Nanophase ceramics for improved drug delivery: Current opportunities and challenges

American Ceramic Society Bulletin

Volumn 89, Issue 2, 2010, Pages 24-32

  Yang, Lei ^a   Sheldon, Brian W ^a   Webster, Thomas J ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77949763557     PISSN: 00027812     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (44)

1. Webster TJ. Nanophase ceramics as improved bone tissue engineering materials. American Ceramic Society Bulletin 2003;82:23-28.
2. Goldberg M, Langer R and Jia X. Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polymer Edn 2007; 18: 241-68.
3. Quan CY, Chang C, Wei H, Chen CS, Xu XD, Cheng SX, et al. Dual targeting of a thermosensitive nanogel conjugated with transferrin and RGD-containing peptide for effective cell uptake and drug release. Nanotechnology 2009; 20: 335101.
4. Biondi M, Ungaro F, Qualia F, et al. Controlled drug delivery in tissue engineering. Adv Drug Deliv Rev 2008; 60: 229-42.
5. Ginebra MP , Traykova T and Planell JA. Calcium phosphate cements as bone drug delivery systems: A review. Journal of Controlled Release 2006;113: 102-110.
6. Kim K and Fisher JP. Nanoparticle technology in bone tissue engineering. Journal of Drug Targeting 2007; 15: 241-52.
7. Liu TY, Chen SY, Liu DM, Liou SC. On the study of BSA-loaded calcium-deficient hydroxyapatite nano-carriers for controlled drug delivery. Journal of Controlled Release 2005;107: 112-121.
8. Melville AJ, Rodriguez-Lorenzo LM, Forsythe JS. Effects of calcination temperature on the drug delivery behaviour of Ibuprofen from hydroxyapatite powders. J Mater Sci: Mater Med 2008; 19:1187-1195.
9. Victor SP, Kumar TTS. Tailoring calcium-deficient hydroxyapatite nanocarriers for enhanced release of antibiotics. Journal of Biomedical Nanotechnology 2008; 4: 203-209.
10. Cai Y, Pan H, Xu X, et al. Ultrasonic controlled morphology transformation of hollow calcium phosphate nanospheres: A smart and biocompatible drug release system. Chem. Mater 2007: 19; 3081-3083.
11. Cai Y, Tang R. Calcium phosphate nanoparticles in biomineralization and biomaterials. J Mater Chem 2008; 18: 3775-3787.
12. Wang J, Gao X, Yang X, Gan Y, Weng W, Gou Z. A Facile Strategy for In situ core-template-functionalizingsiliceous hollow nanospheres for guest species entrapment. Nanoscale Res Lett 2009; 4:1171-1177.
13. Chen JF, Ding HM, Wang JX, Shao L. Preparation and characterization of porous hollow silica nanoparticles for drug delivery application. Biomaterials 2004; 25: 723-727.
14. Ma H, Tarr J, DeCoster MA, McNamara J, Caruntu D, Chen JF, O'Connor JG and Zhou WL. Synthesis of magnetic porous hollow silica nanotubes for drug delivery. Journal of Applied Physics 2009; 105: 07B309.
15. Wang Y and Tseng WJ. A novel technique for synthesizing nanoshell hollow alumina particles. J. Am. Ceram. Soc. 2009; 92 [S1]:S32-S37.
16. Cai A, Xu X, Pan H, Tao J, Liu R, Tang R, and Cho K. Direct synthesis of hollow vaterite nanospheres from amorphous calcium carbonate nanoparticles via phase transformation. J. Phys. Chem. C 2008; 112: 11324-11330.
17. Majewski P and Thierry B. Functionalized magnetite nanoparticles- synthesis, properties, and bio-applications. Critical Reviews in Solid State and Materials Sciences 2007; 32: 203-215.
18. Zhao M, Beauregard DA, Loizou L, Davletov B and Brindle KM. Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nature Med. 2001; 7: 1241-1244.
19. Shubayev VI, Pisanic TR, Jin S. Magnetic nanoparticles for theragnostics. Advanced Drug Delivery Reviews 2009; 61: 467-477.
20. Balasundaram G, Webster TJ. Applications of magnetic nanoparticles for the treatment of osteoporosis. Mater. Res. Soc. Symp. Proc. 2007; 1019: 1019-FF02-06.
21. Pareta RA, Taylor E, Webster TJ. Increased osteoblast density in the presence of novel calcium phosphate coated magnetic nanoparticles. Nanotechnology 2008; 19: 265101.
22. Berry CC, Curtis ASG. Functionalisation of magnetic nanoparticles for applications in biomedicine. J Phys D: Appl Phys 2003; 36: R198-206.
23. Xu C and Sun S. Monodisperse magnetic nanoparticles for biomedical applications. Polym Int 2007; 56: 821-6.
24. Bechet D, Couleaud P, Frochot C, Viriot ML, Guillemin F, Barberi-Heyob M. Nanoparticles as vehicles for delivery of photodynamic therapy agents. Trends in Biotechnology 2008; 26: 612-621.
25. Roy I, Ohulchanskyy TY, Pudavar HE, Bergey EJ, Oseroff AR, et al. Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy. J. Am. Chem. Soc. 2003; 125: 7860-7865.
26. Choi SJ, Oh JM, Choy JH. Biocompatible ceramic nanocarrier for drug delivery with high efficiency. Journal of the Ceramic Society of Japan 2009; 117:543-549.
27. Kriven WM, Kwak SY, Wallig MA, Choy JH. Bio-resorbable nanoceramics for gene and drug delivery. MRS Bulletin 2004; 29: 33-37.
28. Kim KH, Kwon TY, Kim SY, et al. Preparation and characterization of anodized titanium surfaces and their effect on osteoblast responses. J Oral Implantol 2006;32: 8-13.
29. Yao C, Webster TJ. Anodization: A promising nano-modification technique of titanium implants for orthopedic applications. J Nanoscience and Nanotechnology 2006; 6: 2682-92.
30. Yao C, Webster TJ. Prolonged antibiotic delivery from anodized nanotubular titanium using a co-precipitation drug loading method. J Biomed Mater Res Part B: Appl Biomater 2009; 91B: 587-595.
31. Popat KC, Eltgroth M, LaTempa TJ, et al. Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes. Biomaterials 2007; 28: 4880-4888.
32. 2 nanotubes functionalized with regions of bone morphogenetic protein-2 increases osteoblast adhesion. J Biomed Mater Res A 2007; 84A: 447-453.
33. Xu HHK, Weir MD, Simon CG. Injectable and strong nanoapatite scaffolds for cell/growth factor delivery and bone regeneration. Dental Materials 2008; 24:1212-222.
34. Teller M, Gopp U, Neumann HG, Kuhn KD. Release of gentamicin from bone regenerative materials: An in vitro study. J Biomed Mater Res Part B: Appl Biomater 2007; 81B: 23-29.
35. Ottania V, Martinia D, Franchia M, Ruggeria A, Raspantib M. Hierarchical structures in fibrillar collagens. Micron 2002; 33: 587-596.
36. Prabhakaran MP, Venugopal J, Ramakrishna R. Electrospun nanostructured scaffolds for bone tissue engineering. Acta Biomaterialia 2009; 5: 2884-2893.
37. Dai XS, Shivkumar S. Hybrid analogs for the production of porous calcium phosphate scaffolds. Materials Science and Engineering C-Biomimetic and Supramolecular Systems 2008; 28: 336-340.
38. Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles. Small 2008; 4: 26-49.
39. Nawroth T, Rusp M, May RP. Magnetic liposomes and entrapping: time-resolved neutron scattering TR-SANS and electron microscopy. Physica B: Condensed Matter 2004; 350: E635- E638.
40. Liu TY, Hu SH, Liu DM, et al. Biomedical nanoparticle carriers with combined thermal and magnetic responses. Nano Today 2009; 4: 52-65.
41. Sahoo SK, Labhasetwar V. Nanotech approaches to drug delivery and imaging. Drug Discovery Today 2003; 8: 1112-1120.
42. Shen H, Tan J, Saltzman WM. Surface-mediated gene transfer from nanocomposites of controlled texture. Nat Mater. 2004; 3:569-574.
43. Bae C, Yoo H, Kim S, Lee K, Kim J, Sung MM, et al. Templatedirected synthesis of oxide nanotubes: Fabrication, characterization, and applications. Chem. Mater. 2008; 20: 756-767.
44. Vitale-Brovarone C Baino F, Miola M, Mortera R, Onida B, Verne E. Glass-ceramic scaffolds containing silica mesophases for bone grafting and drug delivery. J Mater Sci: Mater Med 2009; 20:809-820.