The octarepeat region of the prion protein is conformationally altered in PrPSc

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Yam, Alice Y ^a   Gao, Carol Man ^a   Wang, Xuemei ^a   Wu, Ping ^a,b   Peretz, David ^a,c  

^a Novartis Vaccines and Diagnostics Inc   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; OCTAPEPTIDE; PRION PROTEIN; TRYPSIN; OLIGOPEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; CONFORMATIONAL TRANSITION; CREUTZFELDT JAKOB DISEASE; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; IMMUNODETECTION; PROTEIN CONFORMATION; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR WEIGHT; PROTEIN FOLDING; WESTERN BLOTTING;

BLOTTING, WESTERN; CREUTZFELDT-JAKOB SYNDROME; EPITOPES; HUMANS; MOLECULAR WEIGHT; OLIGOPEPTIDES; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS; PRPSC PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; TRYPSIN;

EID: 77949757691     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009316     Document Type: Article

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