Estrogen receptor α gene promoter 0/B usage in the rat sexually dimorphic nucleus of the preoptic area

Endocrinology

Volumn 151, Issue 4, 2010, Pages 1923-1928

  Hamada, Tomohiro ^a   Sakuma, Yasuo ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; ENHANCED GREEN FLUORESCENT PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEWBORN; NONHUMAN; ORCHIECTOMY; PHENOTYPE; PREOPTIC AREA; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SEX DIFFERENTIATION; TRANSGENIC RAT;

ANIMALS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL COUNT; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; NEURONS; PREOPTIC AREA; PROMOTER REGIONS, GENETIC; RATS; RATS, TRANSGENIC; RATS, WISTAR; SEX CHARACTERISTICS;

EID: 77950207187     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1022     Document Type: Article

References (30)

1. Arnold AP, Gorski RA 1984 Gonadal steroid induction of structural sex differences in the central nervous system. Annu Rev Neurosci 7:413-442
2. Sickel MJ, McCarthy MM 2000 Calbindin-D28k immunoreactivity is a marker for a subdivision of the sexually dimorphic nucleus of the preoptic area of the rat: developmental profile and gonadal steroid modulation. J Neuroendocrinol 12:397-402
3. Gao B, Moore RY 1996 The sexually dimorphic nucleus of the hypothalamus contains GABA neurons in rat and man. Brain Res 742:163-171
4. McAbee MD, DonCarlos LL 1998 Ontogeny of region-specific sex differences in androgen receptor messenger ribonucleic acid expression in the rat forebrain. Endocrinology 139:1738-1745
5. Orikasa C, Kondo Y, Sakuma Y 2007 Transient transcription of the somatostatin gene at the time of estrogen-dependent organization of the sexually dimorphic nucleus of the rat preoptic area. Endocrinology 148:1144-1149
6. McCarthy MM, Schlenker EH, Pfaff DW 1993 Enduring consequences of neonatal treatment with antisense oligonucleotides to estrogen receptor messenger ribonucleic acid on sexual differentiation of rat brain. Endocrinology 133:433-439
7. Patchev AV, Götz F, Rohde W 2004 Differential role of estrogen receptor isoforms in sex-specific brain organization. FASEB J 18: 1568-1570
8. Kos M, Reid G, Denger S, Gannon F 2001 Genomic organization of the human ERα gene promoter region. Mol Endocrinol 15:2057-2063
9. Wilson ME, Westberry JM, Prewitt AK 2008 Dynamic regulation of estrogen receptor-α gene expression in the brain: a role for promoter methylation? Front Neuroendocrinol 29:375-385
10. Freyschuss B, Grandien K 1996 The 5́ flank of the rat estrogen receptor gene: structural characterization and evidence for tissue and species-specific promoter utilization. J Mol Endocrinol 17:197-206
11. Hirata S, Koh T, Yamada-Mouri N, Hoshi K, Kato J 1996 The untranslated first exon 'exon 0S' of the rat estrogen receptor (ER) gene. FEBS Lett 394:371-373
12. Hirata S, Koh T, Yamada-Mouri N, Kato J 1996 The novel untranslated first exon "exon 0N" of the rat estrogen receptor gene. Biochem Biophys Res Commun 225:849-854
13. Osada N, Hirata S, Shoda T, Hoshi K 2001 The novel untranslated exon "exon 0T" encoded between the exon 0 and exon 1 of the rat estrogen receptor α (ERα) gene. Endocr J 48:465-472
14. Ishii H, Kobayashi M, Sakuma Y 2010 Alternative promoter usage and alternative splicing of the rat estrogen receptor α gene generate numerous mRNA variants with distinct 5́-ends. J Steroid Biochem Mol Biol 118:59-69
15. Hamada T, Wada-Kiyama Y, Sakuma Y 2005 Visualizing fore-brain-specific usage of an estrogen receptor α promoter for receptor downregulation in the rat. Mol Brain Res 139:42-51
16. Shughrue PJ, Lane MV, Merchenthaler I 1997 Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system. J Comp Neurol 388:507-525
17. Gill RK, Christakos S 1995 Regulation by estrogen through the 5́-flanking region of the mouse calbinidin-D28k gene. Mol Endocrinol 9:319-326
18. Morris JA, Jordan CL, Breedlove SM 2004 Sexual differentiation of the vertebrate nervous system. Nature Neurosci 7:1034-1039
19. Tsukahara S 2009 Sex differences and the roles of sex steroids in apoptosis of sexually dimorphic nuclei of the preoptic area in postnatal rats. J Neuroendocrinol 21:370-376
20. Arai Y, Sekine Y, Murakami S 1996 Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats. Neurosci Res 25:403-407
21. Jacobson CD, Gorski RA 1981 Neurogenesis of the sexually dimorphic nucleus of the preoptic area in the rat. J Comp Neurol 196: 519-529
22. Tobet S, Knoll JG, Hartshorn C, Aurand E, Stratton M, Kumar P, Searcy B, McClellan K 2009 Brain sex differences and hormone influences: a moving experience? J Neuroendocrinol 21:387-392
23. Jacobson CD, Davis FC, Gorski RA 1985 Formation of the sexually dimorphic nucleus of the preoptic area: neuronal growth, migration and changes in cell number. Brain Res 353:7-18
24. Weisz J, Ward IL 1980 Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses, and neonatal offspring. Endocrinology 106:306-316
25. Swaab DF, Garcia-Falgueras A 2009 Sexual differentiation of the human brain in relation to gender identity and sexual orientation. Funct Neurol 24:17-28
26. Sakuma Y 2009 Gonadal steroid action and brain sex differentiation in the rat. J Neuroendocrinol 21:410-414
27. Houtsmuller EJ, Brand T, de Jonge FH, Joosten RN, van de Poll NE, Slob AK 1994 SDN-POA volume, sexual behavior, and partner preference of male rats affected by perinatal treatment with ATD. Physiol Behav 56:535-541
28. Garcia-Falgueras A, Swaab DF 2008 A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain 131:3132-3146
29. Comte I, Tran PB, Szele FG 2007 Techniques and strategies to analyze neural progenitor cell migration. Curr Pharm Biotechnol 8:177-185
30. Knoll JG, Wolfe CA, Tobet SA 2007 Estrogen modulates neuronal movements within the developing preoptic area- anterior hypothalamus. Eur J Neurosci 26:1097-1099