The performance of cochlin-tomoprotein detection test in the diagnosis of perilymphatic fistula

Audiology and Neurotology

Volumn 15, Issue 3, 2010, Pages 168-174

  Ikezono, Tetsuo ^a   Shindo, Susumu ^a   Sekiguchi, Satomi ^b   Morizane, Toshio ^c   Pawankar, Ruby ^a   Watanabe, Atsushi ^a   Miura, Masakazu ^d   Yagi, Toshiaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b LSI MEDIENCE CORPORATION   (Japan)

^c KANAGAWA DENTAL COLLEGE   (Japan)

^d HOKURIKU UNIVERSITY   (Japan)

Author keywords

COCH gene; Cochlin isoform; Cochlin tomoprotein; Diagnostic accuracy; Hearing loss; Human; Perilymph; Perilymphatic fistula; Sensitivity; Specificity; Vertigo

Indexed keywords

ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; FENESTRATION; FISTULA; HUMAN; IMMUNOLOGY; INNER EAR DISEASE; METABOLISM; PERILYMPH; PHYSIOLOGY; RABBIT; SECRETORY OTITIS MEDIA; SENSITIVITY AND SPECIFICITY; VESTIBULAR DISORDER;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; FENESTRATION, LABYRINTH; FISTULA; HUMANS; LABYRINTH DISEASES; OTITIS MEDIA WITH EFFUSION; PERILYMPH; RABBITS; SENSITIVITY AND SPECIFICITY; VESTIBULAR DISEASES;

EID: 77950090287     PISSN: 14203030     EISSN: 14219700     Source Type: Journal    
DOI: 10.1159/000241097     Document Type: Article

References (24)

1. Abe S, Katagiri T, Saito-Hisaminato A, Usami S, Inoue Y, Tsunoda T, Nakamura Y: Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissue. Am J Hum Genet 2003; 72: 73-82.
2. Black FO, Pesznecker S, Norton T, Fowler L, Lilly DJ, Shupert C, Hemenway WG, Peterka RJ, Jacobson ES: Surgical management of perilymphatic fistulas: a Portland experience. Am J Otol 1992; 13: 254-262.
3. Fitzgerald DC: Perilymphatic fistula and Meniere's disease: clinical series and literature review. Ann Otol Rhinol Laryngol 2001; 110: 430-436.
4. Friedland DR, Wackym PA: A critical appraisal of spontaneous perilymphatic fistulas of the inner ear. Am J Otol 1999; 20: 261-276.
5. Goodhill V: Sudden deafness and round window rupture. Laryngoscope 1971; 81: 1462-1474.
6. House JW, Morris MS, Kramer SJ, Shasky GL, Coggan BB, Putter JS: Perilymphatic fistula: surgical experience in the United States. Otolaryngol Head Neck Surg 1991; 105: 51-61.
7. Hughes GB, Sismanis A, House JW: Is there consensus in perilymph fistula management? Otolaryngol Head Neck Surg 1990; 102: 111-117.
8. Ikezono T, Omori A, Ichinose S, Pawankar R, Watanabe A, Yagi T: Identification of the protein product of the Coch gene - hereditary deafness gene - as the major component of bovine inner ear protein. Biochim Biophys Acta 2001; 3: 258-265.
9. Ikezono T, Shindo S, Ishizaki M, Li L, Tomiyama S, Takumida M, Pawankar R, Watanabe A, Saito A, Yagi T: Expression of cochlin in the vestibular organ of rats. ORL J Otorhinolaryngol Relat Spec 2005; 67: 252-258.
10. Ikezono T, Shindo S, Li L, Omori A, Ichinose S, Watanabe A, Kobayashi T, Pawankar R, Yagi T: Identification of a novel Cochlin isoform in the perilymph: insights to Cochlin function and the pathogenesis of DFNA9. Biochem Biophys Res Commun 2004; 314: 440-446.
11. Ikezono T, Shindo S, Sekiguchi S, Charuk Hanprasertpong, Li L, Pawankar R, Morizane T, Baba S, Koizumi Y, Sekine K, Watanabe A, Komatsuzaki A, Murakami S, Kobayashi T, Miura M, Yagi T: Cochlin-tomoprotein (CTP), a novel perilymph-specific protein and a potential marker for the diagnosis of perilymphatic fistula. Audiol Neurootol 2009; 14: 338-344.
12. Kohut RI, Hinojosa R, Budetti JA: Perilymphatic fistula: a histopathologic study. Ann Otol Rhinol Laryngol 1986; 95: 466-471.
13. Li L, Ikezono T, Watanabe A, Shindo S, Pawankar R, Yagi T: Expression of full-length Cochlin p63s is inner ear specific. Auris Nasus Larynx 2005; 32: 219-223.
14. Minor LB: Labyrinthine fistulae: pathobiology and management. Curr Opin Otolaryngol Head Neck Surg 2003; 11: 340-346.
15. Nomura Y: Perilymph fistula: concept, diagnosis and management. Acta Otolaryngol Suppl 1994; 514: 52-54.
16. Podoshin L, Fradis M, Ben-David J, Berger SI, Feiglin H: Perilymphatic fistula: the value of diagnostic tests. J Laryngol Otol 1994; 108: 560-563.
17. Robertson NG, Khetarpal U, Gutierrez-Espeleta GA, Bieber FR, Morton CC: Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Genomics 1994; 23: 42-50.
18. Robertson NG, Lu L, Heller S, Merchant SN, Eavey RD, McKenna M, Nadol JB, Miyamoto RT, Linthicum FH, Lubianca Neto JF, Hudspeth AJ, Seidman CE, Morton CC, Seidman JG: Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nat Genet 1998; 20: 299-303.
19. Robertson NG, Cremers CW, Huygen PL, Ikezono T, Krastins B, Kremer H, Kuo SF, Liberman MC, Merchant SN, Miller CE, Nadol JB, Sarracino DA, Verhagen WI, Morton CC: Cochlin immunostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction. Hum Mol Genet 2006; 15: 1071-1085.
20. Schuknecht HF: Myths in neurotology. Am J Otol 1992; 13: 124-126.
21. Sekine K, Ikezono T, Matsumura T, Shindo S, Watanabe A, Li L, Pawankar R, Nishino T, Yagi T: Expression of cochlin mRNA splice variants in the inner ear. Audiol Neurotol 2010;15:88-96.
22. Shindo S, Ikezono T, Ishizaki M, Sekiguchi S, Mizuta K, Li L, Takumida M, Pawankar R, Yagi T: Spatiotemporal expression of Cochlin in the inner ear of rats during postnatal development. Neurosci Lett 2008; 444: 148-152.
23. Wall C, Rauch SD: Perilymph fistula pathophysiology. Otolaryngol Head Neck Surg 1995; 112: 145-153.
24. Weber PC, Bluestone CD, Perez B: Outcome of hearing and vertigo after surgery for congenital perilymphatic fistula in children. Am J Otolaryngol 2003; 24: 138-142. 5