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Volumn 61, Issue 1, 2010, Pages 1-9

Assessment of cyto/genotoxicity of irinotecan in V79 cells using the comet, micronucleus, and chromosome aberration assay

Author keywords

Alkaline comet assay; Antineoplastic drug; Cell cultures; DNA and cytogenetic damage

Indexed keywords

DNA; IRINOTECAN;

EID: 77950210647     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: 10.2478/10004-1254-61-2010-1967     Document Type: Article
Times cited : (9)

References (34)
  • 1
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase i
    • Hsiang YH, Hertzberg R, Hecht S, Liu LF. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985;260:14873-14878
    • (1985) J Biol Chem , vol.260
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 2
    • 0023924786 scopus 로고
    • Identifi cation of mammalian DNA topoisomerase i as an intracellular target of the anticancer drug camptothecin
    • Hsiang YH, Liu LF. Identifi cation of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 1988;48:1722-1726
    • (1988) Cancer Res , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 3
    • 0024324205 scopus 로고
    • On the mechanism of topoisomerase i inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex
    • Hertzberg RP, Caranfa MJ, Hecht SM. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry 1989;28:4629-4638
    • (1989) Biochemistry , vol.28 , pp. 4629-4638
    • Hertzberg, R.P.1    Caranfa, M.J.2    Hecht, S.M.3
  • 4
    • 0027092752 scopus 로고
    • Camptothecin inhibits both the cleavage and religation reactions of eucaryotic DNA topoisomerase i
    • Kjeldsen E, Svejstrup JQ, Gromova H, Alsner J, Westergaard O. Camptothecin inhibits both the cleavage and religation reactions of eucaryotic DNA topoisomerase I. J Mol Biol 1992;228:1025-1030
    • (1992) J Mol Biol , vol.228 , pp. 1025-1030
    • Kjeldsen, E.1    Svejstrup, J.Q.2    Gromova, H.3    Alsner, J.4    Westergaard, O.5
  • 5
    • 0037212083 scopus 로고    scopus 로고
    • Homocamptothecins: Potent topoisomerase i inhibitors and promising anticancer drugs
    • Bailly C. Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs. Crit Rev Oncol Hematol 2003;45:91-108.
    • (2003) Crit Rev Oncol Hematol , vol.45 , pp. 91-108
    • Bailly, C.1
  • 6
    • 0024229066 scopus 로고
    • Evidence that DNA topoisomerase i is necessary for the cytotoxic effects of camptothecin
    • Eng WK, Faucette L, Johnson RK, Sternglanz R. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Mol Pharmacol 1988;34:755-760
    • (1988) Mol Pharmacol , vol.34 , pp. 755-760
    • Eng, W.K.1    Faucette, L.2    Johnson, R.K.3    Sternglanz, R.4
  • 9
    • 0015451631 scopus 로고
    • Action of camptothecin on mammalian cells in culture
    • Li LH, Fraser TJ, Olin EJ, Bhuyan BK. Action of camptothecin on mammalian cells in culture. Cancer Res 1972;32:2643-2650
    • (1972) Cancer Res , vol.32 , pp. 2643-2650
    • Li, L.H.1    Fraser, T.J.2    Olin, E.J.3    Bhuyan, B.K.4
  • 10
    • 77950255331 scopus 로고    scopus 로고
    • Irinotecan. USP DI., . 20th ed. Englewood (CO): Micromedex Inc.
    • Irinotecan. USP DI. Vol.1, Drug information for the health care professional. 20th ed. Englewood (CO): Micromedex Inc.; 2000.
    • (2000) Drug Information for the Health Care Professionalx , vol.1
  • 11
    • 0023919963 scopus 로고
    • A simple technique for quantifi cation of low levels of DNA damage in individual cells
    • Singh N, McCoy M, Tice R, Schneider E. A simple technique for quantifi cation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.1    McCoy, M.2    Tice, R.3    Schneider, E.4
  • 12
    • 0031742751 scopus 로고    scopus 로고
    • Preclinical and clinical results with Irinotecan - Extending principles learned in model system to clinical trails design
    • Houghton PJ, Stewart CF, Thompson J, Santana VM, Furman WL, Friedman HS. Preclinical and clinical results with Irinotecan - extending principles learned in model system to clinical trails design. Oncology (Williston Park). 1998;12(8 Suppl 6):84-93.
    • (1998) Oncology (Williston Park) , vol.12 , Issue.8 SUPPL. 6 , pp. 84-93
    • Houghton, P.J.1    Stewart, C.F.2    Thompson, J.3    Santana, V.M.4    Furman, W.L.5    Friedman, H.S.6
  • 13
    • 0027243234 scopus 로고
    • DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells
    • Yoshida A, Ueda T, Wano Y, Nakamura T. DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells. Jpn J Cancer Res 1993;84:566-573
    • (1993) Jpn J Cancer Res , vol.84 , pp. 566-573
    • Yoshida, A.1    Ueda, T.2    Wano, Y.3    Nakamura, T.4
  • 15
    • 0242720478 scopus 로고    scopus 로고
    • Camptothecin-induced apoptosis in non-small cell lung cancer is independent on cyclooxygenase expression
    • Sanchez-Alcazar JA, Bradbury DA, Brea-Calvo G, Navas P, Knox AJ. Camptothecin-induced apoptosis in non-small cell lung cancer is independent on cyclooxygenase expression. Apoptosis 2003;8:639-647
    • (2003) Apoptosis , vol.8 , pp. 639-647
    • Sanchez-Alcazar, J.A.1    Bradbury, D.A.2    Brea-Calvo, G.3    Navas, P.4    Knox, A.J.5
  • 16
    • 0032894872 scopus 로고    scopus 로고
    • Synergistic cytotoxicity, apoptosis and protein linked DNA breakage by etoposiDe and camptothecin in human U87 glioma cells: Dependence on tyrosine phosphorilation
    • Ciesielski MJ, Fenstermaker RA. Synergistic cytotoxicity, apoptosis and protein linked DNA breakage by etoposiDe and camptothecin in human U87 glioma cells: dependence on tyrosine phosphorilation. J Neurooncol 1999;41:223-234
    • (1999) J Neurooncol , vol.41 , pp. 223-234
    • Ciesielski, M.J.1    Fenstermaker, R.A.2
  • 17
    • 21344454905 scopus 로고    scopus 로고
    • In vitro and in vivo irinotecan-induced changes in expression profi les of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells
    • Minderman H, Conroy JM, O Loughlin KL, McQuaid D, Quinn P, Li S, Pendyala L, Nowak NJ, Baer MR. In vitro and in vivo irinotecan-induced changes in expression profi les of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells. Mol Cancer Therap 2005;4:885-900.
    • (2005) Mol Cancer Therap , vol.4 , pp. 885-900
    • Minderman, H.1    Conroy, J.M.2    Loughlin K L, O.3    McQuaid, D.4    Quinn, P.5    Li, S.6    Pendyala, L.7    Nowak, N.J.8    Baer, M.R.9
  • 18
    • 0034773290 scopus 로고    scopus 로고
    • Combination of oxaliplatin and irinotecan on human colon cancer cell lines: Activity in vitro and in vivo
    • Guichard S, Arnould S, Hennebelle I, Bugat R, Canal P. Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo. Anti-Cancer Drugs 2001;12:741-751
    • (2001) Anti-Cancer Drugs , vol.12 , pp. 741-751
    • Guichard, S.1    Arnould, S.2    Hennebelle, I.3    Bugat, R.4    Canal, P.5
  • 19
    • 0141618280 scopus 로고    scopus 로고
    • Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer
    • Gibson RJ, Bowen JM, Inglis MR, Cummins AG, Keefe DM. Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer. J Gastroentrol Hepatol 2003;18:1095-1100
    • (2003) J Gastroentrol Hepatol , vol.18 , pp. 1095-1100
    • Gibson, R.J.1    Bowen, J.M.2    Inglis, M.R.3    Cummins, A.G.4    Keefe, D.M.5
  • 20
    • 0036907234 scopus 로고    scopus 로고
    • Effect of interleukin-11 on ameliorating intestinal damage after methotrexate treatment of breast cancer in rats
    • Gibson RJ, Keefe DMK, Thompson FM, Clarke JM, Goland GJ, Cummins AG. Effect of interleukin-11 on ameliorating intestinal damage after methotrexate treatment of breast cancer in rats. Dig Dis Sci 2002;47:2751-2757
    • (2002) Dig Dis Sci , vol.47 , pp. 2751-2757
    • Gibson, R.J.1    Keefe, D.M.K.2    Thompson, F.M.3    Clarke, J.M.4    Goland, G.J.5    Cummins, A.G.6
  • 21
    • 0036387068 scopus 로고    scopus 로고
    • DNA strand-breaks induced by the topoisomerase i inhibitor camptothecin in unstimulated human white blood cells
    • Daza P, Torreblanca J, Garcia-Herdugo G, Moreno FJ. DNA strand-breaks induced by the topoisomerase I inhibitor camptothecin in unstimulated human white blood cells. Cell Biol Int 2002;26:707-713
    • (2002) Cell Biol Int , vol.26 , pp. 707-713
    • Daza, P.1    Torreblanca, J.2    Garcia-Herdugo, G.3    Moreno, F.J.4
  • 22
    • 0037179495 scopus 로고    scopus 로고
    • Detection of topoisomerase inhibitor-induced DNA strand breaks and apoptosis by the alkaline comet assay
    • Godard T, Deslandes E, Sichel F, Poul JM, Gauduchon P. Detection of topoisomerase inhibitor-induced DNA strand breaks and apoptosis by the alkaline comet assay. Mutat Res 2002;520:47-56.
    • (2002) Mutat Res , vol.520 , pp. 47-56
    • Godard, T.1    Deslandes, E.2    Sichel, F.3    Poul, J.M.4    Gauduchon, P.5
  • 23
    • 0031783728 scopus 로고    scopus 로고
    • DNA repair, cell cycle progression and cell death following Camptothecin treatment in two murine lymphoma L5178Y sublines
    • Gradzka I, Skierski J, Szumiel I. DNA repair, cell cycle progression and cell death following Camptothecin treatment in two murine lymphoma L5178Y sublines. Cell Biochem Funct 1998;16:239-252
    • (1998) Cell Biochem Funct , vol.16 , pp. 239-252
    • Gradzka, I.1    Skierski, J.2    Szumiel, I.3
  • 25
    • 0028122271 scopus 로고
    • Mutagenicity and carcinogenicity of topoisomerase-interactive agents
    • Anderson RD, Berger NA. Mutagenicity and carcinogenicity of topoisomerase-interactive agents. Mutat Res 1994;309:109-142
    • (1994) Mutat Res , vol.309 , pp. 109-142
    • Anderson, R.D.1    Berger, N.A.2
  • 26
    • 0031790615 scopus 로고    scopus 로고
    • Topoisomerase- i inhibitor SN-38 can induce DNA damage and chromosomal aberrations independent from DNA synthesis
    • Voight W, Matsui S, Yin MB, Burhans WC, Minderman H, Rustum YM. Topoisomerase- I inhibitor SN-38 can induce DNA damage and chromosomal aberrations independent from DNA synthesis. Anticancer Res 1998;18(5A):3499-3505
    • (1998) Anticancer Res , vol.18 , Issue.5 A , pp. 3499-3505
    • Voight, W.1    Matsui, S.2    Yin, M.B.3    Burhans, W.C.4    Minderman, H.5    Rustum, Y.M.6
  • 28
    • 0026625512 scopus 로고
    • The involvement of active DNA synthesis in camptothecin-induced G2 arrest: Asltered regulation of p34cdc2/cyclin B
    • Tsao YP, D'Arpa P, Liu LF. The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B. Cancer Res 1992;52:1823-1829
    • (1992) Cancer Res , vol.52 , pp. 1823-1829
    • Tsao, Y.P.1    D'Arpa, P.2    Liu, L.F.3
  • 29
    • 42749095519 scopus 로고    scopus 로고
    • Detecting genotoxic effects of potential clastogens: An in vivo study using the transgenic lacZ plasmid and the MutaTM Mouse model
    • Mahabir AG, Benthem Jv, Korsten H, Lynch AM, Bailey L, De Vries A, Hendriksen CF, Van Steeg H. Detecting genotoxic effects of potential clastogens: An in vivo study using the transgenic lacZ plasmid and the MutaTM Mouse model. Mutat Res 2008;652:151-157
    • (2008) Mutat Res , vol.652 , pp. 151-157
    • Mahabir, A.G.1    Jv, B.2    Korsten, H.3    Lynch, A.M.4    Bailey, L.5    De Vries, A.6    Hendriksen, C.F.7    Van Steeg, H.8
  • 30
    • 0026555984 scopus 로고
    • Micronuclei induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice
    • Holmstrom M, Winters V. Micronuclei induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice. Mutagenesis 1992;7:189-193
    • (1992) Mutagenesis , vol.7 , pp. 189-193
    • Holmstrom, M.1    Winters, V.2
  • 31
    • 0025049435 scopus 로고
    • Genotoxicity of inhibitors of DNA topoisomerase i (camptothecin) and II (m-ASA) in vivo and in vitro
    • Bacher LC, Allen JW, Harrington-Brock K, Campbell JA, Moore MM. Genotoxicity of inhibitors of DNA topoisomerase I (camptothecin) and II (m-ASA) in vivo and in vitro. Mutagenesis 1990;5:541-547
    • (1990) Mutagenesis , vol.5 , pp. 541-547
    • Bacher, L.C.1    Allen, J.W.2    Harrington-Brock, K.3    Campbell, J.A.4    Moore, M.M.5
  • 32
    • 0037128672 scopus 로고    scopus 로고
    • Consumption of an omege-3 fatty acids product, INCELL AAFATM, reduced side-effects of CPT-11 (irinotecan) in mice
    • Hardman WE, Moyer MP, Cameron IL. Consumption of an omege-3 fatty acids product, INCELL AAFATM, reduced side-effects of CPT-11 (irinotecan) in mice. Br J Cancer 2002;86:983-988
    • (2002) Br J Cancer , vol.86 , pp. 983-988
    • Hardman, W.E.1    Moyer, M.P.2    Cameron, I.L.3
  • 33
    • 0038734404 scopus 로고    scopus 로고
    • Genotoxicity of two anticancer drugs; Gentamicine and topotecan, in mouse bone marrow in vivo
    • Aydemir N, Bilaloglu R. Genotoxicity of two anticancer drugs; gentamicine and topotecan, in mouse bone marrow in vivo. Mutat Res 2003;537:43-51.
    • (2003) Mutat Res , vol.537 , pp. 43-51
    • Aydemir, N.1    Bilaloglu, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.