A new norlupane triterpene from the leaves of Acanthopanax koreanum increases the differentiation of osteoblastic MC3T3-e1 cells

Archives of Pharmacal Research

Volumn 33, Issue 1, 2010, Pages 75-80

  Park, Sang Hyouk ^a   Nhiem, Nguyen Xuan ^a,b   Kiem, Phan Van ^b   Choi, Eun Mi ^a   Kim, Jeong Ah ^a   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Viet Nam)

Author keywords

3 ,11 dihydroxy 20,23 dioxo 30 norlupane 28 oic acid; Acanthopanax koreanum; Araliaceae; Lupane triterpene

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 ALPHA,11 ALPHA DIHYDROXY 23 OXO LUP 20 (29) EN 28 OIC ACID; 3 ALPHA,11 ALPHA DIHYDROXYLUP 20 (29) EN 28 OIC ACID; ACANTHOPANAX KOREANUM EXTRACT; ALKALINE PHOSPHATASE; BETULABUSIDE B; COLLAGEN; ENT KAUR 16 EN 19 OIC ACID; HERBACEOUS AGENT; METHANOL; NORLUPANE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ACANTHOPANAX; ACANTHOPANAX KOREANUM; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PLANT LEAF;

3T3 CELLS; ACANTHOPANAX; ALKALINE PHOSPHATASE; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; ESTRADIOL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OSTEOBLASTS; PLANT EXTRACTS; PLANT LEAVES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TRITERPENES;

EID: 77949881569     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-2228-4     Document Type: Article

References (23)

1. D. L. Alekel A. S. Germain C. T. Peterson K. B. Hanson J. W. Stewart T. Toda 2000 Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women Am. J. Clin. Nutr. 72 844 852 1:CAS:528:DC%2BD3cXmsFGrt7Y%3D 10966908
2. A. Brzezinski A. Debi 1999 Phytoestrogens: the 'natural' selective estrogen receptor modulators? Eur. J. Obstet. Gynecol. Reprod. Biol. 85 47 51 10.1016/S0301-2115(98)00281-4 1:CAS:528:DyaK1MXjt1KksLw%3D 10428321 (Pubitemid 29248782)
3. I. Calis A. Yuruker H. Ruegger A. Wright O. Sticher 1993 Anatolioside E: A new acyclic monoterpene glycoside from Viburnum orientale Helv. Chim. Acta 76 2563 2569 10.1002/hlca.19930760716 1:CAS:528:DyaK2cXht12nu7k%3D
4. X. F. Cai G. H. Shen N. T. Dat O. H. Kang Y. M. Lee J. J. Lee Y. H. Kim 2003 Inhibitory effect of kaurane type diterpenoids from Acanthopanax koreanum on TNF-α secretion from trypsin-stimulated HMC-1 cells Arch. Pharm. Res. 26 731 734 10.1007/BF02976683 1:CAS:528:DC%2BD3sXotFKksbY%3D 14560922
5. X. F. Cai I. S. Lee G. Shen N. T. Dat J. J. Lee Y. H. Kim 2004 Triterpenoids from Acanthopanax koreanum root and their inhibitory activities on NFAT transcription Arch Pharm. Res. 27 825 828 10.1007/BF02980173 1:CAS:528:DC%2BD2cXnslCntrc%3D 15460442
6. S. Y. Chang C. S. Yook T. Nohara 1999 Lupane-triterpene glycosides from leaves of Acanthopanax koreanum Phytochemistry 50 1369 1374 10.1016/S0031- 9422(98)00402-6 1:CAS:528:DyaK1MXjtFChtbc%3D (Pubitemid 29204919)
7. A. A. El-Gamal 2008 Cytotoxic lupane-, secolupane-, and oleananetype triterpenes from Viburnum awabuki Nat. Prod. Res. 22 191 197 10.1080/14786410701761019 1:CAS:528:DC%2BD1cXktlWhsLo%3D 18266145
8. S. B. Han S. K. Park H. J. Ahn Y. D. Yoon Y. H. Kim J. J. Lee K. H. Lee J. S. Moon H. C. Kim H. M. Kim 2003 Characterization of B cell membrane receptors of polysaccharide isolated from the root of Acanthopanax koreanum Int. Immunopharmacol. 3 683 691 10.1016/S1567-5769(03)00056-0 1:CAS:528: DC%2BD3sXjvFWgu74%3D 12757737 (Pubitemid 36577295)
9. P. V. Kiem N. T. Dat C. V. Minh J. J. Lee Y. H. Kim 2003 Lupane-triterpenes from the leaves of Brassaiopsis glomerulata Arch. Pharm. Res. 26 594 596 10.1007/BF02976706 1:CAS:528:DC%2BD3sXnt1Wgsbc%3D 12967192
10. J. Y. Kim K. S. Yang 2003 Screening of antioxidant activity of Acanthopanax species in vitro Yakhak Hoeji 47 361 364 1:CAS:528: DC%2BD2MXptlKmsw%3D%3D
11. X. Q. Liu S. Y. Chang S. Y. Park T. Nohara C. S. Yook 2002 A new lupane-triterpene glycoside from the leaves of Acanthopanax gracilistylus Arch. Pharm. Res. 25 831 836 10.1007/BF02977000 1:CAS:528:DC%2BD3sXht1amsA%3D%3D 12510834
12. S. Mohan S. Kutilek C. Zhang H. G. Shen Y. Kodama A. K. Srivastava J. E. Wergedal W. G. Bermer D. J. Baylink 2000 Comparison of bone formation responses to parathyroid hormone (1-34), (1-31), and (2-34) in mice Bone 27 471 478 10.1016/S8756-3282(00)00355-0 1:CAS:528:DC%2BD3cXnt1Sjtrs%3D 11033441
13. M. K. Na W. K. Oh Y. H. Kim X. F. Cai S. H. Kim B. Y. Kim J. S. Ahn 2006 Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum Bioorg. Med. Chem. Lett. 16 3061 3064 10.1016/j.bmcl.2006. 02.053 1:CAS:528:DC%2BD28XjvFygtbY%3D 16545563
14. J. X. Nan X. X. Jin H. H. Lian X. F. Cai Y. Z. Jian H. R. Jin J. J. Lee 2008 A diterpenoid acanthoic acid from Acanthopanax koreanum protects against D- galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice Biol. Pharm. Bull. 31 738 742 10.1248/bpb.31.738 1:CAS:528:DC%2BD1cXmtlarsLw%3D 18379074
15. I. Persson E. Weiderpass L. Bergkvist R. Bergstrom C. Schairer 1999 Ricks of breast and endometrial cancer after estrogen and estrogen-progestin replacement Cancer Causes Control 10 253 260 10.1023/A:1008909128110 1:STN:280:DyaK1MvhtVajuw%3D%3D 10482483 (Pubitemid 29358958)
16. B. L. Riggs L. J. Melton III 1992 The prevention and treatment of osteoporosis N. Engl. J. Med. 327 620 627 1:CAS:528:DyaK3sXnt12jsg%3D%3D 1640955
17. G. D. Roodman 1996 Advances in bone biology: the osteoblast Endocrinol. Rev. 17 308 332 1:CAS:528:DyaK28Xltl2mtrY%3D
18. K. H. Shin S. Lee 2002 The chemistry of secondary products from Acanthopanax species and their pharmacological activities Nat. Prod. Sci. 8 111 126 1:CAS:528:DC%2BD3sXnvFKgtg%3D%3D
19. H. Sudo H. Kodama Y. Amagi S. Yamamoto S. Kasai 1983 In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria J. Cell Biol. 96 191 198 10.1083/jcb.96.1.191 1:CAS:528:DyaL3sXmvFKmtA%3D%3D 6826647
20. D. M. Tham C. D. Gardner W. L. Haskell 1998 Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence Eur. J. Clin. Nutr. 52 850 855 10.1038/sj.ejcn.1600659
21. H. Tullberg-Reinert G. Jundt 1999 In situ measurement of collagen synthesis by human bone cells with a Sirius Redbased colorimetric microassay: effects of transforming growth factor β2 and ascorbic acid 2-phosphate Histochem. Cell Biol. 112 271 276 10.1007/s004180050447 1:CAS:528: DyaK1MXms1CqtL8%3D 10550611 (Pubitemid 29515494)
22. P. D. Ty M. Lischewski H. V. Phiet A. Preiss P. V. Nguyen G. Adam 1985 3α,11α-Dihydroxy-23-oxo-lup-20(29)-en-28-oic acid from Acanthopanax trifoliatus Phytochemistry 24 867 869 10.1016/S0031-9422(00)84914-6 1:CAS:528:DyaL2MXktlCrtbo%3D
23. Yook, C. S., "Coloured Medicinal Plants of Korean". Academy Publishing Co., Ltd, Seoul, Korea, pp. 371, (1993).