-
1
-
-
42649145667
-
Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, Freeman DJ, Juan T, Sikorski R, Suggs S, Radinsky R, Patterson SD, Chang DD (2008) Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 26: 1626-1634
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
Juan, T.7
Sikorski, R.8
Suggs, S.9
Radinsky, R.10
Patterson, S.D.11
Chang, D.D.12
-
2
-
-
12644273250
-
Biochemical characterization of a novel KRAS insertion mutation from a human leukemia
-
Bollag G, Adler F, elMasry N, McCabe PC, Conner Jr E, Thompson P, McCormick F, Shannon K (1996) Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. J Biol Chem 271: 32491-32494
-
(1996)
J Biol Chem
, vol.271
, pp. 32491-32494
-
-
Bollag, G.1
Adler, F.2
-
3
-
-
34247278727
-
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy
-
Di Fiore F, Blanchard F, Charbonnier F, Le Pessot F, Lamy A, Galais MP, Bastit L, Killian A, Sesboüé R, Tuech JJ, Queuniet AM, Paillot B, Sabourin JC, Michot F, Michel P, Frebourg T (2007) Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy. Br J Cancer 96: 1166-1169
-
(2007)
Br J Cancer
, vol.96
, pp. 1166-1169
-
-
Di Fiore, F.1
Blanchard, F.2
Charbonnier, F.3
Le Pessot, F.4
Lamy, A.5
Galais, M.P.6
Bastit, L.7
Killian, A.8
Sesboüé, R.9
Tuech, J.J.10
Queuniet, A.M.11
Paillot, B.12
Sabourin, J.C.13
Michot, F.14
Michel, P.15
Frebourg, T.16
-
4
-
-
75549087826
-
COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer
-
database issue
-
Forbes SA, Tang G, Bindal N, Bamford S, Dawson E, Cole C, Kok CY, Jia M, Ewing R, Menzies A, Teague JW, Stratton MR, Futreal PA (2009) COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer. Nucleic Acids Res 38(database issue): D652-D657
-
(2009)
Nucleic Acids Res
, vol.38
-
-
Forbes, S.A.1
Tang, G.2
Bindal, N.3
Bamford, S.4
Dawson, E.5
Cole, C.6
Kok, C.Y.7
Jia, M.8
Ewing, R.9
Menzies, A.10
Teague, J.W.11
Stratton, M.R.12
Futreal, P.A.13
-
5
-
-
61449154484
-
KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: Practical application of patient selection
-
Jimeno A, Messersmith WA, Hirsch FR, Franklin WA, Eckhardt SG (2009) KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection. J Clin Oncol 27: 1130-1136
-
(2009)
J Clin Oncol
, vol.27
, pp. 1130-1136
-
-
Jimeno, A.1
Messersmith, W.A.2
Hirsch, F.R.3
Franklin, W.A.4
Eckhardt, S.G.5
-
6
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, Simes RJ, Chalchal H, Shapiro JD, Robitaille S, Price TJ, Shepherd L, Au HJ, Langer C, Moore MJ, Zalcberg JR (2008) K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 359: 1757-1765
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
Simes, R.J.7
Chalchal, H.8
Shapiro, J.D.9
Robitaille, S.10
Price, T.J.11
Shepherd, L.12
Au, H.J.13
Langer, C.14
Moore, M.J.15
Zalcberg, J.R.16
-
7
-
-
0034626694
-
Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling
-
Klockow B, Ahmadian MR, Block C, Wittinghofer A (2000) Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling. Oncogene 19: 5367-5376
-
(2000)
Oncogene
, vol.19
, pp. 5367-5376
-
-
Klockow, B.1
Ahmadian, M.R.2
Block, C.3
Wittinghofer, A.4
-
8
-
-
43249116705
-
Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing
-
Li J, Wang L, Mamon H, Kulke MH, Berbeco R, Makrigiorgos GM (2008) Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nat Med 14: 579-584
-
(2008)
Nat Med
, vol.14
, pp. 579-584
-
-
Li, J.1
Wang, L.2
Mamon, H.3
Kulke, M.H.4
Berbeco, R.5
Makrigiorgos, G.M.6
-
9
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
Lièvre A, Bachet JB, Boige V, Cayre A, Le Corre D, Buc E, Ychou M, Bouché O, Landi B, Louvet C, André T, Bibeau F, Diebold MD, Rougier P, Ducreux M, Tomasic G, Emile JF, Penault-Llorca F, Laurent-Puig P (2008) KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol 26: 374-379
-
(2008)
J Clin Oncol
, vol.26
, pp. 374-379
-
-
Lièvre, A.1
Bachet, J.B.2
Boige, V.3
Cayre, A.4
Le Corre, D.5
Buc, E.6
Ychou, M.7
Bouché, O.8
Landi, B.9
Louvet, C.10
André, T.11
Bibeau, F.12
Diebold, M.D.13
Rougier, P.14
Ducreux, M.15
Tomasic, G.16
Emile, J.F.17
Penault-Llorca, F.18
Laurent-Puig, P.19
-
10
-
-
68749119351
-
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
Loupakis F, Ruzzo A, Cremolini C, Vincenzi B, Salvatore L, Santini D, Masi G, Stasi I, Canestrari E, Rulli E, Floriani I, Bencardino K, Galluccio N, Catalano V, Tonini G, Magnani M, Fontanini G, Basolo F, Falcone A, Graziano F (2009) KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer 101: 715-721
-
(2009)
Br J Cancer
, vol.101
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
Vincenzi, B.4
Salvatore, L.5
Santini, D.6
Masi, G.7
Stasi, I.8
Canestrari, E.9
Rulli, E.10
Floriani, I.11
Bencardino, K.12
Galluccio, N.13
Catalano, V.14
Tonini, G.15
Magnani, M.16
Fontanini, G.17
Basolo, F.18
Falcone, A.19
Graziano, F.20
more..
-
11
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres M, Barbacid M (2003) RAS oncogenes: the first 30 years. Nat Rev Cancer 3: 459-465
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
12
-
-
48649092117
-
High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer
-
Simi L, Pratesi N, Vignoli M, Sestini R, Cianchi F, Valanzano R, Nobili S, Mini E, Pazzagli M, Orlando C (2008) High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer. Am J Clin Pathol 130: 247-253
-
(2008)
Am J Clin Pathol
, vol.130
, pp. 247-253
-
-
Simi, L.1
Pratesi, N.2
Vignoli, M.3
Sestini, R.4
Cianchi, F.5
Valanzano, R.6
Nobili, S.7
Mini, E.8
Pazzagli, M.9
Orlando, C.10
-
13
-
-
0038359432
-
High-resolution genotyping by amplicon melting analysis using LCGreen
-
Wittwer CT, Reed GH, Gundry CN, Vandersteen JG, Pryor RJ (2003) High-resolution genotyping by amplicon melting analysis using LCGreen. Clin Chem 49: 853-860
-
(2003)
Clin Chem
, vol.49
, pp. 853-860
-
-
Wittwer, C.T.1
Reed, G.H.2
Gundry, C.N.3
Vandersteen, J.G.4
Pryor, R.J.5
|