Identification of potent, highly constrained CGRP receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2572-2576

  Stump, Craig A ^a   Bell, Ian M ^a   Bednar, Rodney A ^a   Fay, John F ^a   Gallicchio, Steven N ^a   Hershey, James C ^a   Jelley, Richard ^a   Kreatsoulas, Constantine ^a   Moore, Eric L ^a   Mosser, Scott D ^a   Quigley, Amy G ^a   Roller, Shane A ^a   Salvatore, Christopher A ^a   Sharik, Steven S ^a   Theberge, Cory R ^a   Zartman, C Blair ^a   Kane, Stefanie A ^a   Graham, Samuel L ^a   Selnick, Harold G ^a   Vacca, Joseph P ^a   Williams, Theresa M ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Calcitonin gene related peptide; CGRP; Migraine

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; QUINOLINE;

ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG CONFORMATION; DRUG HALF LIFE; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN;

ANIMALS; BIOLOGICAL AVAILABILITY; DOGS; DRUG EVALUATION, PRECLINICAL; MACACA MULATTA; QUINOLINES; RATS; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE;

EID: 77950034065     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.086     Document Type: Article

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