Spectacular modification of Gambogic acid on microwave irradiation in methanol: Isolation and structure identification of two products with potent anti-tumor activity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2438-2442

  Wang, Xiaojian ^a   Lu, Na ^a   Yang, Qian ^a   Dai, Qinsheng ^a   Tao, Lei ^a   Guo, Xiaoke ^a   Guo, Qinglong ^a   You, Qidong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anti tumor effect; Apoptosis; Gambogic acid; Microwave

Indexed keywords

4 OXATRICYCLO[4.3.1.0 3,7]DEC 2 ONE DERIVATIVE; BRIDGED COMPOUND; GAMBOGIC ACID; GAMBOGIC ACID DERIVATIVE; METHANOL; UNCLASSIFIED DRUG;

ACIDITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CYCLIZATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MICROWAVE IRRADIATION; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; METHANOL; MICROSCOPY, FLUORESCENCE; MICROWAVES; MODELS, MOLECULAR; XANTHONES;

GARCINIA;

EID: 77950063194     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.021     Document Type: Article

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