Effect of Counter-Ions and Penetration Enhancers on the Skin Permeation of Flurbiprofen

Journal of Pharmaceutical Sciences

Volumn 99, Issue 4, 2010, Pages 1826-1837

  Ma, Xu ^a   Fang, Liang ^a   Gu, Jianpeng ^b   Zhao, Nanxi ^a   He, Zhonggui ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b YANBIAN UNIVERSITY   (China)

Author keywords

Flurbiprofen; HPLC; In vitro; Ion pairing; Organic amine; Penetration enhancer; Percutaneous absorption; Solubility; Transdermal

Indexed keywords

1 METHYL 2 PYRROLIDINONE; ALCOHOL; COUNTERION; DIETHANOLAMINE; DIETHYLAMINE; ETHANOLAMINE; FLURBIPROFEN; LAUROCAPRAM; MENTHOL; MYRISTIC ACID ISOPROPYL ESTER; N (2' HYDROXYETHANOL)PIPERDINE; OLEIC ACID; PENETRATION ENHANCING AGENT; PROPYLENE GLYCOL; SORBITAN OLEATE; TRIETHANOLAMINE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG STRUCTURE; LIPOPHILICITY; MALE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; SKIN ABSORPTION; SKIN PERMEABILITY; SOLUBILIZATION;

EID: 77949840267     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21953     Document Type: Article

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