Tumor necrosis factor-α blocking agent as a treatment for nephrotic syndrome

Pediatric Nephrology

Volumn 19, Issue 11, 2004, Pages 1281-1284

  Raveh, David ^a   Shemesh, Ovadia ^a   Ashkenazi, Yaakov Jack ^a   Winkler, Robert ^a   Barak, Vivian ^b  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Nephrotic syndrome; Tumor necrosis factor

Indexed keywords

CHINESE DRUG; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; HERBACEOUS AGENT; INFLIXIMAB; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PENTOXIFYLLINE; PREDNISONE; STEROID; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ARTICLE; BONE NECROSIS; CASE REPORT; CELL PROLIFERATION; CLINICAL PROTOCOL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MEGADOSE; DRUG PULSE THERAPY; DRUG RESPONSE; HUMAN; LABORATORY TEST; MALE; MESANGIUM CELL; NEPHROTIC SYNDROME; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEINURIA; REMISSION; TREATMENT FAILURE;

ADOLESCENT; ANTIBODIES, MONOCLONAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; NEPHROTIC SYNDROME; REMISSION INDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 7744221493     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-004-1573-2     Document Type: Article

References (14)

1. Suranyl MG, Guasch A, Hall BM, Myers BD (1993) Elevated levels of TNFα in the nephrotic syndrome in humans. Am J Kidney Dis 22:622
2. Bakr A, Shokeir M, El-Chenawi F, El-Husseni F, Abdel-rachman A, El-Ashry R (2003) TNFα production from mononuclear cells in nephrotic syndrome. Pediatr Nephrol 18:516-520 12707837
3. McCarthy ET, Sharma R, Scharma M, Li JZ, Ge XL, Dileezpan KN (1998) TNFα increases albumin permeability of isolated rat glomeruli through the generation of superoxide. J Am Soc Nephrol 9:433-438 1:CAS:528:DyaK1cXhvVegsr4%3D, 9513905
4. Pai R, Ha H, Kirschenbaum MA, Kamanna VS (1996) Role of tumor necrosis factor alpha on mesangeal cell MCP-1 expression and monocyte migration: mechanisms mediated by signal transduction. J Am Soc Nephrol 7:914-923 1:CAS:528:DyaK28XkslWrtb0%3D, 8793801
5. Drewe E, McDermott EM, Powell RJ (2000) Treatment of the nephrotic syndrome with Etanercept in patients with the tumor necrosis factor receptor-associated periodic syndrome. N Engl J Med 343:1044-1045 10.1056/NEJM200010053431412, 1:STN:280:DC%2BD3cvnsVSksw%3D%3D, 11023397
6. Verschueren P, Lensen F, Lerut E, Claes K, De Vos R, Van Damme B, Westhovens R (2003) Benefit of anti-TNFα treatment for nephrotic syndrome in a patient with juvenile inflammatory bowel disease associated spondyloarthropathy complicated with amyloidosis and glomerulonephritis. Ann Rheum Dis 62:368-369 10.1136/ard.62.4.368, 1:STN:280:DC%2BD3s7ltVWjtw%3D%3D, 12634242
7. Pusey C (2001) Efficacy of anti-TNFα in the treatment of nephrotoxic nephritis. Symposium on glomerulonephritis and anti-GBM disease: World Congress of Nephrology (ASN), USA (http://www.hdcn.com/symp/01asn/pu/pusey.htm)
8. Bircan Z, Kara B (2003) Intravenous cyclophosphamide is the drug of choice for steroid dependent nephrotic syndrome. Pediatr Int 45:65-67 10.1046/j.1442-200X.2003.01673.x, 1:CAS:528:DC%2BD3sXktVSntbY%3D, 12654072
9. Ducloux D, Bresson-Vautrin C, Chalopin J (2001) Use of pentoxifylline in membranous nephropathy. Lancet 357:1672-1673 10.1016/S0140-6736(00)04830-3, 1:STN:280:DC%2BD3MzmtlGrsA%3D%3D, 11425374
10. Cornillie F, Shealy D, D'Haens G, Geboes K, Van Assche G, Ceuppens J, Wagner C, Schaible T, Plevy SE, Targan SR, Rutgeerts P (2001) Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease. Aliment Pharmacol Ther 15:463-473 10.1046/j.1365-2036.2001.00956.x, 1:CAS:528:DC%2BD3MXjtVyis7w%3D, 11284774
11. Barak V, Nisman B, Polliack A (1999) The tumor necrosis factor family and correlation with disease activity and response to treatment in hairy cell leukemia. Eur J Haematol 62:71-75 1:STN:280:DyaK1M7mtVSksQ%3D%3D, 10052708
12. Li Naisan Yu Dondhui (1992) Study on toxicokinetics of crude extract from Tripterygium wilfordii. J Chin Phram Univ 23:25-26
13. Zhang Xiao Chen Shunle (1993) Effect of Tripterygium wilfordii Hook F on contrasuppressor T cells in SLE nephritic patients. Chin J Immunol 9:230-231
14. Qiu D, Kao PN (2003) Immunosuppressive and anti-inflammatory mechanisms of Triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. F. Drugs 4:1-18 10.1159/000070527, 1:CAS:528:DC%2BD3sXhvFCitL4%3D