-
1
-
-
0026644391
-
High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains
-
Margolis B, Silvennoinen O, Comoglio F et al. High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proc Natl Acad Sci U S A 1992; 89: 8894-8898.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8894-8898
-
-
Margolis, B.1
Silvennoinen, O.2
Comoglio, F.3
-
2
-
-
0037047324
-
Association of Grb7 with phosphoinositides and its role in the regulation of cell migration
-
Shen TL, Han DC, Guan JL. Association of Grb7 with phosphoinositides and its role in the regulation of cell migration. J Biol Chem 2002; 277: 29069-29077.
-
(2002)
J Biol Chem
, vol.277
, pp. 29069-29077
-
-
Shen, T.L.1
Han, D.C.2
Guan, J.L.3
-
3
-
-
0031713878
-
The Grb7 family of signalling proteins
-
Daly RJ. The Grb7 family of signalling proteins. Cell Signal 1998; 10: 613-618.
-
(1998)
Cell Signal
, vol.10
, pp. 613-618
-
-
Daly, R.J.1
-
4
-
-
0035473462
-
The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions
-
Han DC, Shen TL, Guan JL. The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions. Oncogene 2001; 20: 6315-6321.
-
(2001)
Oncogene
, vol.20
, pp. 6315-6321
-
-
Han, D.C.1
Shen, T.L.2
Guan, J.L.3
-
5
-
-
32144453306
-
Adapter protein connections: the MRL and Grb7 protein families
-
Holt LJ, Daly RJ. Adapter protein connections: the MRL and Grb7 protein families. Growth Factors 2005; 23: 193-201.
-
(2005)
Growth Factors
, vol.23
, pp. 193-201
-
-
Holt, L.J.1
Daly, R.J.2
-
6
-
-
2542490290
-
Grb7 in intracellular signaling and its role in cell regulation
-
Shen TL, Guan JL. Grb7 in intracellular signaling and its role in cell regulation. Front Biosci 2004; 9: 192-200.
-
(2004)
Front Biosci
, vol.9
, pp. 192-200
-
-
Shen, T.L.1
Guan, J.L.2
-
8
-
-
0028252996
-
The GRB family of SH2 domain proteins
-
Margolis B. The GRB family of SH2 domain proteins. Prog Biophys Mol Biol 1994; 62: 223-244.
-
(1994)
Prog Biophys Mol Biol
, vol.62
, pp. 223-244
-
-
Margolis, B.1
-
9
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen GB, Ren R, Baltimore D. Modular binding domains in signal transduction proteins. Cell 1995; 80: 237-248.
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
10
-
-
0035575586
-
SH2 domains, interaction modules and cellular wiring
-
Pawson T, Gish GD, Nash P. SH2 domains, interaction modules and cellular wiring. Trends Cell Biol 2001; 11: 504-511.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 504-511
-
-
Pawson, T.1
Gish, G.D.2
Nash, P.3
-
11
-
-
0028343550
-
The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer
-
Stein D, Wu J, Fuqua SA et al. The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer. Embo J 1994; 13: 1331-1340.
-
(1994)
Embo J
, vol.13
, pp. 1331-1340
-
-
Stein, D.1
Wu, J.2
Fuqua, S.A.3
-
12
-
-
33947733439
-
The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer
-
Gullick WJ. The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer. Int J Cancer Suppl 1990; 5: 55-61.
-
(1990)
Int J Cancer Suppl
, vol.5
, pp. 55-61
-
-
Gullick, W.J.1
-
13
-
-
0030614746
-
Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains
-
Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE. Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains. J Biol Chem 1997; 272: 2659-2667.
-
(1997)
J Biol Chem
, vol.272
, pp. 2659-2667
-
-
Frantz, J.D.1
Giorgetti-Peraldi, S.2
Ottinger, E.A.3
Shoelson, S.E.4
-
14
-
-
0037160059
-
EphB1 associates with Grb7 and regulates cell migration
-
Han DC, Shen TL, Miao H et al. EphB1 associates with Grb7 and regulates cell migration. J Biol Chem 2002; 277: 45655-45661.
-
(2002)
J Biol Chem
, vol.277
, pp. 45655-45661
-
-
Han, D.C.1
Shen, T.L.2
Miao, H.3
-
15
-
-
0034666146
-
Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
-
Han DC, Shen TL, Guan JL. Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration. J Biol Chem 2000; 275: 28911-28917.
-
(2000)
J Biol Chem
, vol.275
, pp. 28911-28917
-
-
Han, D.C.1
Shen, T.L.2
Guan, J.L.3
-
16
-
-
0000226650
-
Association of focal adhesion kinase with Grb7 and its role in cell migration
-
Han DC, Guan JL. Association of focal adhesion kinase with Grb7 and its role in cell migration. J Biol Chem 1999; 274: 24425-24430.
-
(1999)
J Biol Chem
, vol.274
, pp. 24425-24430
-
-
Han, D.C.1
Guan, J.L.2
-
17
-
-
0028144080
-
SH2 and SH3 domains in signal transduction
-
Pawson T. SH2 and SH3 domains in signal transduction. Adv Cancer Res 1994; 64: 87-110.
-
(1994)
Adv Cancer Res
, vol.64
, pp. 87-110
-
-
Pawson, T.1
-
18
-
-
0032571234
-
Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3
-
Fiddes RJ, Campbell DH, Janes PW et al. Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3. J Biol Chem 1998; 273: 7717-7724.
-
(1998)
J Biol Chem
, vol.273
, pp. 7717-7724
-
-
Fiddes, R.J.1
Campbell, D.H.2
Janes, P.W.3
-
19
-
-
2442689239
-
Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate
-
Rodriguez-Viciana P, Sabatier C, McCormick F. Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate. Mol Cell Biol 2004; 24: 4943-4954.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4943-4954
-
-
Rodriguez-Viciana, P.1
Sabatier, C.2
McCormick, F.3
-
20
-
-
0034056773
-
Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma
-
Tanaka S, Sugimachi K, Kawaguchi H et al. Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma. J Cell Physiol 2000; 183: 411-415.
-
(2000)
J Cell Physiol
, vol.183
, pp. 411-415
-
-
Tanaka, S.1
Sugimachi, K.2
Kawaguchi, H.3
-
21
-
-
0032528990
-
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
-
Tanaka S, Mori M, Akiyoshi T et al. A novel variant of human Grb7 is associated with invasive esophageal carcinoma. J Clin Invest 1998; 102: 821-827.
-
(1998)
J Clin Invest
, vol.102
, pp. 821-827
-
-
Tanaka, S.1
Mori, M.2
Akiyoshi, T.3
-
22
-
-
34248525627
-
Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells
-
Pero SC, Shukla GS, Cookson MM et al. Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells. Br J Cancer 2007; 96: 1520-1525.
-
(2007)
Br J Cancer
, vol.96
, pp. 1520-1525
-
-
Pero, S.C.1
Shukla, G.S.2
Cookson, M.M.3
-
23
-
-
0035890381
-
New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays
-
Kauraniemi P, Barlund M, Monni O, Kallioniemi A. New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays. Cancer Res 2001; 61: 8235-8240.
-
(2001)
Cancer Res
, vol.61
, pp. 8235-8240
-
-
Kauraniemi, P.1
Barlund, M.2
Monni, O.3
Kallioniemi, A.4
-
24
-
-
0142244153
-
Amplification of a 280-kilobase core region at the ERBB2 locus leads to activation of two hypothetical proteins in breast cancer
-
Kauraniemi P, Kuukasjarvi T, Sauter G, Kallioniemi A. Amplification of a 280-kilobase core region at the ERBB2 locus leads to activation of two hypothetical proteins in breast cancer. Am J Pathol 2003; 163: 1979-1984.
-
(2003)
Am J Pathol
, vol.163
, pp. 1979-1984
-
-
Kauraniemi, P.1
Kuukasjarvi, T.2
Sauter, G.3
Kallioniemi, A.4
-
25
-
-
0036648452
-
Amplification and expression of genes from the 17q11 approximately q12 amplicon in breast cancer cells
-
Luoh SW. Amplification and expression of genes from the 17q11 approximately q12 amplicon in breast cancer cells. Cancer Genet Cytogenet 2002; 136: 43-47.
-
(2002)
Cancer Genet Cytogenet
, vol.136
, pp. 43-47
-
-
Luoh, S.W.1
-
26
-
-
0042524268
-
Prognostic value of ERBB family mRNA expression in breast carcinomas
-
Bieche I, Onody P, Tozlu S et al. Prognostic value of ERBB family mRNA expression in breast carcinomas. Int J Cancer 2003; 106: 758-765.
-
(2003)
Int J Cancer
, vol.106
, pp. 758-765
-
-
Bieche, I.1
Onody, P.2
Tozlu, S.3
-
27
-
-
28544452730
-
Expression of HER2 and the coamplified genes Grb7 and MLN64 in human breast cancer: quantitative real-time reverse transcription-PCR as a diagnostic alternative to immunohistochemistry and fluorescence in situ hybridization
-
Vinatzer U, Dampier B, Streubel B et al. Expression of HER2 and the coamplified genes Grb7 and MLN64 in human breast cancer: quantitative real-time reverse transcription-PCR as a diagnostic alternative to immunohistochemistry and fluorescence in situ hybridization. Clin Cancer Res 2005; 11: 8348-8357.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8348-8357
-
-
Vinatzer, U.1
Dampier, B.2
Streubel, B.3
-
28
-
-
29344451417
-
Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes
-
Cobleigh MA, Tabesh B, Bitterman P et al. Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes. Clin Cancer Res 2005; 11: 8623-8631.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8623-8631
-
-
Cobleigh, M.A.1
Tabesh, B.2
Bitterman, P.3
-
29
-
-
40949086031
-
GRB-7 facilitates HER-2/neu-mediated signal transduction and tumor formation
-
Bai T, Luoh SW. GRB-7 facilitates HER-2/neu-mediated signal transduction and tumor formation. Carcinogenesis 2008; 29: 473-479.
-
(2008)
Carcinogenesis
, vol.29
, pp. 473-479
-
-
Bai, T.1
Luoh, S.W.2
-
30
-
-
33745686009
-
RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes
-
Kao J, Pollack JR. RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes. Genes Chromosomes Cancer 2006; 45: 761-769.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 761-769
-
-
Kao, J.1
Pollack, J.R.2
-
31
-
-
0037023768
-
Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7
-
Pero SC, Oligino L, Daly RJ et al. Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7. J Biol Chem 2002; 277: 11918-11926.
-
(2002)
J Biol Chem
, vol.277
, pp. 11918-11926
-
-
Pero, S.C.1
Oligino, L.2
Daly, R.J.3
-
32
-
-
33645735705
-
Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis
-
Tanaka S, Pero SC, Taguchi K et al. Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis. J Natl Cancer Inst 2006; 98: 491-498.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 491-498
-
-
Tanaka, S.1
Pero, S.C.2
Taguchi, K.3
-
33
-
-
0037099532
-
Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
-
Yakes FM, Chinratanalab W, Ritter CA et al. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res 2002; 62: 4132-4141.
-
(2002)
Cancer Res
, vol.62
, pp. 4132-4141
-
-
Yakes, F.M.1
Chinratanalab, W.2
Ritter, C.A.3
-
34
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik S, Shak S, Tang G et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004; 351: 2817-2826.
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
-
35
-
-
33744938180
-
Quantitative in situ analysis of betacatenin expression in breast cancer shows decreased expression is associated with poor outcome
-
Dolled-Filhart M, McCabe A, Giltnane J et al. Quantitative in situ analysis of betacatenin expression in breast cancer shows decreased expression is associated with poor outcome. Cancer Res 2006; 66: 5487-5494.
-
(2006)
Cancer Res
, vol.66
, pp. 5487-5494
-
-
Dolled-Filhart, M.1
McCabe, A.2
Giltnane, J.3
-
36
-
-
0036852721
-
Automated subcellular localization and quantification of protein expression in tissue microarrays
-
Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 2002; 8: 1323-1327.
-
(2002)
Nat Med
, vol.8
, pp. 1323-1327
-
-
Camp, R.L.1
Chung, G.G.2
Rimm, D.L.3
-
37
-
-
48949119483
-
Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer
-
Nadler Y, Camp RL, Giltnane JM et al. Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer. Breast Cancer Res 2008; 10: R35.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Nadler, Y.1
Camp, R.L.2
Giltnane, J.M.3
-
38
-
-
85198904462
-
Two-dimensional goodness-of-fit testing in astronomy
-
Peacock J. Two-dimensional goodness-of-fit testing in astronomy. Mon Not R Astr Soc 1983; 202: 615-627.
-
(1983)
Mon Not R Astr Soc
, vol.202
, pp. 615-627
-
-
Peacock, J.1
-
39
-
-
0030693661
-
Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer
-
Fisher B, Dignam J, Wolmark N et al. Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer. J Natl Cancer Inst 1997; 89: 1673-1682.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1673-1682
-
-
Fisher, B.1
Dignam, J.2
Wolmark, N.3
-
40
-
-
0035865147
-
Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-23
-
Fisher B, Anderson S, Tan-Chiu E et al. Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-23. J Clin Oncol 2001; 19: 931-942.
-
(2001)
J Clin Oncol
, vol.19
, pp. 931-942
-
-
Fisher, B.1
Anderson, S.2
Tan-Chiu, E.3
-
41
-
-
0031684721
-
The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy
-
Ross JS, Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist 1998; 3: 237-252.
-
(1998)
Oncologist
, vol.3
, pp. 237-252
-
-
Ross, J.S.1
Fletcher, J.A.2
-
43
-
-
33846627223
-
Progress and new standards of care in the management of HER-2 positive breast cancer
-
Demonty G, Bernard-Marty C, Puglisi F et al. Progress and new standards of care in the management of HER-2 positive breast cancer. Eur J Cancer 2007; 43: 497-509.
-
(2007)
Eur J Cancer
, vol.43
, pp. 497-509
-
-
Demonty, G.1
Bernard-Marty, C.2
Puglisi, F.3
-
44
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
45
-
-
55749101607
-
Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors
-
Sunami E, Shinozaki M, Sim MS et al. Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. Breast Cancer Res 2008; 10: R46.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Sunami, E.1
Shinozaki, M.2
Sim, M.S.3
-
46
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999; 17: 2639-2648.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
47
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353: 1659-1672.
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
|