Herb-drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats

Chemico-Biological Interactions

Volumn 184, Issue 3, 2010, Pages 458-465

  Chien, Chao Feng ^a   Wu, Yu Tse ^a   Lee, Wen Chuan ^a   Lin, Lie Chwen ^b   Tsai, Tung Hu ^a,c,d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Andrographis paniculata; Andrographolide; Herb drug interaction; Microdialysis; Pharmacokinetics

Indexed keywords

14 DEOXY 11,12 DIDEHYDROANDROGRAPHISIDE; 14 DEOXY 11,12 DIHYDROANDROGRAPHISIDE; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; ANDROPANOSIDE; NEOANDROGRAPHOLIDE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE COMPARISON; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG STRUCTURE; HERB DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MICRODIALYSIS; NONHUMAN; RAT;

ANDROGRAPHIS; ANIMALS; AREA UNDER CURVE; CYTOCHROME P-450 CYP1A2; DITERPENES; HALF-LIFE; HERB-DRUG INTERACTIONS; MALE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; THEOPHYLLINE;

ANDROGRAPHIS PANICULATA; RATTUS;

EID: 77949914516     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.01.017     Document Type: Article

References (37)

1. Eisenberg D.M., Davis R.B., Ettner S.L., Appel S., Wilkey S., Van Rompay M., Kessler R.C. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. J. Am. Med. Assoc. 1998, 280:1569-1575.
2. Ernst E. Harmless herbs? A review of the recent literature. Am. J. Med. 1998, 104:170-178.
3. World Health Organization, WHO Monographs on Selected Medicinal Plants Volume 2, World Health Organization, Geneva, Switzerland, 2002, pp. 12-24.
4. Hovhannisyan A.S., Abrahamyan H., Gabrielyan E.S., Panossian A.G. The effect of Kan Jang extract on the pharmacokinetics and pharmacodynamics of warfarin in rats. Phytomedicine 2006, 13:318-323.
5. Jain D.C., Gupta M.M., Saxena S., Kumar S. LC analysis of hepatoprotective diterpenoids from Andrographis paniculata. J. Pharm. Biomed. Anal. 2000, 22:705-709.
6. Shen Y.C., Chen C.F., Chiou W.F. Andrographolide prevents oxygen radical production by human neutrophils:possible mechanism(s) involved in its anti-inflammatory effect. Br. J. Pharmacol. 2002, 135:399-406.
7. Kumar R.A., Sridevi K., Kumar N.V., Nanduri S., Rajagopal S. Anticancer and immunostimulatory compounds from Andrographis paniculata. J. Ethnopharmacol. 2004, 92:291-295.
8. Thisoda P., Rangkadilok N., Pholphana N., Worasuttayangkurn L., Ruchirawat S., Satayavivad J. Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation. Eur. J. Pharmacol. 2006, 553:39-45.
9. Calabrese C., Berman S.H., Babish J.G., Ma X., Shinto L., Dorr M., Wells K., Wenner C.A., Standish L.J. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother. Res. 2000, 14:333-338.
10. Singha P.K., Roy S., Dey S. Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice. J. Ethnopharmacol. 2007, 111:13-21.
11. Jaruchotikamol A., Jarukamjorn K., Sirisangtrakul W., Sakuma T., Kawasaki Y., Nemoto N. Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes. Toxicol. Appl. Pharmacol. 2007, 224:156-162.
12. Pekthong D., Blanchard N., Abadie C., Bonet A., Heyd B., Mantion G., Berthelot A., Richert L., Martin H. Effects of Andrographis paniculata extract and andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures. Chem. Biol. Interact. 2009, 179:247-255.
13. Pekthong D., Martin H., Abadie C., Bonet A., Heyd B., Mantion G., Richert L. Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide. J. Ethnopharmacol. 2008, 115:432-440.
14. Bao Z., Guan S., Cheng C., Wu S., Wong S.H., Kemeny D.M., Leung B.P., Wong W.S. A novel anti-inflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kappa B pathway. Am. J. Respir. Crit. Care Med. 2009, 179:657-665.
15. Blanc P.D., Trupin L., Earnest G., Katz P.P., Yelin E.H., Eisner M.D. Alternative therapies among adults with a reported diagnosis of asthma or rhinosinusitis: data from a population-based survey. Chest 2001, 120:1461-1467.
16. Shannon M. Life-threatening events after theophylline overdose: a 10-year prospective analysis. Arch. Intern. Med. 1999, 159:989-994.
17. Ogilvie R.I. Clinical pharmacokinetics of theophylline. Clin. Pharmacokinet. 1978, 3:267-293.
18. Jan W.C., Lin L.C., Chen C.F., Tsai T.H. Herb-drug interaction of Evodia rutaecarpa extract on the pharmacokinetics of theophylline in rats. J. Ethnopharmacol. 2005, 102:440-445.
19. Fujita T., Fujitani R., Takeda Y., Takaishi Y., Yamada T., Kido M., Miura I. On the diterpenoids of Andrographis paniculata: X-ray crystallographic analysis of andrographolide and structure determination of new minor diterpenoids. Chem. Phar. Bull. 1984, 32:2117-2125.
20. Tsai T.H. Pharmacokinetics of pefloxacin and its interaction with cyclosporine A, a P-glycoprtein modulator, in rat blood, brain and bile, using simultaneous microdialysis,. Br. J. Pharmacol. 2001, 132:1310-1316.
21. Stahle L., Arner P., Ungerstedt U. Drug distribution studies with microdialysis. III. Extracellular concentration of caffeine in adipose tissue in man. Life Sci. 1991, 49:1853-1858.
22. U.S. Department of Health and Human Services Guidelines, Bioanalytical Method Validation, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM), May 2001.
23. Tsai T.H., Liu M.C. Determination of unbound theophylline in rat blood and brain by microdialysis and liquid chromatography. J. Chromatogr. A 2004, 1032:97-101.
24. Tang J., Sun J., Zhang Y., Li L., Cui F., He Z. Herb-drug interactions: effect of Ginkgo biloba extract on the pharmacokinetics of theophylline in rats. Food Chem. Toxicol. 2007, 45:2441-2445.
25. Yamaoka K., Nakagawa T., Uno T. Application of Akaike's Information Criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm. 1978, 6:165-175.
26. Tsai T.H. Assaying protein unbound drugs using microdialysis techniques. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2003, 797:161-173.
27. Ueng Y.F., Ko H.C., Chen C.F., Wang J.J., Chen K.T. The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug Metab. Dispos. 2002, 30:349-353.
28. Ueng Y.F., Ko H.C., Chen C.F., Wang J.J., Chen K.T. Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice. Life Sci. 2002, 71:1267-1277.
29. Izzo A.A., Ernst E. Interactions between herbal medicines and prescribed drugs: a systematic review. Drugs 2001, 61:2163-2175.
30. Shargel L., Yu A. Hepatic elimination of drugs. Applied Biopharmceutics and Pharmacokinetics 1999, 353-397. Appleton and Lange, London, UK. fourth edition. C.L. Mehalik (Ed.).
31. Shargel L., Yu A. Nonlinear pharmacokinetics. Applied Biopharmceutics and Pharmacokinetics 1999, 449-474. Appleton and Lange, London, UK. fourth edition. C.L. Mehalik (Ed.).
32. Teunissen M.W., Brorens I.O., Geerlings J.M., Breimer D.D. Dose-dependent elimination of theophylline in rats. Xenobiotica 1985, 15:165-171.
33. Shimada T., Yamazaki H., Mimura M., Inui Y., Guengerich F.P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 1994, 270:414-423.
34. Faber M.S., Jetter A., Fuhr U. Assessment of CYP1A2 activity in clinical practice: why, how, and when?. Basic Clin. Pharmacol. Toxicol. 2005, 97:125-134.
35. Kojima J., Katoh H., Taniguchi T., Kawai H., Fukui H., Ohnishi A., Onodera K. Usefulness and safety of theophylline injection form (Theodrip) for the treatment of acute asthma. Methods Find. Exp. Clin. Pharmacol. 2000, 22:247-252.
36. Ohnishi A., Kato M., Kojima J., Ushiama H., Yoneko M., Kawai H. Differential pharmacokinetics of theophylline in elderly patients. Drugs Aging 2003, 20:71-84.
37. Thamlikitkul V., Dechatiwongse T., Theerapong S., Chantrakul C., Boonroj P., Punkrut W., Ekpalakorn W., Boontaeng N., Taechaiya S., Petcharoen S. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J. Med. Assoc. Thai. 1991, 74:437-442.