The comparison of the effects of anesthetic doses of ketamine, propofol, and etomidate on ischemia-reperfusion injury in skeletal muscle

Fundamental and Clinical Pharmacology

Volumn 24, Issue 2, 2010, Pages 215-222

  Ergün, Yusuf ^a   Darendeli, Sacide ^a   Imrek, Seçil ^a   Kilinç, Metin ^a   Öksüz, Hafize ^a  

^a KAHRAMANMARAS SUTCU IMAM UNIVERSITY   (Turkey)

Author keywords

Etomidate; Ischemia reperfusion injury; Ketamine; Propofol; Skeletal muscle

Indexed keywords

CATALASE; COPPER; ETOMIDATE; GLUTATHIONE PEROXIDASE; IRON; KETAMINE; LIPURO; MALONALDEHYDE; PENTAL SODYUM; PROPOFOL; SELENIUM; SUPEROXIDE DISMUTASE; THIOPENTAL; UNCLASSIFIED DRUG; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CELL PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; FEMALE; LIPID PEROXIDATION; MUSCLE INJURY; MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SHAM PROCEDURE; SKELETAL MUSCLE; WISTAR RAT;

ANESTHETICS, DISSOCIATIVE; ANESTHETICS, INTRAVENOUS; ANIMALS; DISEASE MODELS, ANIMAL; ETOMIDATE; FEMALE; KETAMINE; MUSCLE, SKELETAL; PROPOFOL; RATS; RATS, WISTAR; REPERFUSION INJURY; THIOPENTAL; ZINC;

EID: 77949881244     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2009.00748.x     Document Type: Article

References (44)

1. Kato R., Foex P. Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Can. J. Anesth. (2002) 49 777 791.
2. Kevin L.G., Novalija E., Stowe D.F. Reactive oxygen species as mediators of cardiac injury and protection: The relevance to anesthesia practice. Anesth. Analg. (2005) 101 1275 1287.
3. Chang M.L., Yang J., Kem S. et al. Nicotinamide and Ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion. Neurosci. Lett. (2002) 322 137 140.
4. Fukuda S., Murakawa T., Takeshita H., Toda N. Direct effects of ketamine on isolated canine cerebral and mesenteric arteries. Anesth. Analg. (1983) 62 553 558.
5. Salman A.E., Dal D., Salman M.A., Iskit A.B., Aypar U. The effect of ketamine on acute musculer ischemia reperfusion injury in rats. Eur. J. Anesthesiol. (2005) 22 712 716.
6. Kahraman S., Kilinç K., Dal D., Erdem K. Propofol attenuates formation of lipid peroxidases in tourniquet induced ischemia-reperfusion injury. Br. J. Anesth. (1997) 78 279 281.
7. Aldemir O., çelebi H., çevik C., Duzgun E. The effects of propofol or halothane on free radical production after tourniquet induced ischeia-reperfusion injury during knee arthroplasty. Acta Anesthesiol. Scan. (2001) 45 1221 1225.
8. Mitchell R.N., Cotran R.S., Cellular pathology I: Cell injury and cell death, in : Cotran R.S., Kumar V., Robbins S.L. (Eds Robbins-pathologic basis of disease, 5th edn, W.B. Saunders Company, Philadelphia, 1994, pp. 1 34.
9. Atahan E., Ergün Y., Kurutaş E.B., çetinus E., Ergün U.G. Ischemia-reperfusion injury in rat skeletal muscle is attenuated by zinc aspartate. J. Surg. Res. (2007) 137 109 116.
10. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. (1979) 95 351 358.
11. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. (1951) 193 265 275.
12. Fridovich I. The biology of oxygen radicals. Science (1978) 201 875 880.
13. Beutler E. Catalase, in : Beutler E. Ed Red cell metabolism, Grune and Stratton Company, New York, 1975, pp. 89 90.
14. Awasthi Y.C., Beutler E., Srivastava S.K. Purification and properties of human erythrocyte glutathione peroxidase. J. Biol. Chem. (1975) 250 5144 5149.
15. Ogawa T., Mimura Y. Antioxidant effect of zinc on acute renal failure induced by ischemia-reperfusion injury in rats. Am. J. Nephrol. (1999) 19 609 614.
16. Fridovich I. Superoxide dismutases. Adv. Enzymol. Relat. Areas Mol. Biol. (1974) 41 35 97.
17. Alva N., Palomeque J., Carbonell T. Nitric oxide induced by ketamine/xylazine anestesia maintains hepatic blood flow during hypothermia. Nitric Oxide (2006) 15 64 69.
18. Ferdinandy P., Schultz R. Nitric oxide, superoxide, and peroxynitrite in myocardial Ischeamia-reperfusion injury and preconditioning. Br. J. Pharmacol. (2003) 138 532 543.
19. Khanna A., Cowled P.A., Fitridge R.A. Nitric oxide and skeletal muscle reperfusion injury: current controversies (research review). J. Surg. Res. (2005) 128 98 107.
20. Moro M.A., Darley-Usmar V.M., Goodwin D.A. et al. Paradoxical fate and biological action of peroxynitrite on human platelets. Proc. Natl Acad. Sci. USA (1994) 91 6702 6706.
21. Hogg N., Singh R.J., Kalyanaraman B. The role of glutathione in the transport and catabolism of nitric oxide. FEBS Lett. (1996) 382 223 228.
22. Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide: Physiology, pathophysiolopy, and pharmacology. Pharmacol. Rev. (1991) 43 109 142.
23. Hemler K.S., Suliburk J.W., Mercer D.W. Ketamine Induced gastroprotection during endotoxemia: Role of heme-oxygenase-1. Dig. Dis. Sci. (2006) 51 1571 1581.
24. Barker J.E., Knight K.R., Romeo R., Hurley J.V., Morrison W.A., Stewart A.G. Targeted disruption of the nitric oxide synthase 2 gene protects against ischaemia/reperfusion injury to skeletal muscle. J. Pathol. (2001) 194 109 115.
25. Zhang L., Looney C.G., Qi W.-N. et al. Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase. J. Appl. Physiol. (2003) 94 1473 1478.
26. Runzer T.D., Ansley D.M., Godin D.V., Chambers G.K. Tissue antioxidant capacity during anesthesia: Propofol enhances in vivo red cell and tissue antioxidant capacity in a rat model. Anesth. Analg. (2002) 94 89 93.
27. Mouithys-Mickalad A., Hans P., Deby-Dupont G. et al. Propofol reacts with peroxynitrite to form a phenoxyl radical: demonstration by electron spin resonans. Biochem. Biophys. Res. Commun. (1998) 249 833 837.
28. De La Cruz J.P., Sedeno G., Carmona A., Sánchez de la Cuesta F. The in vitro effects of propofol on tissular oxidative stress in the rat. Anesth. Analg. (1998) 87 1141 1146.
29. Ansley D.M., Lee J., Godin D.V., Garnett M.E., Qayumi A.K. Propofol enhances red cell antioxidant capacity in swine and humans. Can. J. Anaesth. (1998) 45 233 239.
30. Mathy-Hartert M., Deby-Dupont G., Hans P., Deby C., Lamy M. Protective activity of propofol, diprivan, and intralipid against active oxygen species. Mediators Inflamm. (1998) 7 327 333.
31. Yaǧmurdur H., Ayyildiz A., Karaguzel E. The preventive effects of thiopental and propofol on testicular ischemia-reperfusion injury. Acta. Anaesthesiol. Scan. (2006) 50 1238 1243.
32. Kaplan N., Yaǧmurdur N., Kilinç K. The protective effects of intravenous anesthetics and verapamil in gut ischemia/reperfusion-induced liver injury. Anesth. Analg. (2007) 105 1371 1378.
33. Hao Q., Maret W. Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease. J. Alzheimers. Dis. (2005) 8 161 170.
34. Song Y., Wang J., Li X.K., Cai L. Zinc and the diabetic heart. Biometals (2005) 18 325 332.
35. Herbein G., Varin A., Fulop T. NF-kappaB, AP-1, Zinc-deficiency and aging. Biogerontology (2006) 7 409 419.
36. Wintergerst E.S., Maggini S., Hornig D.H. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann. Nutr. Metab. (2006) 50 85 94.
37. Hennig B., Toborek M., Mcclain C.J. Antiatherogenic properties of zinc: implications in endothelial cell metabolism. Nutrition (1996) 12 711 717.
38. Beattie J.H., Kwun I.S. Is zinc deficiency a risk factor for atherosclerosis. Br. J. Nutr. (2004) 91 177 181.
39. Özkan K.U., Boran ç., Kilinç M. The effect of zinc Aspartate pretreatment on ischemia-reperfusion injury and early changes of blood and tissue antioxidant enzyme activities after unilateral testicular torsion-detorsion. J. Pediatr. Surg. (2004) 39 91 95.
40. Ozdemir G., Inanc F. Zinc may protect remote ocular injury caused by intestinal ischemia reperfusion in rats. Tohoku. J. Exp. Med. (2005) 206 247 251.
41. DiSilvestro R.A. Zinc in relation to diabetes and oxidative disease. J. Nutr. (2000) 130 1509S 1511S.
42. Powell S.R. The antioxidant properties of zinc. J. Nutr. (2000) 130 1447S 1511S.
43. Bray T.M., Bettger W.J. The physiological role of zinc as an antioxidant. Free Radic. Biol. Med. (1990) 8 281 291.
44. Kim S.Y., Kwak J.S., Shin J.P., Lee S.H. The protection of the retina from ischemic injury by the free radical scavenger EGb 761 and zinc in the cat retina. Ophthalmologica (1998) 212 268 274.