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Volumn 7, Issue 1, 2010, Pages 51-64

Formulation optimization of etoposide loaded PLGA nanoparticles by double factorial design and their evaluation

Author keywords

32 Factorial design, Sustained release; Etoposide; Nanoparticles; PLGA; Stability studies

Indexed keywords

ETOPOSIDE; NANOPARTICLE; POLYMER; SUCROSE;

EID: 77949662784     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720110790396517     Document Type: Article
Times cited : (87)

References (28)
  • 1
    • 0025265751 scopus 로고
    • Etoposide: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in combination chemotherapy of cancer
    • Henwood, J. M.; Brogden, R. N. Etoposide: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in combination chemotherapy of cancer. Drugs, 1990, 39, 438-490.
    • (1990) Drugs , vol.39 , pp. 438-490
    • Henwood, J.M.1    Brogden, R.N.2
  • 2
    • 0018737940 scopus 로고
    • Biodegradable polymers for use in surgery-poly(glycolic)/poly(lactic acid) homo and copolymers
    • Gilding, D. K.; Reed, A. M. Biodegradable polymers for use in surgery-poly(glycolic)/poly(lactic acid) homo and copolymers. Polymer, 1979, 20, 1459-1464.
    • (1979) Polymer , vol.20 , pp. 1459-1464
    • Gilding, D.K.1    Reed, A.M.2
  • 3
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive, M. S.; Anderson, J. M. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev., 1997, 28, 5-24.
    • (1997) Adv. Drug Deliv. Rev , vol.28 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 4
    • 0040822552 scopus 로고
    • An introduction to design, data analysis and model building
    • Wiley: NewYork
    • Box, G.; Hunter, W.; Hunter, J. An introduction to design, data analysis and model building. In: Statistics for Experimenters; Wiley: NewYork, 1978, pp. 510-520.
    • (1978) Statistics for Experimenters , pp. 510-520
    • Box, G.1    Hunter, W.2    Hunter, J.3
  • 5
    • 0037093720 scopus 로고    scopus 로고
    • Biocompatible stabilizers in the preparation of PLGA nanoparticles: A factorial design study
    • Vandervoort, J.; Ludwig, A. Biocompatible stabilizers in the preparation of PLGA nanoparticles: a factorial design study. Int. J. Pharm., 2002, 238, 77-92.
    • (2002) Int. J. Pharm , vol.238 , pp. 77-92
    • Vandervoort, J.1    Ludwig, A.2
  • 6
    • 0032767088 scopus 로고    scopus 로고
    • Biodegradable nanoparticles containing PLGA conjugate for sustained release
    • Yoo, H. S.; Oh, J. E.; Lee, K. H.; Park, T. G. Biodegradable nanoparticles containing PLGA conjugate for sustained release. Pharm. Res., 1999, 16, 1114-1118.
    • (1999) Pharm. Res , vol.16 , pp. 1114-1118
    • Yoo, H.S.1    Oh, J.E.2    Lee, K.H.3    Park, T.G.4
  • 7
    • 0034957546 scopus 로고    scopus 로고
    • Preparation factors affecting the properties of polylactide nanoparticles: A factorial design study
    • Vandervoort, J.; Ludwig, A., Preparation factors affecting the properties of polylactide nanoparticles: a factorial design study. Pharmazie, 2001, 56, 484-488.
    • (2001) Pharmazie , vol.56 , pp. 484-488
    • Vandervoort, J.1    Ludwig, A.2
  • 8
    • 0032743871 scopus 로고    scopus 로고
    • Response surface methodology as a predictive tool for determining the effects of preparation conditions on the physicochemical properties of poly(isobutylcyanoacrylate) nanoparticles
    • McCarron, P. A.; Woolfson, A. D.; Keating, S. M. Response surface methodology as a predictive tool for determining the effects of preparation conditions on the physicochemical properties of poly(isobutylcyanoacrylate) nanoparticles. Int. J. Pharm., 1999, 193, 37-47.
    • (1999) Int. J. Pharm , vol.193 , pp. 37-47
    • McCarron, P.A.1    Woolfson, A.D.2    Keating, S.M.3
  • 9
    • 2442697409 scopus 로고    scopus 로고
    • In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form
    • Leo, E.; Brina, B.; Forni, F.; Vandelli, M. A. In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form. Int. J. Pharm., 2004, 278, 133-141.
    • (2004) Int. J. Pharm , vol.278 , pp. 133-141
    • Leo, E.1    Brina, B.2    Forni, F.3    Vandelli, M.A.4
  • 11
    • 0021904208 scopus 로고
    • Analysis of fickian and non-fickian drug release from polymers
    • Peppas, N. A. Analysis of fickian and non-fickian drug release from polymers. Pharm. Acta. Helv., 1985, 60, 110-111.
    • (1985) Pharm. Acta. Helv , vol.60 , pp. 110-111
    • Peppas, N.A.1
  • 12
    • 27744443754 scopus 로고    scopus 로고
    • Etoposide-loaded nanoparticles made from glyceride lipids: Formulation, characterization, in vitro drug release, and stability evaluation
    • E-158-E166
    • Reddy, L. H.; Murthy, R.S.R. Etoposide-loaded nanoparticles made from glyceride lipids: formulation, characterization, in vitro drug release, and stability evaluation. AAPS Pharm. Sci. Tech., 2005, 6(2), E-158-E166.
    • (2005) AAPS Pharm. Sci. Tech , vol.6 , Issue.2
    • Reddy, L.H.1    Murthy, R.S.R.2
  • 13
    • 0343407048 scopus 로고    scopus 로고
    • Spray-drying of solid lipid nanoparticles (SLN)
    • Freitas, C.; Muller, R. H. Spray-drying of solid lipid nanoparticles (SLN). Eur. J. Pharm. Biopharm., 1998, 46, 145-151.
    • (1998) Eur. J. Pharm. Biopharm , vol.46 , pp. 145-151
    • Freitas, C.1    Muller, R.H.2
  • 14
    • 0037018971 scopus 로고    scopus 로고
    • Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration
    • Ahlin, P.; Kristl, J.; Kristl, A.; Vrecer, F. Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration. Int. J. Pharm., 2002, 239, 113-120.
    • (2002) Int. J. Pharm , vol.239 , pp. 113-120
    • Ahlin, P.1    Kristl, J.2    Kristl, A.3    Vrecer, F.4
  • 15
    • 0017280570 scopus 로고
    • Analysis and selection of variables in linear regression
    • Hocking, R. R. Analysis and selection of variables in linear regression. Biometrics, 1976, 32, 1-49.
    • (1976) Biometrics , vol.32 , pp. 1-49
    • Hocking, R.R.1
  • 16
    • 4243513277 scopus 로고    scopus 로고
    • Introduction to factorial designs
    • John Wiley Sons, New York
    • Montegomery, D. C. Introduction to factorial designs. In: Design and Analysis of Experiments; John Wiley Sons, New York, 2004, pp. 392-426.
    • (2004) Design and Analysis of Experiments , pp. 392-426
    • Montegomery, D.C.1
  • 17
    • 0033776698 scopus 로고    scopus 로고
    • Two-time window and multiangle photon correlation spectroscopy size and zeta potential analysis-highly sensitive rapid assay for dispersion stability
    • Thode, K.; Muller, R. H.; Kresse, M. Two-time window and multiangle photon correlation spectroscopy size and zeta potential analysis-highly sensitive rapid assay for dispersion stability. J. Pharm. Sci., 2000, 89, 1317-1324.
    • (2000) J. Pharm. Sci , vol.89 , pp. 1317-1324
    • Thode, K.1    Muller, R.H.2    Kresse, M.3
  • 18
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing - Oral formulation development and biopharmaceutical evaluation
    • Kesisoglou, F.; Panmai, S.; Wu, Y. Nanosizing - Oral formulation development and biopharmaceutical evaluation. Adv. Drug Deliv. Rev., 2007, 59, 631-644.
    • (2007) Adv. Drug Deliv. Rev , vol.59 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 20
    • 0036244898 scopus 로고    scopus 로고
    • Development of biodegradable microcapsules as carrier for oral controlled delivery of amifostine
    • Mandal, T. K.; Bostanian, L. A.; Graves, R. A.; Chapman, S. R.; Womack, I. Development of biodegradable microcapsules as carrier for oral controlled delivery of amifostine. Drug Dev. Ind. Pharm., 2002, 28, 339- 344.
    • (2002) Drug Dev. Ind. Pharm , vol.28 , pp. 339-344
    • Mandal, T.K.1    Bostanian, L.A.2    Graves, R.A.3    Chapman, S.R.4    Womack, I.5
  • 21
    • 0025731293 scopus 로고
    • Controlled delivery system for proteins based on poly (lactic/glycolic acid) microspheres
    • Cohen, S.; Yoshiaka, T.; Lucarelli, M. Controlled delivery system for proteins based on poly (lactic/glycolic acid) microspheres. Pharm. Res., 1991, 8, 713-720.
    • (1991) Pharm. Res , vol.8 , pp. 713-720
    • Cohen, S.1    Yoshiaka, T.2    Lucarelli, M.3
  • 22
    • 1542328830 scopus 로고    scopus 로고
    • Optimisation of aciclovir poly(d,l-lactide-co-glycolide) microspheres for intravitreal administration using a factorial design study
    • Martinez-Sancho, C.; Herrero-Vanrell, R.; Negro, S. Optimisation of aciclovir poly(d,l-lactide-co-glycolide) microspheres for intravitreal administration using a factorial design study. Int. J. Pharm., 2004, 273, 45-56
    • (2004) Int. J. Pharm , vol.273 , pp. 45-56
    • Martinez-Sancho, C.1    Herrero-Vanrell, R.2    Negro, S.3
  • 23
    • 0037202148 scopus 로고    scopus 로고
    • Lipophilic drug loaded nanospheres prepared by nanoparecipitation: Effect of formulating variables on size, drug recovery and release kinetics
    • Chorny, M.; Fishbein, I.; Danenberg, H. D.; Golomb G. Lipophilic drug loaded nanospheres prepared by nanoparecipitation: effect of formulating variables on size, drug recovery and release kinetics. J. Control. Rel., 2002, 83, 389-400.
    • (2002) J. Control. Rel , vol.83 , pp. 389-400
    • Chorny, M.1    Fishbein, I.2    Danenberg, H.D.3    Golomb, G.4
  • 24
    • 0029130253 scopus 로고
    • Degradation of poly (lactide-co-glycolide acid) microspheres: Effect of copolymer composition
    • Park, T. G. Degradation of poly (lactide-co-glycolide acid) microspheres: effect of copolymer composition. Biomaterials, 1995, 16, 1123-1130.
    • (1995) Biomaterials , vol.16 , pp. 1123-1130
    • Park, T.G.1
  • 25
    • 0028820207 scopus 로고
    • In vitro evaluation of polyisobutylcyanoacrylate nanoparticles as a controlled drug carrier for theophylline
    • Radwan, M. A. In vitro evaluation of polyisobutylcyanoacrylate nanoparticles as a controlled drug carrier for theophylline. Drug Dev. Ind. Pharm., 1995, 21, 2371-2375.
    • (1995) Drug Dev. Ind. Pharm , vol.21 , pp. 2371-2375
    • Radwan, M.A.1
  • 26
    • 0035844738 scopus 로고    scopus 로고
    • Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)
    • Siepmann, J.; Peppas, N. A. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv. Drug Deliv. Rev., 2001, 48, 139-157.
    • (2001) Adv. Drug Deliv. Rev , vol.48 , pp. 139-157
    • Siepmann, J.1    Peppas, N.A.2
  • 27
    • 0032473386 scopus 로고    scopus 로고
    • Formulation of Lasparaginase-loaded poly(lactide-co-glycolide) nanoparticles: Influence of polymer properties on enzyme loading, activity and in vitro release
    • Gasper, M. M.; Blanco, D.; Cruz, M. E.; Alonso, M. J. Formulation of Lasparaginase-loaded poly(lactide-co-glycolide) nanoparticles: influence of polymer properties on enzyme loading, activity and in vitro release. J. Control. Release, 1998, 52, 53-62.
    • (1998) J. Control. Release , vol.52 , pp. 53-62
    • Gasper, M.M.1    Blanco, D.2    Cruz, M.E.3    Alonso, M.J.4
  • 28
    • 0034036366 scopus 로고    scopus 로고
    • Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles
    • Dunne, M.; Corrigan, O. I.; Ramtoola, Z. Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles. Biomaterials, 2000, 21, 1659-1668.
    • (2000) Biomaterials , vol.21 , pp. 1659-1668
    • Dunne, M.1    Corrigan, O.I.2    Ramtoola, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.