environ Health Perspect 1999;107:753-765
2. Deschenes G, Doucet A. Collecting duct (Na+/K+)-ATPase activity is correlated with urinary sodium excretion in rat nephrotic syndromes. J Am Soc Nephrol 2000;11:604-615
3. 2 in the Brown-Norway rat. Ann Immunol (Paris) 1978;129 C:777-792
4. Kanfer A. Coagulation factors in nephrotic syndrome. Am J Nephrol 1990;10 (Suppl. 1):63-68
5. Michaud A, Sapin C, Leca G, Aiach M, Druet P. Involvement of hemostasis during an autoimmune glomerulonephritis induced by mercuric chloride in Brown-Norway rats. Thromb Res 1984;33:77-88
6. 2-induced membranous nephropathy. Life Sci 2006;78:1246-1255
7. Nangaku M, Couser WG. Mechanisms of immune-deposit formation and the mediation of immune renal injury. Clin Exp Nephrol 2005;9:183-191
8. Suzuki K, Kanabayashi T, Nakayama H, Doi K. Kinetics of chemokines and their receptors in mercuric chloride-induced tubulointerstitial lesions in Brown-Norway rats. Exp Mol Pathol 2003;75:58-67
9. Adedoyin O, Frank R, Vento S, Vergara M, Gauthier B, Trachtman H. Cardiac disease in children with primary glomerular disorders-role of focal segmental glomerulosclerosis. Pediatr Nephrol (Berlin, Germany) 2004;19:408-412
10. Ordonez JD, Hiatt RA, Killebrew EJ, Fireman BH. The increased risk of coronary heart disease associated with nephrotic syndrome. Kidney Int 1993;44:638-642
11. Watts GF, Herrmann S, Dogra GK, Playford DA, Best JD, Thomas MA, Irish A. Vascular function of the peripheral circulation in patients with nephrosis. Kidney Int 2001;60:182-189
12. Ritz E, Dikow R, Ruilope LM. Renal dysfunction as a cardiovascular risk factor. Curr Hypertens Rep 2002;4:365-368
13. Segura J, Campo C, Ruilope LM. Proteinuria: an underappreciated risk factor in cardiovascular disease. Curr Cardiol Rep 2002;4:458-462
14. Avalos I, Rho YH, Chung CP, Stein CM. Atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus. Clin Exp Rheumatol 2008;26:S5-13
15. Moreira-Rodrigues M, Roncon-Albuquerque R Jr, Henriques-Coelho T, Lourenco AP, Sampaio-Maia B, Santos J, Pestana M, Leite-Moreira AF. Cardiac remodeling and dysfunction in nephrotic syndrome. Kidney Int 2007;71:1240-1248
16. van der Vijgh WJ, Van Velzen D, Van der Poort JS, Schluper HM, Mross K, Feijen J, Pinedo HM. Morphometric study of myocardial changes during puromycin aminonucleoside induced nephropathy in rats. Anticancer Res 1987;7:1111-1115
17. Gillebert TC, Leite-Moreira AF, De Hert SG. Load dependent diastolic dysfunction in heart failure. Heart Failure Rev 2000;5:345-355
18. Leite-Moreira AF, Correia-Pinto J. Load as an acute determinant of end-diastolic pressure-volume relation. Am J Physiol Heart Circ Physiol 2001;280:H51-9
19. Leite-Moreira AF, Correia-Pinto J, Gillebert TC. Afterload induced changes in myocardial relaxation: a mechanism for diastolic dysfunction. Cardiovasc Res 1999;43:344-353
20. Soares-da-Silva P, Fernandes MH, Pestana M. Studies on the role of sodium on the synthesis of dopamine in the rat kidney. J Pharmacol Exp Therapeut 1993;264:406-414
21. Sampaio-Maia B, Serrao P, Guimaraes JT, Vieira-Coelho MA, Pestana M. Renal dopaminergic system activity in the rat remnant kidney. Nephron 2005;99:e46-55
22. Bustos C, Gonzalez E, Muley R, Alonso JL, Egido J. Increase of tumour necrosis factor alpha synthesis and gene expression in peripheral blood mononuclear cells of children with idiopathic nephrotic syndrome. Eur J Clin Investig 1994;24:799-805
23. Gomez-Chiarri M, Ortiz A, Lerma JL, Lopez-Armada MJ, Mampaso F, Gonzalez E, Egido J. Involvement of tumor necrosis factor and platelet-activating factor in the pathogenesis of experimental nephrosis in rats. Lab Investig J Tech Methods Pathol 1994;70:449-459
24. Raveh D, Shemesh O, Ashkenazi YJ, Winkler R, Barak V. Tumor necrosis factor-alpha blocking agent as a treatment for nephrotic syndrome. Pediatric nephrology (Berlin, Germany) 2004;19:1281-1284
25. Suranyi MG, Guasch A, Hall BM, Myers BD. Elevated levels of tumor necrosis factor-alpha in the nephrotic syndrome in humans. Am J Kidney Dis 1993;21:251-259
26. Haffner D, Tonshoff B, Blum WF, Vickers M, Siebler T, Cronin MJ, Baxter RC, Mehls O. Insulin-like growth factors (IGFs) and IGF binding proteins, serum acid-labile subunit and growth hormone binding protein in nephrotic children. Kidney Int 1997;52:802-810
27. Thabet MA, Challa A, Chan W, Liu F, Hintz RL, Chan JC. Insulin-like growth factor and growth hormone receptor in nephrotic rats. Am J Physiol 1994;266:E102-6
28. Zhou X, Loke KY, Pillai CC, How HK, Yap HK, Lee KO. IGFs and IGF-binding proteins in short children with steroid-dependent nephrotic syndrome on chronic glucocorticoids: changes with 1 year exogenous GH. Eur J Endocrinol/Eur Fed Endocrine Soc 2001;144:237-243
29. Dong F, Ren J. Insulin-like growth factors (IGFs) and IGF-binding proteins in nephrotic syndrome children on glucocorticoid. Pharmacol Res 2003;48:319-323
30. DiBona GF. Neural control of renal tubular sodium reabsorption of the dog. Fed Proc 1978;37:1214-1217
31. Gullner HG. The role of the adrenergic nervous system in sodium and water excretion. Klinische Wochenschrift 1983;61:1063-1066
32. Beach RE, Schwab SJ, Brazy PC, Dennis VW. Norepinephrine increases Na+-K+-ATPase and solute transport in rabbit proximal tubules. Am J Physiol 1987;252:F215-20
33. Sonalker PA, Tofovic SP, Bastacky SI, Jackson EK. Chronic noradrenaline increases renal expression of NHE-3, NBC-1, BSC-1 and aquaporin-2. Clin Exp Pharmacol Physiol 2008;35:594-600
34. DiBona GF, Sawin LL, Jones SY. Characteristics of renal sympathetic nerve activity in sodium-retaining disorders. Am J Physiol 1996;271:R295-302
35. Rahman SN, Abraham WT, Van Putten VJ, Hasbargen JA, Schrier RW. Increased norepinephrine secretion in patients with the nephrotic syndrome and normal glomerular filtration rates: evidence for primary sympathetic activation. Am J Nephrol 1993;13:266-270
36. Correia-Pinto J, Henriques-Coelho T, Roncon-Albuquerque R Jr, Lourenco AP, Melo-Rocha G, Vasques-Novoa F, Gillebert TC, Leite-Moreira AF. Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension. Basic Res Cardiol 2009;104:535-545
37. Lourenco AP, Roncon-Albuquerque R Jr, Bras-Silva C, Faria B,Wieland J, Henriques-Coelho T, Correia-Pinto J, Leite-Moreira AF. Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats. Am J Physiol Heart Circ Physiol 2006;291:H1587-94
38. Egan JR, Butler TL, Au CG, Tan YM, North KN, Winlaw DS. Myocardial water handling and the role of aquaporins. Biochim Biophys Acta 2006;1758:1043-1052
39. Lee CS, Tkacs NC. Current concepts of neurohormonal activation in heart failure: mediators and mechanisms. AACN Adv Crit Care 2008;19:364-85; quiz 386-387
40. Kaysen GA, Carstensen A, Martin VI. Muscle protein synthesis is impaired in nephrotic rats. Miner Electrolyte Metab 1992;18:228-232