C3d and the Septal Microvasculature as a Predictor of Chronic Lung Allograft Dysfunction

Human Immunology

Volumn 67, Issue 4-5, 2006, Pages 274-283

  Magro, Cynthia M ^a   Abbas, Abbas E ^a   Seilstad, Kay ^a   Pope Harman, Amy L ^a   Nadasdy, Tibor ^a   Ross Jr , Patrick ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

C3d deposition; chronic graft dysfunction; Lung transplantation

Indexed keywords

COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C4D; CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS;

ARTICLE; BRONCHIOLITIS OBLITERANS; CLINICAL ARTICLE; COMPLEMENT DEPOSITION; CONTROLLED STUDY; GRAFT DYSFUNCTION; GRAFT FAILURE; HUMAN; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LUNG BIOPSY; LUNG FIBROSIS; LUNG TRANSPLANTATION; MICROVASCULATURE; PRIORITY JOURNAL;

CAPILLARIES; CHRONIC DISEASE; COMPLEMENT C3D; COMPLEMENT C4; CRYOPRESERVATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GRAFT REJECTION; HUMANS; LUNG; LUNG TRANSPLANTATION; MALE; PARAFFIN EMBEDDING;

EID: 33646546047     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2005.11.001     Document Type: Article

References (20)

1. Magro C.M., Deng A., Pope-Harman A., Waldman W.J., Bernard Collins A., Adams P.W., Kelsey M., and Ross P. Humorally mediated posttransplantation septal capillary injury syndrome as a common form of pulmonary allograft rejection. a hypothesis. Transplantation 74 (2002) 1273 Erratum in: Transplantation 76:1009, 2003
2. Magro C.M., Ross Jr. P., Kelsey M., Waldman W.J., and Pope-Harman A. Association of humoral immunity and bronchiolitis obliterans syndrome. Am J Transplant 3 (2003) 1155
3. Magro C.M., Klinger D.M., Adams P.W., Orosz C.G., Pope-Harman A.L., Waldman W.J., Knight D., and Ross Jr. P. Evidence that humoral allograft rejection in lung transplant patients is not histocompatibility antigen-related. Am J Transplant 3 (2003) 1264
4. Magro C.M., Pope Harman A., Klinger D., Orosz C., Adams P., Waldman J., Knight D., Kelsey M., and Ross Jr. P. Use of C4d as a diagnostic adjunct in lung allograft biopsies. Am J Transplant 3 (2003) 1143
5. Miller G.G., Destarac L., Zeevi A., Girnita A., McCurry K., Iacono A., Murray J.J., Crowe D., Johnson J.E., Ninan M., and Milstone A.P. Acute humoral rejection of human lung allografts and elevation of C4d in bronchoalveolar lavage fluid. Am J Transplant 4 (2004) 1323
6. Kuypers D.R., Lerut E., Evenepoel P., Maes B., Vanrenterghem Y., and Van Damme B. C3D deposition in peritubular capillaries indicates a variant of acute renal allograft rejection characterized by a worse clinical outcome. Transplantation 76 (2003) 102
7. Magro C.M., Schusterman B., Nadadsy T., Calomeni E., Pope-Harman A., and Ross P. The role of ultrastructure as a diagnostic adjunct in lung allograft biopsies. Ultrastructural Pathology 29 (2005) 95-106
8. Rose M.L. Anti-vimentin antibodies are an independent predictor of transplant-associated coronary artery disease following cardiac transplantation. Ital Heart J 2 Suppl 3 (2001) 23S
9. Rose M.L. Role of antibodies in transplant-associated cardiac allograft vasculopathy. Z Kardiol 89 Suppl 9 (2000) IX/11
10. Wheeler C.H., Collins A., Dunn M.J., Crisp S.J., Yacoub M.H., and Rose M.L. Characterization of endothelial antigens associated with transplant-associated coronary artery disease. J Heart Lung Transplant 14 (1995) S188
11. Muller T.F., Kraus M., Neumann C., and Lange H. Detection of renal allograft rejection by complement components C5A and TCC in plasma and urine. J Lab Clin Med 129 (1997) 62
12. Bechtel U., Scheuer R., Landgraf R., Konig A., and Feucht H.E. Assessment of soluble adhesion molecules (sICAM-1, sVCAM-1, sELAM-1) and complement cleavage products (sC4d, sC5b-9) in urine. Clinical monitoring of renal allograft recipients. Transplantation 58 (1994) 905
13. Mollnes T.E., Lea T., Frøland S.S., and Harboe M. Quantification of the terminal complement complex in human plasma by an enzyme-linked immunosorbent assay based on monoclonal antibodies against a neoantigen of the complex. Scand J Immunol 22 (1985) 197
14. Palmer S.M., Burch L.H., Trindade A.J., Davis R.D., Herczyk W.F., Reinsmoen N.L., and Schwartz D.A. Innate immunity influences long-term outcomes after human lung transplant. Am J Respir Crit Care Med 171 (2005) 780
15. Lee E.K., Kang S.M., Paik D.J., Kim J.M., and Youn J. Essential roles of Toll-like receptor-4 signaling in arthritis induced by type II collagen antibody and LPS. Int Immunol 17 (2005) 325
16. Dempsey P.W., Allison M.E., Akkaraju S., Goodnow C.C., and Fearon D.T. C3d of complement as a molecular adjuvant. bridging innate and acquired immunity. Science 271 (1996) 348
17. Carroll M.C., and Prodeus A.P. Linkages of innate and adaptive immunity. Curr Opin Immunol 10 (1998) 36
18. Toapanta F.R., and Ross T.M. Mouse strain-dependent differences in enhancement of immune responses by C3d. Vaccine 22 (2004) 1773
19. Baldwin III W.M., Samaniego-Picota M., Kasper E.K., Clark A.M., Czader M., Rohde C., Zachary A.A., Sanfilippo F., and Hruban R.H. Complement deposition in early cardiac transplant biopsies is associated with ischemic injury and subsequent rejection episodes. Transplantation 68 (1999) 894
20. Eggertsen G., Nyberg G., Nilsson B., Nilsson U., and Svalander C.T. Complement deposition in renal allografts with early malfunction. APMIS 109 (2001) 825