Label-free imaging of heme proteins with two-photon excited photothermal lens microscopy

Applied Physics Letters

Volumn 96, Issue 11, 2010, Pages

  Lu, Sijia ^a   Min, Wei ^a   Chong, Shasha ^a   Holtom, Gary R ^a   Xie, X Sunney ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A-THERMAL; BIOLOGICAL PROCESS; CONTRAST MECHANISM; HEME PROTEINS; HIGH FREQUENCY MODULATION; LABEL FREE; MAMMALIAN CELLS; MICROVASCULAR NETWORK; PHOTO-THERMAL; PHOTOTHERMAL EFFECTS; RED BLOOD CELL; SUBCELLULAR DISTRIBUTION; TWO-PHOTON EXCITED; ZEBRAFISH;

BLOOD; FREQUENCY MODULATION; LABELS; LENSES; MAMMALS; OPTICAL INSTRUMENTS; PHOTONS; PORPHYRINS; SIGNAL TO NOISE RATIO;

HEMOGLOBIN;

EID: 77949685702     PISSN: 00036951     EISSN: None     Source Type: Journal    
DOI: 10.1063/1.3308485     Document Type: Article

References (20)

1. D. M. McDonald and P. L. Choyke, Nat. Med. 1078-8956 9, 713 (2003). 10.1038/nm0603-713
2. X. Jiang and X. Wang, Annu. Rev. Biochem. 0066-4154 73, 87 (2004). 10.1146/annurev.biochem.73.011303.073706
3. P. M. Champion and G. J. Perreault, J. Chem. Phys. 0021-9606 75, 490 (1981). 10.1063/1.441846
4. R. Jimenez and F. E. Romesberg, J. Phys. Chem. B 1089-5647 106, 9172 (2002). 10.1021/jp0209648
5. S. E. Bialkowski, Photothermal Spectroscopy Methods for Chemical Analysis (Wiley, New York, 1996).
6. M. Tokeshi, M. Uchida, A. Hibara, T. Sawada, and T. Kitamori, Anal. Chem. 0003-2700 73, 2112 (2001). 10.1021/ac001479g
7. D. Boyer, P. Tamarat, A. Maali, B. Lounis, and M. Orrit, Science 0036-8075 297, 1160 (2002). 10.1126/science.1073765
8. L. Cognet, C. Tardin, D. Boyer, D. Choquet, P. Tamarat, and B. Lounis, Proc. Natl. Acad. Sci. U.S.A. 0027-8424 100, 11350 (2003). 10.1073/pnas. 1534635100
9. A. V. Brusnichkin, D. A. Nedosekin, M. A. Proskurnin, and V. P. Zharov, Appl. Spectrosc. 0003-7028 61, 1191 (2007). 10.1366/000370207782597175
10. W. Denk, J. H. Strickler, and W. W. Webb, Science 0036-8075 248, 73 (1990). 10.1126/science.2321027
11. G. O. Clay, C. B. Schaffer, and D. Kleinfeld, J. Chem. Phys. 0021-9606 126, 025102 (2007). 10.1063/1.2404678
12. See supplementary material at http://dx.doi.org/10.1063/1.3308485 E-APPLAB-96-017006 for detailed experimental setups and sample preparations.
13. C. W. Freudiger, W. Min, B. G. Saar, S. Lu, G. R. Holtom, C. He, J. C. Tsai, J. X. Kang, and X. S. Xie, Science 0036-8075 322, 1857 (2008). 10.1126/science.1165758
14. W. Min, S. Lu, S. Chong, R. Roy, G. R. Holtom, and X. S. Xie, Nature (London) 0028-0836 461, 1105 (2009). 10.1038/nature08438
15. S. A. Detmer and D. C. Chan, Nat. Rev. Mol. Cell Biol. 1471-0072 8, 870 (2007). 10.1038/nrm2275
16. E. W. Stein, K. Maslov, and L. V. Wang, J. Biomed. Opt. 1083-3668 14, 020502 (2009). 10.1117/1.3095799
17. C. B. Schaffer, B. Friedman, N. Nishimura, L. F. Schroeder, P. S. Tsai, F. F. Ebner, P. D. Lyden, and D. Kleinfeld, PLoS Biol. 1545-7885 4, e22 (2006). 10.1371/journal.pbio.0040022
18. A. Monfared, N. H. Blevins, E. L. Cheung, J. C. Jung, G. Popelka, and M. J. Schnitzer, Otol. Neurotol. 1531-7129 27, 144 (2006). 10.1097/01.mao. 0000190708.44067.b0
19. K. Stoletov, V. Montel, R. D. Lester, S. L. Gonias, and R. Klemke, Proc. Natl. Acad. Sci. U.S.A. 0027-8424 104, 17406 (2007). 10.1073/pnas.0703446104
20. D. Fu, T. Ye, T. E. Matthews, B. J. Chen, G. Yurtserver, and W. S. Warren, Opt. Lett. 0146-9592 32, 2641 (2007). 10.1364/OL.32.002641