메뉴 건너뛰기




Volumn 192, Issue 7, 2010, Pages 1890-1901

Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistance

Author keywords

[No Author keywords available]

Indexed keywords

DNA; METRONIDAZOLE; NITROREDUCTASE; OXIDOREDUCTASE; RDXA NITROREDUCTASE; RDXB NITROREDUCTASE; UNCLASSIFIED DRUG;

EID: 77949697432     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01638-09     Document Type: Article
Times cited : (10)

References (58)
  • 2
    • 40749084835 scopus 로고    scopus 로고
    • Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry
    • Bingham-Ramos, L. K., and D. R. Hendrixson. 2008. Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry. Infect. Immun. 76:1105-1114.
    • (2008) Infect. Immun , vol.76 , pp. 1105-1114
    • Bingham-Ramos, L.K.1    Hendrixson, D.R.2
  • 4
    • 33645823370 scopus 로고    scopus 로고
    • Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food - 10 States, United States, 2005
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. 2006. Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food - 10 States, United States, 2005. MMWR Morb. Mortal. Wkly. Rep. 55:392-395.
    • (2006) MMWR Morb. Mortal. Wkly. Rep , vol.55 , pp. 392-395
  • 6
    • 33645218215 scopus 로고    scopus 로고
    • The Helicobacter pylori chemotaxis receptor TlpB (HP0103) is required for pH taxis and for colonization of the gastric mucosa
    • Croxen, M. A., G. Sisson, R. Melano, and P. S. Hoffman. 2006. The Helicobacter pylori chemotaxis receptor TlpB (HP0103) is required for pH taxis and for colonization of the gastric mucosa. J. Bacteriol. 188:2656-2665.
    • (2006) J. Bacteriol , vol.188 , pp. 2656-2665
    • Croxen, M.A.1    Sisson, G.2    Melano, R.3    Hoffman, P.S.4
  • 8
    • 0032530155 scopus 로고    scopus 로고
    • A phylogenomic study of the MutS family of proteins
    • Eisen, J. A. 1998. A phylogenomic study of the MutS family of proteins. Nucleic Acids Res. 26:4291-4300.
    • (1998) Nucleic Acids Res , vol.26 , pp. 4291-4300
    • Eisen, J.A.1
  • 11
    • 0031953727 scopus 로고    scopus 로고
    • Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase
    • Goodwin, A., D. Kersulyte, G. Sisson, S. J. Veldhuyzen van Zanten, D. E. Berg, and P. S. Hoffman. 1998. Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase. Mol. Microbiol. 28:383-393.
    • (1998) Mol. Microbiol , vol.28 , pp. 383-393
    • Goodwin, A.1    Kersulyte, D.2    Sisson, G.3    Veldhuyzen van Zanten, S.J.4    Berg, D.E.5    Hoffman, P.S.6
  • 12
    • 0039425207 scopus 로고    scopus 로고
    • Stability of related human and chicken Campylobacter jejuni genotypes after passage through chick intestine studied by pulsed-field gel electrophoresis
    • Hanninen, M. L., M. Hakkinen, and H. Rautelin. 1999. Stability of related human and chicken Campylobacter jejuni genotypes after passage through chick intestine studied by pulsed-field gel electrophoresis. Appl. Environ. Microbiol. 65:2272-2275.
    • (1999) Appl. Environ. Microbiol , vol.65 , pp. 2272-2275
    • Hanninen, M.L.1    Hakkinen, M.2    Rautelin, H.3
  • 13
    • 55949128309 scopus 로고    scopus 로고
    • Antimicrobial drug resistance as determined by the E-test in Campylobacter jejuni, C. coli, and C. lari isolates from the ceca of broiler and layer chickens in Grenada
    • Hariharan, H., S. Sharma, A. Chikweto, V. Matthew, and C. DeAllie. 2009. Antimicrobial drug resistance as determined by the E-test in Campylobacter jejuni, C. coli, and C. lari isolates from the ceca of broiler and layer chickens in Grenada. Comp. Immunol. Microbiol. Infect. Dis. 32:21-28.
    • (2009) Comp. Immunol. Microbiol. Infect. Dis , vol.32 , pp. 21-28
    • Hariharan, H.1    Sharma, S.2    Chikweto, A.3    Matthew, V.4    DeAllie, C.5
  • 14
    • 0018391487 scopus 로고
    • Arylsulfatase in Salmonella typhimurium: Detection and influence of carbon source and tyramine on its synthesis
    • Henderson, M. J., and F. H. Milazzo. 1979. Arylsulfatase in Salmonella typhimurium: detection and influence of carbon source and tyramine on its synthesis. J. Bacteriol. 139:80-87.
    • (1979) J. Bacteriol , vol.139 , pp. 80-87
    • Henderson, M.J.1    Milazzo, F.H.2
  • 15
    • 33748503644 scopus 로고    scopus 로고
    • A phase-variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism
    • Hendrixson, D. R. 2006. A phase-variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism. Mol. Microbiol. 61:1646-1659.
    • (2006) Mol. Microbiol , vol.61 , pp. 1646-1659
    • Hendrixson, D.R.1
  • 16
    • 52649180089 scopus 로고    scopus 로고
    • Restoration of flagellar biosynthesis by varied mutational events in Campylobacter jejuni
    • Hendrixson, D. R. 2008. Restoration of flagellar biosynthesis by varied mutational events in Campylobacter jejuni. Mol. Microbiol. 70:519-536.
    • (2008) Mol. Microbiol , vol.70 , pp. 519-536
    • Hendrixson, D.R.1
  • 17
    • 0035050923 scopus 로고    scopus 로고
    • Transposon mutagenesis of Campylobacter jejuni identifies a bipartite energy taxis system required for motility
    • Hendrixson, D. R., B. J. Akerley, and V. J. DiRita. 2001. Transposon mutagenesis of Campylobacter jejuni identifies a bipartite energy taxis system required for motility. Mol. Microbiol. 40:214-224.
    • (2001) Mol. Microbiol , vol.40 , pp. 214-224
    • Hendrixson, D.R.1    Akerley, B.J.2    DiRita, V.J.3
  • 18
    • 1942532926 scopus 로고    scopus 로고
    • Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract
    • Hendrixson, D. R., and V. J. DiRita. 2004. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Mol. Microbiol. 52:471-484.
    • (2004) Mol. Microbiol , vol.52 , pp. 471-484
    • Hendrixson, D.R.1    DiRita, V.J.2
  • 19
    • 0142125272 scopus 로고    scopus 로고
    • 28-dependent flagellar genes in Campylobacter jejuni is associated with formation of the flagellar secretory apparatus
    • 28-dependent flagellar genes in Campylobacter jejuni is associated with formation of the flagellar secretory apparatus. Mol. Microbiol. 50:687-702.
    • (2003) Mol. Microbiol , vol.50 , pp. 687-702
    • Hendrixson, D.R.1    DiRita, V.J.2
  • 20
    • 34247576793 scopus 로고    scopus 로고
    • Characterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis
    • Iwaki, H., T. Muraki, S. Ishihara, Y. Hasegawa, K. N. Rankin, T. Sulea, J. Boyd, and P. C. Lau. 2007. Characterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis. J. Bacteriol. 189:3502-3514.
    • (2007) J. Bacteriol , vol.189 , pp. 3502-3514
    • Iwaki, H.1    Muraki, T.2    Ishihara, S.3    Hasegawa, Y.4    Rankin, K.N.5    Sulea, T.6    Boyd, J.7    Lau, P.C.8
  • 21
    • 62549150494 scopus 로고    scopus 로고
    • Guillain-Barre syndrome and Campylobacter infection
    • I. Nachamkin, C. M. Szymanski, and M. J. Blaser ed, 3rd ed. ASM Press, Washington, DC
    • Jacobs, B. C., A. Van Belkum, and H. P. Endtz. 2008. Guillain-Barre syndrome and Campylobacter infection, p. 245-262. In I. Nachamkin, C. M. Szymanski, and M. J. Blaser (ed.), Campylobacter, 3rd ed. ASM Press, Washington, DC.
    • (2008) Campylobacter , pp. 245-262
    • Jacobs, B.C.1    Van Belkum, A.2    Endtz, H.P.3
  • 22
    • 0033054099 scopus 로고    scopus 로고
    • The role of the rdxA gene in the evolution of metronidazole resistance in Helicobacter pylori
    • Jenks, P. J., R. L. Ferrero, and A. Labigne. 1999. The role of the rdxA gene in the evolution of metronidazole resistance in Helicobacter pylori. J. Antimicrob. Chemother. 43:753-758.
    • (1999) J. Antimicrob. Chemother , vol.43 , pp. 753-758
    • Jenks, P.J.1    Ferrero, R.L.2    Labigne, A.3
  • 23
    • 0034879759 scopus 로고    scopus 로고
    • Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole
    • Jeong, J. Y., A. K. Mukhopadhyay, J. K. Akada, D. Dailidiene, P. S. Hoffman, and D. E. Berg. 2001. Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole. J. Bacteriol. 183:5155-5162.
    • (2001) J. Bacteriol , vol.183 , pp. 5155-5162
    • Jeong, J.Y.1    Mukhopadhyay, A.K.2    Akada, J.K.3    Dailidiene, D.4    Hoffman, P.S.5    Berg, D.E.6
  • 24
    • 0033811410 scopus 로고    scopus 로고
    • Jeong, J. Y., A. K. Mukhopadhyay, D. Dailidiene, Y. Wang, B. Velapatino, R. H. Gilman, A. J. Parkinson, G. B. Nair, B. C. Wong, S. K. Lam, R. Mistry, I. Segal, Y. Yuan, H. Gao, T. Alarcon, M. L. Brea, Y. Ito, D. Kersulyte, H. K. Lee, Y. Gong, A. Goodwin, P. S. Hoffman, and D. E. Berg. 2000. Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori. J. Bacteriol. 182:5082-5090.
    • Jeong, J. Y., A. K. Mukhopadhyay, D. Dailidiene, Y. Wang, B. Velapatino, R. H. Gilman, A. J. Parkinson, G. B. Nair, B. C. Wong, S. K. Lam, R. Mistry, I. Segal, Y. Yuan, H. Gao, T. Alarcon, M. L. Brea, Y. Ito, D. Kersulyte, H. K. Lee, Y. Gong, A. Goodwin, P. S. Hoffman, and D. E. Berg. 2000. Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori. J. Bacteriol. 182:5082-5090.
  • 25
    • 65249160474 scopus 로고    scopus 로고
    • Activation of the Campylobacter jejuni FlgSR two-component system is linked to the flagellar export apparatus
    • Joslin, S. N., and D. R. Hendrixson. 2009. Activation of the Campylobacter jejuni FlgSR two-component system is linked to the flagellar export apparatus. J. Bacteriol. 191:2656-2667.
    • (2009) J. Bacteriol , vol.191 , pp. 2656-2667
    • Joslin, S.N.1    Hendrixson, D.R.2
  • 26
    • 41549108063 scopus 로고    scopus 로고
    • Analysis of the Campylobacter jejuni FlgR response regulator suggests integration of diverse mechanisms to activate an NtrC-like protein
    • Joslin, S. N., and D. R. Hendrixson. 2008. Analysis of the Campylobacter jejuni FlgR response regulator suggests integration of diverse mechanisms to activate an NtrC-like protein. J. Bacteriol. 190:2422-2433.
    • (2008) J. Bacteriol , vol.190 , pp. 2422-2433
    • Joslin, S.N.1    Hendrixson, D.R.2
  • 27
    • 0027234856 scopus 로고
    • Identification, synthesis and properties of 5-(aziridin-1-yl)-2-nitro-4-nitrosobenzamide, a novel DNA crosslinking agent derived from CB1954
    • Knox, R. J., F. Friedlos, P. J. Biggs, W. D. Flitter, M. Gaskell, P. Goddard, L. Davies, and M. Jarman. 1993. Identification, synthesis and properties of 5-(aziridin-1-yl)-2-nitro-4-nitrosobenzamide, a novel DNA crosslinking agent derived from CB1954. Biochem. Pharmacol. 46:797-803.
    • (1993) Biochem. Pharmacol , vol.46 , pp. 797-803
    • Knox, R.J.1    Friedlos, F.2    Biggs, P.J.3    Flitter, W.D.4    Gaskell, M.5    Goddard, P.6    Davies, L.7    Jarman, M.8
  • 28
    • 0021824456 scopus 로고
    • A point-source outbreak of campylobacteriosis associated with consumption of raw milk
    • Korlath, J. A., M. T. Osterholm, L. A. Judy, J. C. Forfang, and R. A. Robinson. 1985. A point-source outbreak of campylobacteriosis associated with consumption of raw milk. J. Infect. Dis. 152:592-596.
    • (1985) J. Infect. Dis , vol.152 , pp. 592-596
    • Korlath, J.A.1    Osterholm, M.T.2    Judy, L.A.3    Forfang, J.C.4    Robinson, R.A.5
  • 30
    • 0033727511 scopus 로고    scopus 로고
    • Frameshift mutations in rdxA and metronidazole resistance in North American Helicobacter pylori isolates
    • Kwon, D. H., J. A. Pena, M. S. Osato, J. G. Fox, D. Y. Graham, and J. Versalovic. 2000. Frameshift mutations in rdxA and metronidazole resistance in North American Helicobacter pylori isolates. J. Antimicrob. Chemother. 46:793-796.
    • (2000) J. Antimicrob. Chemother , vol.46 , pp. 793-796
    • Kwon, D.H.1    Pena, J.A.2    Osato, M.S.3    Fox, J.G.4    Graham, D.Y.5    Versalovic, J.6
  • 31
    • 0028180756 scopus 로고
    • Vibrio harveyi NADPH-flavin oxidoreductase: Cloning, sequencing and overexpression of the gene and purification and characterization of the cloned enzyme
    • Lei, B., M. Liu, S. Huang, and S. C. Tu. 1994. Vibrio harveyi NADPH-flavin oxidoreductase: cloning, sequencing and overexpression of the gene and purification and characterization of the cloned enzyme. J. Bacteriol. 176:3552-3558.
    • (1994) J. Bacteriol , vol.176 , pp. 3552-3558
    • Lei, B.1    Liu, M.2    Huang, S.3    Tu, S.C.4
  • 32
    • 0033616612 scopus 로고    scopus 로고
    • Nitroreductase A is regulated as a member of the soxRS regulon of Escherichia coli
    • Liochev, S. I., A. Hausladen, and I. Fridovich. 1999. Nitroreductase A is regulated as a member of the soxRS regulon of Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 96:3537-3539.
    • (1999) Proc. Natl. Acad. Sci. U. S. A , vol.96 , pp. 3537-3539
    • Liochev, S.I.1    Hausladen, A.2    Fridovich, I.3
  • 33
    • 15544364461 scopus 로고    scopus 로고
    • Colonization and inflammation deficiencies in Mongolian gerbils infected by Helicobacter pylori chemotaxis mutants
    • McGee, D. J., M. L. Langford, E. L. Watson, J. E. Carter, Y. T. Chen, and K. M. Ottemann. 2005. Colonization and inflammation deficiencies in Mongolian gerbils infected by Helicobacter pylori chemotaxis mutants. Infect. Immun. 73:1820-1827.
    • (2005) Infect. Immun , vol.73 , pp. 1820-1827
    • McGee, D.J.1    Langford, M.L.2    Watson, E.L.3    Carter, J.E.4    Chen, Y.T.5    Ottemann, K.M.6
  • 34
    • 77949714533 scopus 로고    scopus 로고
    • Burden of illness of Campylobacteriosis and sequelae
    • I. Nachamkin, C. M. Szymanski, and M. J. Blaser ed, 3rd ed. ASM Press, Washington, DC
    • Molbak, K., and A. Havelaar. 2008. Burden of illness of Campylobacteriosis and sequelae, p. 151-162. In I. Nachamkin, C. M. Szymanski, and M. J. Blaser (ed.), Campylobacter, 3rd ed. ASM Press, Washington, DC.
    • (2008) Campylobacter , pp. 151-162
    • Molbak, K.1    Havelaar, A.2
  • 35
    • 1242318677 scopus 로고    scopus 로고
    • Transcriptome and proteome analysis of Bacillus subtilis gene expression in response to superoxide and peroxide stress
    • Mostertz, J., C. Scharf, M. Hecker, and G. Homuth. 2004. Transcriptome and proteome analysis of Bacillus subtilis gene expression in response to superoxide and peroxide stress. Microbiology 150:497-512.
    • (2004) Microbiology , vol.150 , pp. 497-512
    • Mostertz, J.1    Scharf, C.2    Hecker, M.3    Homuth, G.4
  • 36
    • 0034445698 scopus 로고    scopus 로고
    • DNA rearrangements in the flagellin locus of an flaA mutant of Campylobacter jejuni during colonization of chicken ceca
    • Nuijten, P. J., A. J. van den Berg, I. Formentini, B. A. van der Zeijst, and A. A. Jacobs. 2000. DNA rearrangements in the flagellin locus of an flaA mutant of Campylobacter jejuni during colonization of chicken ceca. Infect. Immun. 68:7137-7140.
    • (2000) Infect. Immun , vol.68 , pp. 7137-7140
    • Nuijten, P.J.1    van den Berg, A.J.2    Formentini, I.3    van der Zeijst, B.A.4    Jacobs, A.A.5
  • 37
    • 66249136829 scopus 로고    scopus 로고
    • Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori
    • Olekhnovich, I. N., A. Goodwin, and P. S. Hoffman. 2009. Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori. FEBS J. 276:3354-3364.
    • (2009) FEBS J , vol.276 , pp. 3354-3364
    • Olekhnovich, I.N.1    Goodwin, A.2    Hoffman, P.S.3
  • 38
    • 59949092493 scopus 로고    scopus 로고
    • Epidemiology of Campylobacter jejuni infections in industrialized nations
    • I. Nachamkin, C. M. Szymanski, and M. J. Blaser ed, 3rd ed. ASM Press, Washington, DC
    • Olson, C. K., S. Ethelberg, W. van Pelt, and R. V. Tauxe. 2008. Epidemiology of Campylobacter jejuni infections in industrialized nations, p. 163-189. In I. Nachamkin, C. M. Szymanski, and M. J. Blaser (ed.), Campylobacter, 3rd ed. ASM Press, Washington, DC.
    • (2008) Campylobacter , pp. 163-189
    • Olson, C.K.1    Ethelberg, S.2    van Pelt, W.3    Tauxe, R.V.4
  • 40
    • 0018800960 scopus 로고
    • Oxygen-sensitive and -insensitive nitroreduction by Escherichia coli and rat hepatic microsomes
    • Peterson, F. J., R. P. Mason, J. Hovsepian, and J. L. Holtzman. 1979. Oxygen-sensitive and -insensitive nitroreduction by Escherichia coli and rat hepatic microsomes. J. Biol. Chem. 254:4009-4014.
    • (1979) J. Biol. Chem , vol.254 , pp. 4009-4014
    • Peterson, F.J.1    Mason, R.P.2    Hovsepian, J.3    Holtzman, J.L.4
  • 41
    • 0029090774 scopus 로고
    • Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus
    • Pollich, M., and G. Klug. 1995. Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus. J. Bacteriol. 177:4481-4487.
    • (1995) J. Bacteriol , vol.177 , pp. 4481-4487
    • Pollich, M.1    Klug, G.2
  • 42
    • 44849085762 scopus 로고    scopus 로고
    • Genetic instability is associated with changes in the colonization potential of Campylobacter jejuni in the avian intestine
    • Ridley, A. M., M. J. Toszeghy, S. A. Cawthraw, T. M. Wassenaar, and D. G. Newell. 2008. Genetic instability is associated with changes in the colonization potential of Campylobacter jejuni in the avian intestine. J. Appl. Microbiol. 105:95-104.
    • (2008) J. Appl. Microbiol , vol.105 , pp. 95-104
    • Ridley, A.M.1    Toszeghy, M.J.2    Cawthraw, S.A.3    Wassenaar, T.M.4    Newell, D.G.5
  • 46
    • 0033811136 scopus 로고    scopus 로고
    • Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (nitroreductase) gene
    • Sisson, G., J. Y. Jeong, A. Goodwin, L. Bryden, N. Rossler, S. Lim-Morrison, A. Raudonikiene, D. E. Berg, and P. S. Hoffman. 2000. Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (nitroreductase) gene. J. Bacteriol. 182:5091-5096.
    • (2000) J. Bacteriol , vol.182 , pp. 5091-5096
    • Sisson, G.1    Jeong, J.Y.2    Goodwin, A.3    Bryden, L.4    Rossler, N.5    Lim-Morrison, S.6    Raudonikiene, A.7    Berg, D.E.8    Hoffman, P.S.9
  • 47
    • 0031738661 scopus 로고    scopus 로고
    • High frequency of metronidazole resistance among strains of Campylobacter jejuni isolated from birds
    • Stanley, K. N., and K. Jones. 1998. High frequency of metronidazole resistance among strains of Campylobacter jejuni isolated from birds. Lett. Appl. Microbiol. 27:247-250.
    • (1998) Lett. Appl. Microbiol , vol.27 , pp. 247-250
    • Stanley, K.N.1    Jones, K.2
  • 48
    • 0034000527 scopus 로고    scopus 로고
    • Frequent association between alteration of the rdxA gene and metronidazole resistance in French and North African isolates of Helicobacter pylori
    • Tankovic, J., D. Lamarque, J. C. Delchier, C. J. Soussy, A. Labigne, and P. J. Jenks. 2000. Frequent association between alteration of the rdxA gene and metronidazole resistance in French and North African isolates of Helicobacter pylori. Antimicrob. Agents Chemother. 44:608-613.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 608-613
    • Tankovic, J.1    Lamarque, D.2    Delchier, J.C.3    Soussy, C.J.4    Labigne, A.5    Jenks, P.J.6
  • 49
    • 0032795933 scopus 로고    scopus 로고
    • Bacteria designed for bioremediation
    • Timmis, K. N., and D. H. Pieper. 1999. Bacteria designed for bioremediation. Trends Biotechnol. 17:200-204.
    • (1999) Trends Biotechnol , vol.17 , pp. 200-204
    • Timmis, K.N.1    Pieper, D.H.2
  • 50
    • 26244452150 scopus 로고    scopus 로고
    • The Helicobacter pylori MutS protein confers protection from oxidative DNA damage
    • Wang, G., P. Alamuri, M. Z. Humayun, D. E. Taylor, and R. J. Maier. 2005. The Helicobacter pylori MutS protein confers protection from oxidative DNA damage. Mol. Microbiol. 58:166-176.
    • (2005) Mol. Microbiol , vol.58 , pp. 166-176
    • Wang, G.1    Alamuri, P.2    Humayun, M.Z.3    Taylor, D.E.4    Maier, R.J.5
  • 51
    • 0028804527 scopus 로고
    • Variation of the flagellin gene locus of Campylobacter jejuni by recombination and horizontal gene transfer
    • Wassenaar, T. M., B. N. Fry, and B. A. van der Zeijst. 1995. Variation of the flagellin gene locus of Campylobacter jejuni by recombination and horizontal gene transfer. Microbiology 141:95-101.
    • (1995) Microbiology , vol.141 , pp. 95-101
    • Wassenaar, T.M.1    Fry, B.N.2    van der Zeijst, B.A.3
  • 52
    • 0031805823 scopus 로고    scopus 로고
    • Evidence of genomic instability in Campylobacter jejuni isolated from poultry
    • Wassenaar, T. M., B. Geilhausen, and D. G. Newell. 1998. Evidence of genomic instability in Campylobacter jejuni isolated from poultry. Appl. Environ. Microbiol. 64:1816-1821.
    • (1998) Appl. Environ. Microbiol , vol.64 , pp. 1816-1821
    • Wassenaar, T.M.1    Geilhausen, B.2    Newell, D.G.3
  • 55
    • 0027327182 scopus 로고
    • Construction of new Campylobacter cloning vectors and a new mutational cat cassette
    • Yao, R., R. A. Alm, T. J. Trust, and P. Guerry. 1993. Construction of new Campylobacter cloning vectors and a new mutational cat cassette. Gene 130:127-130.
    • (1993) Gene , vol.130 , pp. 127-130
    • Yao, R.1    Alm, R.A.2    Trust, T.J.3    Guerry, P.4
  • 56
    • 0029896108 scopus 로고    scopus 로고
    • Molecular cloning and site-specific mutagenesis of a gene involved in arylsulfatase production in Campylobacter jejuni
    • Yao, R., and P. Guerry. 1996. Molecular cloning and site-specific mutagenesis of a gene involved in arylsulfatase production in Campylobacter jejuni. J. Bacteriol. 178:3335-3338.
    • (1996) J. Bacteriol , vol.178 , pp. 3335-3338
    • Yao, R.1    Guerry, P.2
  • 57
    • 0029808844 scopus 로고    scopus 로고
    • Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri
    • Zenno, S., H. Koike, M. Tanokura, and K. Saigo. 1996. Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri. J. Biochem. 120:736-744.
    • (1996) J. Biochem , vol.120 , pp. 736-744
    • Zenno, S.1    Koike, H.2    Tanokura, M.3    Saigo, K.4
  • 58
    • 0028340512 scopus 로고
    • Identification of the gene encoding the major NAD(P)H-flavin oxidoreductase of the bioluminescent bacterium Vibrio fischeri ATCC 7744
    • Zenno, S., K. Saigo, H. Kanoh, and S. Inouye. 1994. Identification of the gene encoding the major NAD(P)H-flavin oxidoreductase of the bioluminescent bacterium Vibrio fischeri ATCC 7744. J. Bacteriol. 176:3536-3543.
    • (1994) J. Bacteriol , vol.176 , pp. 3536-3543
    • Zenno, S.1    Saigo, K.2    Kanoh, H.3    Inouye, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.