What has functional neuroimaging done for primary headache ... and for the clinical neurologist?

Journal of Clinical Neuroscience

Volumn 17, Issue 5, 2010, Pages 547-553

  Sprenger, Till ^a   Goadsby, Peter J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cluster headache; Functional MRI; Functional neuroimaging; Migraine; Positron emission tomography; Tension type headache

Indexed keywords

CLUSTER HEADACHE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEADACHE; HUMAN; MIGRAINE; MIGRAINE AURA; MORPHOMETRICS; NEUROIMAGING; PAROXYSMAL HEMICRANIA; PATHOGENESIS; PATHOPHYSIOLOGY; PATIENT EDUCATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW; TENSION HEADACHE; TRIGEMINAL AUTONOMIC CEPHALALGIA;

BRAIN; BRAIN MAPPING; HEADACHE; HEADACHE DISORDERS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY;

EID: 77949914898     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2009.09.030     Document Type: Review

References (98)

1. Bergerot A., Holland P.R., Akerman S., et al. Animal models of migraine: looking at the component parts of a complex disorder. Eur J Neurosci 24 (2006) 1517-1534
2. Goadsby P.J., Lipton R.B., and Ferrari M.D. Migraine-current understanding and treatment. N Engl J Med 346 (2002) 257-270
3. Afridi S.K., and Goadsby P.J. Neuroimaging of migraine. Curr Pain Headache Rep 10 (2006) 221-224
4. Sprenger T., Ruether K.V., Boecker H., et al. Altered metabolism in frontal brain circuits in cluster headache. Cephalalgia 27 (2007) 1033-1042
5. Fumal A., Laureys S., Di Clemente L., et al. Orbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraine. Brain 129 (2006) 543-550
6. Sprenger T., Willoch F., Miederer M., et al. Opioidergic changes in the pineal gland and hypothalamus in cluster headache: a ligand PET study. Neurology 66 (2006) 1108-1110
7. Sprenger T., Henriksen G., Valet M., et al. Positron emission tomography in pain research. From the structure to the activity of the opiate receptor system. Schmerz 21 (2007) 503-513
8. Sprenger T., Berthele A., Platzer S., et al. What to learn from in vivo opioidergic brain imaging?. Eur J Pain 9 (2005) 117-121
9. Jueptner M., and Weiller C. Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI. Neuroimage 2 (1995) 148-156
10. Lodi R., Pierangeli G., Tonon C., et al. Study of hypothalamic metabolism in cluster headache by proton MR spectroscopy. Neurology 66 (2006) 1264-1266
11. Wang S.J., Lirng J.F., Fuh J.L., et al. Reduction in hypothalamic 1H-MRS metabolite ratios in patients with cluster headache. J Neurol Neurosurg Psychiatry 77 (2006) 622-625
12. May A., and Matharu M. New insights into migraine: application of functional and structural imaging. Curr Opin Neurol 20 (2007) 306-309
13. Matharu M., and May A. Functional and structural neuroimaging in trigeminal autonomic cephalalgias. Curr Pain Headache Rep 12 (2008) 132-137
14. Peyron R., Laurent B., and Garcia-Larrea L. Functional imaging of brain responses to pain. A review and meta-analysis. Neurophysiol Clin 30 (2000) 263-288
15. Valet M., Sprenger T., Boecker H., et al. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain-an fMRI analysis. Pain 109 (2004) 399-408
16. May A., Kaube H., Buchel C., et al. Experimental cranial pain elicited by capsaicin: a PET study. Pain 74 (1998) 61-66
17. May A., Bahra A., Buchel C., et al. Hypothalamic activation in cluster headache attacks. Lancet 352 (1998) 275-278
18. Afridi S.K., Giffin N.J., Kaube H., et al. A positron emission tomographic study in spontaneous migraine. Arch Neurol 62 (2005) 1270-1275
19. Weiller C., May A., Limmroth V., et al. Brain stem activation in spontaneous human migraine attacks. Nat Med 1 (1995) 658-660
20. Afridi S.K., Matharu M.S., Lee L., et al. A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. Brain 128 (2005) 932-939
21. Sprenger T., Valet M., Boecker H., et al. Opioidergic activation in the medial pain system after heat pain. Pain 122 (2006) 63-67
22. Zubieta J.K., Smith Y.R., Bueller J.A., et al. Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science 293 (2001) 311-315
23. Goadsby P.J., and Lipton R.B. A review of paroxysmal hemicranias, SUNCT syndrome and other short-lasting headaches with autonomic feature, including new cases. Brain 120 Pt 1 (1997) 193-209
24. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition Cephalalgia 2004;24(Suppl. 1):9-160.
25. Sprenger T., Boecker H., Tolle T.R., et al. Specific hypothalamic activation during a spontaneous cluster headache attack. Neurology 62 (2004) 516-517
26. Goadsby P.J. Pathophysiology of cluster headache: a trigeminal autonomic cephalgia. Lancet Neurol 1 (2002) 251-257
27. May A., Ashburner J., Buchel C., et al. Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat Med 5 (1999) 836-838
28. Leone M., Franzini A., and Bussone G. Stereotactic stimulation of posterior hypothalamic gray matter in a patient with intractable cluster headache. N Engl J Med 345 (2001) 1428-1429
29. Leone M., Proietti Cecchini A., Franzini A., et al. Lessons from 8 years' experience of hypothalamic stimulation in cluster headache. Cephalalgia 28 (2008) 787-797 [discussion 798]
30. May A., Leone M., Boecker H., et al. Hypothalamic deep brain stimulation in positron emission tomography. J Neurosci 26 (2006) 3589-3593
31. Barrett T., Kent S., and Voudouris N. Does melatonin modulate beta-endorphin, corticosterone, and pain threshold?. Life Sci 66 (2000) 467-476
32. May A., Bahra A., Buchel C., et al. Functional magnetic resonance imaging in spontaneous attacks of SUNCT: short-lasting neuralgiform headache with conjunctival injection and tearing. Ann Neurol 46 (1999) 791-794
33. Matharu M.S., Cohen A.S., Frackowiak R.S., et al. Posterior hypothalamic activation in paroxysmal hemicrania. Ann Neurol 59 (2006) 535-545
34. Peatfield R., Bahra A., and Goadsby P.J. Trigeminal-autonomic cephalgias (TACs). Cephalalgia 18 (1998) 358
35. Afridi S., Kaube H., and Goadsby P.J. Occipital activation in glyceryl trinitrate induced migraine with visual aura. J Neurol Neurosurg Psychiatry 76 (2005) 1158-1160
36. Denuelle M., Fabre N., Payoux P., et al. Hypothalamic activation in spontaneous migraine attacks. Headache 47 (2007) 1418-1426
37. Bahra A., Matharu M.S., Buchel C., et al. Brainstem activation specific to migraine headache. Lancet 357 (2001) 1016-1017
38. Matharu M.S., Bartsch T., Ward N., et al. Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study. Brain 127 (2004) 220-230
39. Raskin N.H., Hosobuchi Y., and Lamb S. Headache may arise from perturbation of brain. Headache 27 (1987) 416-420
40. Veloso F., Kumar K., and Toth C. Headache secondary to deep brain implantation. Headache 38 (1998) 507-515
41. Haas D.C., Kent P.F., and Friedman D.I. Headache caused by a single lesion of multiple sclerosis in the periaqueductal gray area. Headache 33 (1993) 452-455
42. Goadsby P.J. Neurovascular headache and a midbrain vascular malformation-evidence for a role of the brainstem in chronic migraine. Cephalalgia 22 (2002) 107-111
43. Rocca M.A., Ceccarelli A., Falini A., et al. Brain gray matter changes in migraine patients with T2-visible lesions: a 3-T MRI study. Stroke 37 (2006) 1765-1770
44. Welch K.M., Nagesh V., Aurora S.K., et al. Periaqueductal gray matter dysfunction in migraine: cause or the burden of illness?. Headache 41 (2001) 629-637
45. Valfre W., Rainero I., Bergui M., et al. Voxel-based morphometry reveals gray matter abnormalities in migraine. Headache 48 (2008) 109-117
46. Kim J.H., Suh S.I., Seol H.Y., et al. Regional grey matter changes in patients with migraine: a voxel-based morphometry study. Cephalalgia 28 (2008) 598-604
47. Lashley K. Patterns of cerebral integration indicated by the scotomas of migraine. Arch Neurol Psychiat 46 (1941) 331-339
48. Leão A.A.P. Spreading depression of activity in the cerebral cortex. J Neurophysiol 7 (1944) 359-390
49. Fabricius M., Fuhr S., Bhatia R., et al. Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 129 (2006) 778-790
50. Strong A.J., Fabricius M., Boutelle M.G., et al. Spreading and synchronous depressions of cortical activity in acutely injured human brain. Stroke 33 (2002) 2738-2743
51. Mayevsky A., Doron A., Manor T., et al. Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res 740 (1996) 268-274
52. Olesen J., Larsen B., and Lauritzen M. Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine. Ann Neurol 9 (1981) 344-352
53. Sanchez del Rio M., Bakker D., Wu O., et al. Perfusion weighted imaging during migraine: spontaneous visual aura and headache. Cephalalgia 19 (1999) 701-707
54. Cao Y., Welch K.M., Aurora S., et al. Functional MRI-BOLD of visually triggered headache in patients with migraine. Arch Neurol 56 (1999) 548-554
55. Hadjikhani N., Sanchez Del Rio M., Wu O., et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 98 (2001) 4687-4692
56. Granziera C., DaSilva A.F., Snyder J., et al. Anatomical alterations of the visual motion processing network in migraine with and without aura. PLoS Med 3 (2006) e402
57. Woods R.P., Iacoboni M., and Mazziotta J.C. Brief report: bilateral spreading cerebral hypoperfusion during spontaneous migraine headache. N Engl J Med 331 (1994) 1689-1692
58. Denuelle M., Fabre N., Payoux P., et al. Posterior cerebral hypoperfusion in migraine without aura. Cephalalgia 28 (2008) 856-862
59. Coghill R.C., Sang C.N., Berman K.F., et al. Global cerebral blood flow decreases during pain. J Cereb Blood Flow Metab 18 (1998) 141-147
60. Lance J.W., Lambert G.A., Goadsby P.J., et al. Brainstem influences on the cephalic circulation: experimental data from cat and monkey of relevance to the mechanism of migraine. Headache 23 (1983) 258-265
61. Goadsby P.J., and Duckworth J.W. Low frequency stimulation of the locus coeruleus reduces regional cerebral blood flow in the spinalized cat. Brain Res 476 (1989) 71-77
62. Cao Y., Aurora S.K., Nagesh V., et al. Functional MRI-BOLD of brainstem structures during visually triggered migraine. Neurology 59 (2002) 72-78
63. Schmidt-Wilcke T., Leinisch E., Straube A., et al. Gray matter decrease in patients with chronic tension type headache. Neurology 65 (2005) 1483-1486
64. Kuchinad A., Schweinhardt P., Seminowicz D.A., et al. Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?. J Neurosci 27 (2007) 4004-4007
65. Valet M., Gundel H., Sprenger T., et al. Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study. Psychosom Med 71 (2009) 49-56
66. May A. Chronic pain may change the structure of the brain. Pain 137 (2008) 7-15
67. Teutsch S., Herken W., Bingel U., et al. Changes in brain gray matter due to repetitive painful stimulation. Neuroimage 42 (2008) 845-849
68. Palmieri A., Mainardi F., Maggioni F., et al. Cluster-like headache secondary to cavernous sinus metastasis. Cephalalgia 25 (2005) 743-745
69. Moskowitz M.A. Cluster headache: evidence for a pathophysiologic focus in the superior pericarotid cavernous sinus plexus. Headache 28 (1988) 584-586
70. Schuh-Hofer S., Richter M., Israel H., et al. The use of radiolabelled human serum albumin and SPECT/MRI co-registration to study inflammation in the cavernous sinus of cluster headache patients. Cephalalgia 26 (2006) 1115-1122
71. Sianard-Gainko J., Milet J., Ghuysen V., et al. Increased parasellar activity on gallium SPECT is not specific for active cluster headache. Cephalalgia 14 (1994) 132-133
72. Sprenger T., Valet M., Hammes M., et al. Hypothalamic activation in trigeminal autonomic cephalgia: functional imaging of an atypical case. Cephalalgia 24 (2004) 753-757
73. Goadsby P.J., Matharu M.S., and Boes C.J. SUNCT syndrome or trigeminal neuralgia with lacrimation. Cephalalgia 21 (2001) 82-83
74. Gardella L., Viruega A., Rojas H., et al. A case of a patient with SUNCT syndrome treated with Jannetta procedure. Cephalalgia 21 (2001) 996-999
75. Black D.F., and Dodick D.W. Two cases of medically and surgically intractable SUNCT: a reason for caution and an argument for a central mechanism. Cephalalgia 22 (2002) 201-204
76. Cohen A.S., Matharu M.S., and Goadsby P.J. Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) or cranial autonomic features (SUNA)-a prospective clinical study of SUNCT and SUNA. Brain 129 (2006) 2746-2760
77. Cohen A.S., Matharu M.S., and Goadsby P.J. Suggested guidelines for treating SUNCT and SUNA. Cephalalgia 25 (2005) 1200
78. 18F-MPPF-PET study. Cephalalgia 28 (2008) 1282-1291
79. de Tommaso M., Valeriani M., Guido M., et al. Abnormal brain processing of cutaneous pain in patients with chronic migraine. Pain 101 (2003) 25-32
80. de Tommaso M., Libro G., Guido M., et al. Habituation of single CO2 laser-evoked responses during interictal phase of migraine. J Headache Pain 6 (2005) 195-198
81. Afra J., Proietti Cecchini A., Sandor P.S., et al. Comparison of visual and auditory evoked cortical potentials in migraine patients between attacks. Clin Neurophysiol 111 (2000) 1124-1129
82. Valeriani M., de Tommaso M., Restuccia D., et al. Reduced habituation to experimental pain in migraine patients: a CO(2) laser evoked potential study. Pain 105 (2003) 57-64
83. Kropp P., and Gerber W.D. Is increased amplitude of contingent negative variation in migraine due to cortical hyperactivity or to reduced habituation?. Cephalalgia 13 (1993) 37-41
84. Kropp P., and Gerber W.D. Contingent negative variation-findings and perspectives in migraine. Cephalalgia 13 (1993) 33-36
85. Nappi G., Sandrini G., Alfonsi E., et al. Impaired circadian rhythmicity of nociceptive reflex threshold in cluster headache. Headache 42 (2002) 125-131
86. Kruit M.C., van Buchem M.A., Hofman P.A., et al. Migraine as a risk factor for subclinical brain lesions. JAMA 291 (2004) 427-434
87. Rozen T.D. Vanishing cerebellar infarcts in a migraine patient. Cephalalgia 27 (2007) 557-560
88. Joutel A., Corpechot C., Ducros A., et al. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 383 (1996) 707-710
89. Richards A., van den Maagdenberg A.M., Jen J.C., et al. C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy. Nat Genet 39 (2007) 1068-1070
90. Dowson A., Mullen M.J., Peatfield R., et al. Migraine Intervention With STARFlex Technology (MIST) trial: a prospective, multicenter, double-blind, sham-controlled trial to evaluate the effectiveness of patent foramen ovale closure with STARFlex septal repair implant to resolve refractory migraine headache. Circulation 117 (2008) 1397-1404
91. Apkarian A.V., Bushnell M.C., Treede R.D., et al. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 9 (2005) 463-484
92. Goadsby P.J. The migrainous brain: what you see is not all you get?. PLoS Med 3 (2006) e404
93. Kloppel S., Stonnington C.M., Chu C., et al. Automatic classification of MR scans in Alzheimer's disease. Brain 131 (2008) 681-689
94. Leone M., May A., Franzini A., et al. Deep brain stimulation for intractable chronic cluster headache: proposals for patient selection. Cephalalgia 24 (2004) 934-937
95. Saper J., Goadsby P.J., Silberstein S., et al. Occipital nerve stimulation (ONS) for treatment of intractable chronic migraine (ICM): 3-month results from the ONSTIM feasibility study. Neurology 72 (2009) A252
96. Burns B., Watkins L., and Goadsby P.J. Treatment of medically intractable cluster headache by occipital nerve stimulation: long-term follow-up of eight patients. Lancet 369 (2007) 1099-1106
97. 18F]AM5144 and related pyrazole compounds. Nucl Med Biol 32 (2005) 361-366
98. Rstad E., Platzer S., Berthele A., et al. Towards NR2B receptor selective imaging agents for PET-synthesis and evaluation of N-[11C]-(2-methoxy)benzyl (E)-styrene-, 2-naphthyl- and 4-trifluoromethoxyphenylamidine. Bioorg Med Chem 14 (2006) 6307-6313