Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling

Circulation

Volumn 117, Issue 1, 2008, Pages 61-69

  Tang, Tong ^a,c   Gao, Mei Hua ^a,c   Lai, N Chin ^a,c   Firth, Amy L ^a   Takahashi, Toshiyuki ^a   Guo, Tracy ^a   Yuan, Jason X J ^a   Roth, David M ^b,c   Hammond, H Kirk ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b University of California   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Calcium; Heart contractility; Knockout mice; Receptors, adrenergic, beta

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE TYPE 6; BETA ADRENERGIC RECEPTOR; CALCIUM; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLAMBAN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ADENYLATE CYCLASE TYPE 6 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE; GENE DELETION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSGENIC MOUSE;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CYCLIC AMP; DIASTOLE; GENE DELETION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RECEPTORS, ADRENERGIC, BETA; VENTRICULAR DYSFUNCTION, LEFT;

EID: 37349042536     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.730069     Document Type: Article

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